Results 111 to 120 of about 5,425 (227)

Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone

eFood, Volume 7, Issue 4, August 2026.
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu, Ziyong Mao, Jesus Simal‐Gandara, Zi Chen, Hui Cao   +4 more
wiley   +1 more source

Lycopene Increases Skeletal Muscle Mass by Promoting Myoblast Differentiation

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Lycopene supplementation could increase skeletal muscle mass by promoting myoblast differentiation and muscle protein synthesis. Mechanistic analysis revealed that lycopene could activate ERα, and ERα activation facilitated myogenic differentiation and myotube formation. ABSTRACT Muscle differentiation is a necessary process for the growth, development
Wanxue Wen, Dajiang Ding, Junning Pu, Yong Zhang, Yexia Luo, Jiaxin Du, Daolin Mou   +6 more
wiley   +1 more source

Immunometabolic Dysregulation in Obesity: Integrating Macrophage Polarization, Metabolic Reprogramming, and Gut Microbiota Crosstalk

Immunity, Inflammation and Disease, Volume 14, Issue 8, August 2026.
ABSTRACT Background Obesity is characterized by chronic low‐grade systemic inflammation, in which adipose tissue macrophages (ATMs) play a pivotal role in driving immune and metabolic dysfunction. Objective This review summarizes current evidence on the roles of ATMs in obese adipose tissue and examines how macrophage polarization and metabolic ...
Yuanyuan Li, Jingwei Mao, Yiwen Deng, Xiaobo Ge, Limin Nie, Qun Wang, Ruiqing Wang, Jiarun Zhang, Tianli Lyu, Luopeng Zhao, Lu Liu, Bin Li   +11 more
wiley   +1 more source

Effect of Osteoblast‐Extracellular Matrix‐Functionalized Nanostructured Titanium Surface on Osteoblastic Cell Behavior

Journal of Biomedical Materials Research Part A, Volume 114, Issue 8, August 2026.
ABSTRACT Nanostructured titanium (Ti) facilitates osteoblast differentiation by modulating various signaling pathways and may enhance osseointegration, potentially through its influence on the formation and remodeling of the extracellular matrix (ECM). This study aimed to investigate the impact of osteoblast‐ECM‐functionalized nanostructured Ti surface
Georgia Kors Quiles, Paola Gomes Souza, Maria Paula Oliveira Gomes, Rayana Longo Bighetti‐Trevisan, Leticia Faustino Adolpho, Helena Bacha Lopes, Adalberto Luiz Rosa, Marcio Mateus Beloti   +7 more
wiley   +1 more source

Biomarkers of Endothelial Damage in Acute Graft‐Versus‐Host Disease After Allogenic Hematopoietic Stem Cell Transplantation: Methodological Challenges

Journal of Clinical Laboratory Analysis, Volume 40, Issue 15, August 2026.
Allogeneic hematopoietic stem cell transplantation remains a potentially curative therapy for many hematological malignancies; however, its success is significantly limited by acute graft‐versus‐host disease (aGVHD), a leading cause of post‐transplant morbidity and mortality in which endothelial dysfunction plays a central role.
Katarina Klinar, Helena Podgornik
wiley   +1 more source

Pigment Epithelium-Derived Factor From Müller Cells Is Involved in Angiopoietin-Mediated Survival Control of Retinal Neurons. [PDF]

Invest Ophthalmol Vis Sci
Younis R, Müller H, Ziemssen F, Eichler W.   +3 more
europepmc   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

Divergent Atrial Transcriptomic Signatures in Diabetic and Nondiabetic Atrial Fibrillation

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
Diabetes alters the atrial transcriptome in atrial fibrillation, characterized by enhanced mitochondrial ATP synthesis, suppressed immune and inflammatory pathways, and distinct miRNA expression profiles, suggesting metabolic and epigenetic remodeling of the atrial substrate.
Kenshi Yoshimura, Yuya Kiriake, Hiroki Osanai, Mengyan Wei, Shinichiro Kume, Tatsuki Kurokawa, Masaki Morishima, Ryusuke Suzuki, Shinji Miyamoto, Katsushige Ono   +9 more
wiley   +1 more source

Angiopoietins as biomarkers of schistosomiasis severity: a cross-sectional study - CORRIGENDUM. [PDF]

Parasitology
Coimbra RLS, Meneses GC, Galvão RLF, Pinheiro MCC, de Oliveira LM, Lopes NC, Martins BVB, de Araújo LM, Vieira RYR, Oriá RB, Martins AMC, Daher EF, da Silva ÂM, Bezerra FSM.   +13 more
europepmc   +1 more source

Dynamics in Pro‐Inflammatory Cytokines in Response to Hypoglossal Nerve Stimulation in Obstructive Sleep Apnea

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.
Obstructive sleep apnea (OSA) is associated with chronic low‐grade systemic inflammation. In cases of continuous positive airway pressure (PAP) failure, hypoglossal nerve stimulation (HNS) is a treatment option for OSA but its impact on systemic inflammation to date is unknown.
Ralph Pries, Yi Cai, Kirstin Plötze‐Martin, Sanja Jelic, Jonas Fleckner, Karl‐Ludwig Bruchhage, Armin Steffen   +6 more
wiley   +1 more source