Results 51 to 60 of about 107,653,743 (272)

Boxplot and scatter graphs showing the association between the angiopoietin-2/angiopoietin-1 ratio (A), levels of angiopoietin-2 (B), and levels of angiopoietin-1 (C) with platelet counts in P. vivax malaria patients.

, 2014
Boxplot and scatter graphs showing the association between the angiopoietin-2/angiopoietin-1 ratio (A), levels of angiopoietin-2 (B), and levels of angiopoietin-1 (C) with platelet counts in P. vivax malaria patients.
Cor Jesus Fontes (216797), Clebson Rodrigues-Jesus (638369), Eduardo Rodrigues Alves-Junior (638368), Luciano Teixeira Gomes (638367), Andreia Ferreira Nery (638370), Thamires Oliveira Gasquez-Martin (638371)   +5 more
core   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Activation of Tie2 by angiopoietin-1 and angiopoietin-2 results in their release and receptor internalization [PDF]

Journal of Cell Science, 2006
The receptor tyrosine kinase Tie2 is highly expressed in endothelial cells and is crucial for angiogenesis and vascular maintenance. The ligands for Tie2 are the angiopoietins, of which angiopoietin-1 and angiopoietin-2 have been the most studied.
Elena, Bogdanovic, Vicky P K H, Nguyen, Daniel J, Dumont   +2 more
openaire   +2 more sources

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Neutrophil elastase inhibition effectively rescued angiopoietin-1 decrease and inhibits glial scar after spinal cord injury

Acta Neuropathologica Communications, 2018
After spinal cord injury (SCI), neutrophil elastase (NE) released at injury site disrupts vascular endothelium integrity and stabilization. Angiopoietins (ANGPTs) are vascular growth factors that play an important role in vascular stabilization.
Hemant Kumar, Hyemin Choi, Min-Jae Jo, Hari Prasad Joshi, Manjunatha Muttigi, Dario Bonanomi, Sung Bum Kim, Eunmi Ban, Aeri Kim, Soo-Hong Lee, Kyoung-Tae Kim, Seil Sohn, Xiang Zeng, Inbo Han   +13 more
doaj   +1 more source

Stage-dependent angiopoietin-Tie2 and nitric oxide signaling of erythrocytes in response to surgical trauma in head and neck cancer

World Journal of Surgical Oncology, 2020
Background Angiopoietin-Tie2 and nitric oxide pathway is crucial in tumor angiogenesis and closely correlates with tumor development, growth, and metastasis.
Hsiang-Ling Wu, You-Hsiang Chu, Ying-Hsuan Tai, Mei-Yung Tsou, Cheng-Hsien Wu, Wen-Liang Lo, Shyh-Kuan Tai, Chun-Chang Yeh, Chih-Cherng Lu   +8 more
doaj   +1 more source

Hypertension, Vascular Rarefaction and Angiopoietin-1 [PDF]

Korean Circulation Journal, 2011
Refer to the page 590-595 Hypertension is a very common but incompletely understood disease, especially in its pathogenesis and vascular complications occurring in the cardiovascular research filed. There are many explanations for pathological mechanisms in hypertension, including adrenergic over-reactivity, renin-angiotensin-aldosteron system ...
openaire   +2 more sources

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Increased Expression of Angiopoietin 2 and Tie2 in Rosacea

Dermatopathology
In this study we evaluated the expression of Angiopoietin 1, Angiopoietin 2, and Tie2 by immunohistochemistry in the skin of 10 patients with erythemato telangiectatic and papulopustular rosacea.
Aysin Kaya, Jean-Hilaire Saurat, Nathalie Satta, Gürkan Kaya   +3 more
doaj   +1 more source

Angiopoietin-1 and Angiopoietin-2 Expression Imbalance Influence in Early Period After Subarachnoid Hemorrhage [PDF]

International Neurourology Journal, 2016
Purpose Microvascular endothelial integrity is important for maintaining the blood-brain barrier (BBB). However, subarachnoid hemorrhage (SAH) disrupts this integrity, making the BBB dysfunctional—an important pathophysiological change after SAH ...
Hua Gu, Zhen-Hai Fei, Yi-Qi Wang, Jian-Guo Yang, Chao-Hui Zhao, Yong Cai, Xing-Ming Zhong   +6 more
doaj   +1 more source