Results 11 to 20 of about 280,004 (212)

Physiological and pathological roles of Ang II and Ang- (1-7) in the female reproductive system

open access: yesFrontiers in Endocrinology, 2022
The local Renin-Angiotensin System (RAS) has been demonstrated to exist in a wide range of tissues and organs, In the female reproductive system, it is mainly found in the ovary, uterus and placenta.
Yuanyuan Liu   +8 more
doaj   +1 more source

Effect of angiotensin receptor blockers and angiotensin‐converting enzyme 2 on plasma equilibrium angiotensin peptide concentrations in cats with heart disease

open access: yesJournal of Veterinary Internal Medicine, 2021
Background Little is known about the effect of renin angiotensin aldosterone system‐inhibiting (RAASi) drugs on alternative angiotensin peptides (APs) such as angiotensin 1‐7 (Ang1‐7), which are mediated by angiotensin‐converting enzyme 2 (ACE2 ...
Terry Huh   +3 more
doaj   +1 more source

Anti-Inflammatory Effects of Ang-(1-7) Bone-Targeting Conjugate in an Adjuvant-Induced Arthritis Rat Model

open access: yesPharmaceuticals, 2022
Rheumatoid arthritis (RA) is a chronic inflammatory condition of synovial joints that causes disability and systemic complications. Ang-(1-7), one of the main peptides in the renin-angiotensin (Ang) system (RAS), imposes its protective effects through ...
Sana Khajeh pour   +3 more
doaj   +1 more source

Angiotensin 1‐7 protects against ventilator‐induced diaphragm dysfunction

open access: yesClinical and Translational Science, 2021
Mechanical ventilation (MV) is a life‐saving instrument used to provide ventilatory support for critically ill patients and patients undergoing surgery.
Toshinori Yoshihara   +5 more
doaj   +1 more source

Antihypertensive effects of angiotensin-(1-7)

open access: yesBrazilian Journal of Medical and Biological Research, 1998
Accumulating evidence suggests that angiotensin-(1-7) (Ang-(1-7)) is an important component of the renin-angiotensin system and that the actions of the peptide may either contribute to or oppose those of Ang II.
M.C. Chappell   +3 more
doaj   +1 more source

Effect of angiotensin receptor blockers and angiotensin converting enzyme 2 on plasma equilibrium angiotensin peptide concentrations in dogs with heart disease

open access: yesJournal of Veterinary Internal Medicine, 2021
Background The pathophysiology of heart failure involves maladaptive angiotensin peptides (APs) and enzymes, including angiotensin 2 (AT2) and angiotensin converting enzyme (ACE), as well as recently described alternative components, such as angiotensin ...
Éva Larouche‐Lebel   +3 more
doaj   +1 more source

Angiotensin-(1–7) reduces α-synuclein aggregation by enhancing autophagic activity in Parkinson’s disease

open access: yesNeural Regeneration Research, 2022
Abnormal accumulation of α-synuclein contributes to the formation of Lewy bodies in the substantia nigra, which is considered the typical pathological hallmark of Parkinson’s disease.
Qing Gao   +6 more
doaj   +1 more source

Renin-Angiotensin System: A Review of Historical Perspectives

open access: yesGalician Medical Journal, 2023
The article is a review of publications concerning historical perspectives of the renin-angiotensin system. The discovery of its components is presented in chronological order, beginning with the initial identification of renin and proceeding to the ...
Olga Kovalyova   +2 more
doaj   +1 more source

Angiotensin-(1–7) exerts a protective action in a rat model of ventilator-induced diaphragmatic dysfunction

open access: yesIntensive Care Medicine Experimental, 2019
Background Ventilator-induced diaphragmatic dysfunction (VIDD) is a common event during mechanical ventilation (MV) leading to rapid muscular atrophy and contractile dysfunction. Recent data show that renin-angiotensin system is involved in diaphragmatic
Vanessa Zambelli   +7 more
doaj   +1 more source

The Role of Renin–Angiotensin System in Diabetic Cardiomyopathy: A Narrative Review

open access: yesLife, 2023
Diabetic cardiomyopathy refers to myocardial dysfunction in type 2 diabetes, but without the traditional cardiovascular risk factors or overt clinical atherosclerosis and valvular disease.
João Pedro Thimotheo Batista   +3 more
doaj   +1 more source

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