Results 71 to 80 of about 107,653,743 (272)

Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria

American Journal of Hematology, EarlyView.
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho, Hasrini Rini, Noy N. Kambuaya, Syawal Satria, Freis Candrawati, Putu A. I. Shanti, King Alexander, Benediktus Andries, Aisah R. Amelia, Anjana Rai, Kim A. Piera, Agatha M. Puspitasari, Ristya Amalia, Pak Prayoga, Leo Leonardo, Maulina Hafidzah, Theo Situmorang, Dewi S. Margayani, Desandra A. Rahmayenti, Pengxing Cao, Enny Kenangalem, Leily Trianty, Damian Oyong, Julie A. Simpson, Rintis Noviyanti, Pierre A. Buffet, Jeanne R. Poespoprodjo, Nicholas M. Anstey   +27 more
wiley   +1 more source

Angiopoietin-2 and angiopoietin-2/angiopoietin-1 ratio as indicators of potential severity of Plasmodium vivax malaria in patients with thrombocytopenia. [PDF]

PLoS ONE, 2014
Angiogenic factors such as angiopoietin 1 (Ang-1) and angiopoietin 2 (Ang-2) are biomarkers produced during activation and dysfunction of the vascular endothelium in several infectious diseases.
Luciano Teixeira Gomes, Eduardo Rodrigues Alves-Junior, Clebson Rodrigues-Jesus, Andreia Ferreira Nery, Thamires Oliveira Gasquez-Martin, Cor Jesus Fontes   +5 more
doaj   +1 more source

Angiogenin, Angiopoietin-1, Angiopoietin-2, and Endostatin Serum Levels in Inflammatory Bowel Disease

, 2011
Background: Angiogenesis is a complex process, involving a great number of mediators. It is implicated in the pathogenesis of numerous diseases, holding a critical role in inflammatory bowel disease (IBD).
Oikonomou, K. A., Andreas N. Kapsoritakis, Tiaka, E. K., Manolakis, A. C., Fotios D. Tsiopoulos, Spiros P. Potamianos, Kapsoritakis, A. N., Kapsoritaki, A. I., Tsiompanidis, I. A., Konstantinos A. Oikonomou, Tsiopoulos, F. D., Potamianos, S. P., Anastasia I. Kapsoritaki, Anastassios C. Manolakis, Elisavet K. Tiaka, Ilias A. Tsiompanidis   +15 more
core   +1 more source

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Prognostic and Pathogenic Role of Angiopoietin-1 and -2 in Pneumonia

, 2018
RATIONALE: During pneumonia, pathogen-host interaction evokes inflammation and lung barrier dysfunction. Tie2-activation by Angiopoietin-1 reduces, while Tie2-blockade by Angiopoietin-2 increases inflammation and permeability during sepsis.
Norbert Weissmann, Markus Scholz, Mitchell, Tim, Jörg Kaufmann, Weissmann, Norbert, Stefano Aliberti, Neuhauß, Anne-Kathrin, Mitchell, Timothy J, Norbert Suttorp, Aliberti, Stefano, Katrin Reppe, Anne-Kathrin Neuhauß, Ansgar Santel, Timothy J. Mitchell, Santel, Ansgar, Gutbier, Birgitt, Scholz, Markus, Witzenrath, Martin, Suttorp, Norbert, Birgitt Gutbier, Carolin Ehrler, Morawietz, Lars, Stefan Hippenstiel, Martin Witzenrath, Ehrler, Carolin, Hippenstiel, Stefan, Lars Morawietz, Reppe, Katrin, Kaufmann, Jörg   +28 more
core   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Increased frequency of proangiogenic tunica intima endothelial kinase 2 (Tie2) expressing monocytes in individuals with type 2 diabetes mellitus

Cardiovascular Diabetology, 2022
Background Individuals with type 2 diabetes mellitus (T2DM) have an increased risk for developing macrovascular disease (MVD) manifested by atherosclerosis. Phenotypically and functionally different monocyte subsets (classical; CD14++CD16−, non-classical;
M. Reijrink, J. van Ark, C. P. H. Lexis, L. M. Visser, M. E. Lodewijk, I. C. C. van der Horst, C. J. Zeebregts, H. van Goor, S. C. A. de Jager, G. Pasterkamp, B. H. R. Wolffenbuttel, J. L. Hillebrands   +11 more
doaj   +1 more source

Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 1474-1478, April 2025.
Abstract Aims ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.
Petra Büttner, Antje Augstein, Mahmoud Abdellatif, André Lourenço, Adelino Leite‐Moreira, Inês Falcão‐Pires, Sarah Werner, Holger Thiele, Simon Sedej, Antje Schauer, Volker Adams   +10 more
wiley   +1 more source

Rat Tooth Development Following Local Angiopoietin 1 Application: A Histological Examination

Medical Journal of Babylon
Background: Odontogenesis refers to the process by which teeth originate, erupt, and fuse with the tissues around them. Vascularization that occurs due to angiopoietin 1 (ANGPT1) plays an important role in the development of teeth.
Al-Hussein Ali Mohammed Hussein, Enas Fadhil Kadhim   +1 more
doaj   +1 more source

Angiopoietin-2 in chronic renal failure patients on hemodialysis: Relationship with glomerular filtration rate in the predialysis stages

The Egyptian Journal of Internal Medicine, 2013
Introduction Cardiovascular disease has increased as a complication of chronic kidney disease even in the absence of diabetes or hypertension. Angiopoietin-1 and 2 are 55 kDa antagonistic nonredundant gatekeepers of endothelial activation and thus are ...
Fatma A Attia, Nagwa A Mohammed, Al-Shymaa A Ibrahim   +2 more
doaj   +1 more source