Results 71 to 80 of about 34,611,146 (146)

The role of the classical renin–angiotensin system and angiotensin-converting enzyme 2/Ang(1–7)/Mas axis in pulmonary fibrosis

Frontiers in Medicine
Pulmonary fibrosis (PF), a progressive and fatal disease, is characterized by fibroblast proliferation, excessive extracellular matrix deposition, and collagen synthesis. These pathological changes lead to impaired lung structure and function, ultimately
Changhui Lang, Changhui Lang, Bo Huang, Bo Huang, Yan Chen, Yan Chen, Zhixu He, Zhixu He   +7 more
doaj   +1 more source

Plasma and tissue angiotensin‐converting enzyme 2 activity and plasma equilibrium concentrations of angiotensin peptides in dogs with heart disease

Journal of Veterinary Internal Medicine, 2019
Background Angiotensin‐converting enzyme 2 (ACE2) is a homologue of angiotensin‐converting enzyme (ACE) and produces angiotensin peptides (APs), such as angiotensin 1‐9 and 1‐7 that are vasodilatory and natriuretic, and act to counterbalance angiotensin ...
Éva Larouche‐Lebel, Kerry A. Loughran, Mark A. Oyama, Phil F. Solter, Danielle S. Laughlin, Melissa D. Sánchez, Charles‐Antoine Assenmacher, Philip R. Fox, Ryan C. Fries   +8 more
doaj   +1 more source

Impact of angiotensin converting enzyme inhibition on post- coronary artery bypass interleukin 6 release [PDF]

, 2002
Background: Angiotensin 1 converting enzyme (ACE) inhibitors reduce morbidity and mortality after coronary artery bypass graft surgery (CABG). This benefit may result from an anti- inflammatory action.
Humphries, S.E., Rumley, A., Lowe, G.D., Montgomery, H.E., Sanders, J., Brull, D.J.   +5 more
core   +2 more sources

Myocardial and Renal Renin–Angiotensin System Enzyme Activity in Dogs

Journal of Veterinary Internal Medicine
Background Methods to quantify the activity of the tissue renin–angiotensin system (RAS) are needed. Objective To estimate myocardial and renal RAS enzyme activity in postmortem tissues.
Emma C. Weitzhandler, Marisa K. Ames, Machelle D. Wilson, Oliver Domenig   +3 more
doaj   +1 more source

Novel players in cardioprotection: Insulin like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9)

, 2015
Artículo de publicación ISIInsulin-like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9) have been proposed to be important mediators in cardioprotection. A large body of evidence indicates that insulin like growth factor-1 has pleotropic actions
Paz Ocaranza, María, García, Lorena, Ocaranza, María Paz, Chiong Lay, Mario Martín, Bustamante, Mario, Lavandero González, Sergio, Chiong Lay, Mario, Pavez, Mario, García Nannig, Lorena, Westermeier, Francisco   +9 more
core   +1 more source

Angiotensin-(1-7): Pharmacological properties and pharmacotherapeutic perspectives

, 2008
Therapeutic modulation of the renin-angiotensin system is not complete without taking into consideration the beneficial effects of angiotensin-(1-7) in cardiovascular pathology.
Dilek Iusuf, van Gilst, WH, Roks, Anton, Robert H. Henning, Roks, Anton J. M., Anton J.M. Roks, Iusuf, Dilek, Henning, Robert H., Roks, Anton; id_orcid, van Gilst, Wiek H., Wiek H. van Gilst, Iusuf, D, Henning, RH   +12 more
core   +1 more source

Sodium status and angiotensin-converting enzyme inhibition: effects on plasma angiotensin-(1-7) in healthy man

, 2005
Objective Angiotensin-converting enzyme (ACE) inhibitors provide effective intervention for cardiovascular and renal disease. Changes in angiotensin-(1-7) have been proposed to be involved in the mechanism of action of ACE inhibition (ACEi).
Kocks, MJA, Navis, G, Boomsma, F, Lely, AT, de Jong, PE (Paul), de Jong, PE, Lelij, Aart Jan   +6 more
core   +1 more source

Angiotensin-Converting Enzyme 2 Activation Is Not a Common Feature of Angiotensin-Converting Enzyme Inhibitory Peptides

Angiotensin-converting enzyme (ACE) catalyzes the formation of angiotensin II (Ang II), a vasoconstrictor, whereas its homologue ACE2 degrades Ang II into angiotensin (1–7) (Ang (1–7)), a vasodilator.
Zihan Wang (3129810), Jianping Wu (356897), Xiaoyu Bao (1536109), Hongbing Fan (5871203)   +3 more
core   +1 more source

Metabolic Inactivation of Angiotensin 1-7 (Ang 1-7)

, 2019
The renin-angiotensin system (RAS) plays a role in the control of the cardiovascular system by modulating blood pressure. While Angiotensin II (Ang II) serves as a vasoconstrictor and is the most well-known of the RAS peptides, Angiotensin 1-7 (Ang 1-7 ...
Abraham, Christy, Asif, Mahnoor
core   +1 more source

Angiotensin-(1-7) Inhibits Angiogenesis and Alleviates Joint Damage in CIA Mice via the Hippo–YAP Pathway

Shan Zhang, Min Sheng, Dan Yu, Kechen Qian, Yichen Zhang, Wenhan Huang, Feifeng Ren, Lin Tang Department of Rheumatology and Immunology, Second Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Lin ...
Ren F, Tang L, Sheng M, Zhang Y, Huang W, Yu D, Zhang S, Qian K   +7 more
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