Results 181 to 190 of about 6,404 (202)

Beyond VEGF: Angiopoietin-Tie Signaling Pathway in Diabetic Retinopathy. [PDF]

open access: yesJ Clin Med
Chen-Li G   +7 more
europepmc   +1 more source

Double Antiangiogenic Protein, DAAP, Targeting VEGF-A and Angiopoietins in Tumor Angiogenesis, Metastasis, and Vascular Leakage [PDF]

open access: yesCancer Cell, 2010
SummaryTwo vascular growth factor families, VEGF and the angiopoietins, play critical and coordinate roles in tumor progression and metastasis. A single inhibitor targeting both VEGF and angiopoietins is not available. Here, we developed a chimeric decoy
Koh Gou Young, Byeong Hwa Jeon
exaly   +4 more sources

Angiopoietins in angiogenesis

open access: yesCancer Letters, 2013
Tie-1 and Tie-2 tyrosine kinase receptors are expressed specifically on vascular endothelial cells and on a certain subtype of macrophages implicated in angiogenesis, thus, they have been a major focus of angiogenesis research.
Gerhard Christofori, Ernesta Fagiani
exaly   +2 more sources

Role of angiopoietins in mesothelioma progression

open access: yesCytokine, 2019
Background and objective: Anti-angiogenic treatment has been recently shown to be clinically beneficial for mesothelioma patients. Angiopoietins-1 and -2 are key regulators of tumor angiogenesis.
Sophia Magkouta   +2 more
exaly   +2 more sources

Angiopoietins, abdominal aortic aneurysm and atherosclerosis

open access: yesAtherosclerosis, 2011
Abdominal aortic aneurysm (AAA) and atherosclerosis are common causes of mortality and morbidity in an aging population. Angiogenesis is believed to contribute to the development and progression of these diseases.
Alexandra Trollope, Jonathan Golledge
exaly   +2 more sources

Angiopoietins in inflammation and their implication in the development of inflammatory bowel disease. A review. [PDF]

open access: yesJournal of Crohn's and Colitis, 2014
BackgroundAngiopoietins are essential angiogenic mediators. Since inflammatory bowel disease (IBD) involves inflammation, ulceration and regeneration of the intestinal mucosa, the angiopoietin system has been proposed as a factor to maintain pathological
MarĂ­a Chaparro, Javier P Gisbert
exaly   +2 more sources

VEGF and angiopoietins in diabetic glomerulopathy: How far for a new treatment?

open access: yesMetabolism: Clinical and Experimental, 2012
Diabetic nephropathy (DN) is the major cause of end-stage renal disease in Western countries and its prevalence continues to increase (United States Renal Data System 2010, http://www.usrds.org/). Treatments currently utilised for DN provide only partial
Luigi Gnudi, Alessandra Dei Cas
exaly   +2 more sources

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