Results 51 to 60 of about 146,093 (222)
Biomedicines, 2022 Diminazene aceturate (DIZE) is a putative angiotensin-converting enzyme 2 (ACE2) activator and angiotensin type 1 receptor antagonist (AT1R). Its simple chemical structure possesses a negatively charged triazene segment that is homologous to the ...
John M. Matsoukas +12 more
doaj +1 more source
Chinese Medical Journal, 2008 BACKGROUND Angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II type 1 receptor blockers (ARB) can inhibit tumor growth by inhibition of angiogenesis.
Liang Wang +6 more
semanticscholar +1 more source
ESC Heart Failure, 2023 Aims This study aims to provide representative information on heart failure (HF) patients in China, especially older adults aged ≥75 years. We aim to clarify the age‐related discrepancies in performance measures and the modifying effect of age on the ...
Cong Yuan +10 more
doaj +1 more source
Angiotensin Type 1 Receptor Blockers in Heart Failure.
Current Drug Targets, 2020 Homeostasis in the cardiovascular system is maintained by physiological functions of the Renin Angiotensin Aldosterone System (RAAS). In pathophysiological conditions, over activation of RAAS leads to an increase in the concentration of Angiotensin II ...
K. D. Singh, S. Karnik
semanticscholar +1 more source
Clinical and Experimental Hypertension, 2019 Backgrounds and aims: Increased arterial stiffness may increase cardiovascular morbidity and mortality. Angiotensin II type 1 receptor blockers (ARBs) are potentially useful in controlling the central blood pressure and arterial stiffness in mild to ...
Mo-Li Zhu +10 more
doaj +1 more source
Angiotensin II type 1 receptor blocker inhibits arterial calcification in a pre-clinical model [PDF]
Cardiovascular Research, 2010 Arterial calcification is a common complication of several disorders and is a strong predictor of mortality. The mechanism underlying arterial calcification is not fully understood and as such, no pharmaceutical therapies are currently available which impede its progression.
Zachary B, Armstrong +3 more
openaire +2 more sources
Angiotensin II inhibitor facilitates epidermal wound regeneration in diabetic mice
Frontiers in Physiology, 2015 Tissue regeneration and wound healing are severely impaired in diabetes and are associated with poor circulation and dysfunctional blood vessels. Angiotensin II inhibitors are anti-hypertensive drugs used in clinical practice to regulate blood pressure ...
Maria eKamber +6 more
doaj +1 more source
Frontiers in Endocrinology, 2022 ObjectivesIgA nephropathy (IgAN) is the most common primary glomerular disease, and is the leading cause of chronic renal failure. Because mesangial lesions are the main pathological changes seen in IgAN, we investigated factors associated with the ...
Yetong Li +5 more
doaj +1 more source
Efficacy of Combined Bevacizumab and Angiotensin-Converting Enzyme Inhibitors or Angiotensin II type 1 Receptor Blockers in Metastatic Colorectal Cancer Patients [PDF]
Middle East Journal of CancerBackground: Bevacizumab, used in the treatment of metastatic colorectal cancer (mCRC), has an angiogenesis inhibitory effect. Angiotensin converting enzyme inhibitors (ACEi) and angiotensin II type 1 receptor blockers (ARBs) used in the treatment of ...
Ali Kaan Güren +13 more
doaj +1 more source
Beneficial effects of the activation of the angiotensin-(1-7) MAS receptor in a murine model of adriamycin-induced nephropathy. [PDF]
PLoS ONE, 2013 Angiotensin-(1-7) [Ang-(1-7)] is a biologically active heptapeptide that may counterbalance the physiological actions of angiotensin II (Ang II) within the renin-angiotensin system (RAS). Here, we evaluated whether activation of the Mas receptor with the
Kátia Daniela Silveira +9 more
doaj +1 more source