Results 91 to 100 of about 107,653,743 (272)

Association between periodontitis and exudative retinal detachment: A population‐based cohort study

Journal of Periodontology, EarlyView.
Abstract Background To investigate whether periodontitis, a common bacterial‐induced inflammatory condition, serves as a risk factor for exudative retinal detachment (ERD), which results from fluid entering the subretinal space due to damage to the retinal pigment epithelium or leaky intraocular vessels, typically associated with inflammatory ...
Earl Fu, Ming‐Ling Tsai, Tsu‐Hsuan Weng, Chi‐Hsiang Chung, Min‐Wen Fu, Wu‐Chien Chien   +5 more
wiley   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Serum levels of angiopoietin-2 and vascular endothelial growth factor in severe refractory asthma

Egyptian Journal of Chest Disease and Tuberculosis, 2014
Background: Airway and vascular remodeling may play a prominent role in the clinical severity of severe refractory asthma (SRA). Angiopoietin-1 (Ang-1) is an essential mediator of angiogenesis by establishing vascular integrity, whereas angiopoietin-2 ...
Mohamed Hantera, Hamed Abd El-Hafiz, Amira Y. Abdelnaby   +2 more
doaj   +1 more source

Supplementary Figure 1 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody

, 2010
Supplementary Figure 1 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing ...
Hosung Min (2664658), Linh Nguyen (3436241), Sean Caenepeel (2044522), Seog Joon Han (15042480), Anthony Ndifor (1622254), Tom Boone (15042498), Eric Hsu (2025202), Shao Xiong Wang (15042489), Brad Bolon (30121), Mark L. Michaels (2996340), Grant Shimamoto (15042483), Tani Ann Lee (2335246), Richard Kendall (278960), Angela Coxon (431189), Isaac J. Hayward (15042492), Jonathan D. Oliner (1698163), Stephen Kaufman (2446807), Karen Rex (431185), James McCabe (1364808), Paul Hughes (2219167), Haejin Kim (833850), Donald M. McDonald (14882892), Juan Leal (2685292), Ji-Rong Sun (1675660), Dongyin Yu (1698181), Ling Wang (56577), Russell Cattley (15042486), Eunju Hurh (2686873), Beverly L. Falcón (14902658), James Bready (2446822), Luke Li (15042495), Robert Radinsky (278958), Juan Estrada (2446795), David Cordover (15042477)   +33 more
core   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Type XII RTKs: TIE family of angiopoietin receptors in GtoPdb v.2025.3 [PDF]

The TIE family were initially associated with formation of blood vessels (angiogenesis). Endogenous ligands are angiopoietin-1, angiopoietin-2, and angiopoietin-4. angiopoietin-2 appears to act as an endogenous antagonist of angiopoietin-1 function, thus
Peach, Chloe J.
core   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Supplementary Methods, Figure Legends, and References from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody

, 2010
Supplementary Methods, Figure Legends, and References from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing ...
Hosung Min (2664658), Linh Nguyen (3436241), Sean Caenepeel (2044522), Seog Joon Han (15042480), Anthony Ndifor (1622254), Tom Boone (15042498), Eric Hsu (2025202), Shao Xiong Wang (15042489), Brad Bolon (30121), Mark L. Michaels (2996340), Grant Shimamoto (15042483), Tani Ann Lee (2335246), Richard Kendall (278960), Angela Coxon (431189), Isaac J. Hayward (15042492), Jonathan D. Oliner (1698163), Stephen Kaufman (2446807), Karen Rex (431185), James McCabe (1364808), Paul Hughes (2219167), Haejin Kim (833850), Donald M. McDonald (14882892), Juan Leal (2685292), Ji-Rong Sun (1675660), Dongyin Yu (1698181), Ling Wang (56577), Russell Cattley (15042486), Eunju Hurh (2686873), Beverly L. Falcón (14902658), James Bready (2446822), Luke Li (15042495), Robert Radinsky (278958), Juan Estrada (2446795), David Cordover (15042477)   +33 more
core   +1 more source

Primary monocytes regulate endothelial cell survival through secretion of Angiopoietin-1 and activation of endothelial Tie2 [PDF]

, 2010
Objective—Monocyte recruitment and interaction with the endothelium is imperative to vascular recovery. Tie2 plays a key role in endothelial health and vascular remodeling. We studied monocyte-mediated Tie2/angiopoietin signaling following interaction of
Monter-Solans, Juan, Schubert, Shai Y., Benarroch, Alejandro, Elazer R. Edelman, Edelman, Elazer R., Shai Y. Schubert, Alejandro Benarroch, Juan Monter-Solans   +7 more
core   +1 more source

Treg‐stromal cell axis in tissue repair and autoimmune diseases: Mechanisms and clinical translation

Rheumatology &Autoimmunity, EarlyView.
The Treg‐stromal cell axis as a central regulator of tissue repair and immune tolerance. Under physiological conditions, bidirectional communication between Tregs and stromal cells—mediated by cell‐surface molecular contacts, anti‐inflammatory cytokines, and extracellular vesicles—orchestrates inflammation resolution, immune tolerance, and complete ...
Peiyan Zhang, Rongyuan Gao, Zhaohui Zheng   +2 more
wiley   +1 more source