Results 111 to 120 of about 107,653,743 (272)

Intravitreal faricimab in patients with nAMD: French data from the Fight Retinal Blindness! Registry

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess real‐world outcomes of intravitreal faricimab in French patients with neovascular age‐related macular degeneration (nAMD) previously treated with vascular endothelial growth factor (VEGF) inhibitors using data from the Fight Retinal Blindness! (FRB!) Registry.
Eloi Debourdeau, Déborah Harboun, Pierre‐Henry Gabrielle, Yohei Hashimoto, Chloe Chamard, Frederic Michon, Benjamin Wolff, Héloïse Torres‐Villaros, Audrey Giocanti‐Auregan, Mark Gillies, Catherine Creuzot–Garcher, Vincent Daien   +11 more
wiley   +1 more source

Plasmodium falciparum impairs Ang-1 secretion by pericytes in a 3D brain microvessel model

EMBO Molecular Medicine
Disruption of the vascular protective angiopoietin–Tie axis is common in cerebral malaria (CM) patients, who display elevated angiopoietin-2 (Ang-2) and reduced angiopoietin-1 (Ang-1) blood concentrations. The role of pericytes in CM pathogenesis remains
Rory K M Long, François Korbmacher, Paolo Ronchi, Hannah Fleckenstein, Martin Schorb, Waleed Mirza, Mireia Mallorquí, Ruth Aguilar, Gemma Moncunill, Yannick Schwab, Maria Bernabeu   +10 more
doaj   +1 more source

Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2

BMC Cell Biology, 2007
Background The lymphatic system complements the blood circulatory system in absorption and transport of nutrients, and in the maintenance of homeostasis.
Kim Harold, Trinh Jason, Chen Stephen H, Nguyen Vicky PKH, Coomber Brenda L, Dumont Daniel J   +5 more
doaj   +1 more source

Supplementary Figure 4 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody

, 2010
Supplementary Figure 4 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing ...
Hosung Min (2664658), Linh Nguyen (3436241), Sean Caenepeel (2044522), Seog Joon Han (15042480), Anthony Ndifor (1622254), Tom Boone (15042498), Eric Hsu (2025202), Shao Xiong Wang (15042489), Brad Bolon (30121), Mark L. Michaels (2996340), Grant Shimamoto (15042483), Tani Ann Lee (2335246), Richard Kendall (278960), Angela Coxon (431189), Isaac J. Hayward (15042492), Jonathan D. Oliner (1698163), Stephen Kaufman (2446807), Karen Rex (431185), James McCabe (1364808), Paul Hughes (2219167), Haejin Kim (833850), Donald M. McDonald (14882892), Juan Leal (2685292), Ji-Rong Sun (1675660), Dongyin Yu (1698181), Ling Wang (56577), Russell Cattley (15042486), Eunju Hurh (2686873), Beverly L. Falcón (14902658), James Bready (2446822), Luke Li (15042495), Robert Radinsky (278958), Juan Estrada (2446795), David Cordover (15042477)   +33 more
core   +1 more source

Angiogenesis Biomarkers in Ischemic Stroke Patients

Journal of Inflammation Research, 2021
Aziza Alrafiah,1 Ebtisam Alofi,2 Yasser Almohaya,1 Abdullah Hamami,1 Talal Qadah,1 Safa Almaghrabi,2 Nora Hakami,1 Moafaq S Alrawaili,3 Haythum O Tayeb3 1Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz ...
Alrafiah A, Alofi E, Almohaya Y, Hamami A, Qadah T, Almaghrabi S, Hakami N, Alrawaili MS, Tayeb HO   +8 more
doaj  

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Angiopoietin-1 and -2 in Infectious Diseases associated with Endothelial Cell Dysfunction [PDF]

, 2012
Normal endothelial cell function is controlled in part by a tightly regulated balance between angiopoietin-1 and -2 (Ang-1 and Ang-2). Angiopoietin dysregulation (decreased Ang-1 and increased Ang-2) leads to an activated endothelium that is contractile,
Page, Andrea Vaughn
core   +1 more source

Engineering Novel Angiopoietin Receptor Ligands

, 2011
Angiopoietin-1 is a multimeric glycoprotein which signals through the vascular endothelial Tie2 receptor to protect against inflammation and leakage, an effect antagonised by the selectively upregulated antagonist angiopoietin-2. In many pathologies this
Andrew James Moss (7659908)
core   +3 more sources

Angiopoietin-1 for Myocardial Angiogenesis [PDF]

, 2011
In response to ischemic damage, the heart undergoes vicious process of remodeling wherein the damaged myocardium is replaced by scar tissue and as compensatory mechanism, its existing collateral vessels and neovascularization with concomitant changes in cell recruitment, multiplication and cytokine/growth factor action.
Vien Khach, Muhammad Zeeshan, Muhammad Ashraf, Khawaja Husnain   +3 more
openaire   +1 more source