Results 61 to 70 of about 8,783 (159)
Expression of angiotensin II type 1 receptor in rat bladder smooth muscle cells in response to a streptzotocin induced diabetes mellitus model [PDF]
, 2012 Introduction: The aim of this study was to investigate angiotensin II type 1 (AT1) receptors in rat bladder smooth muscle cells and alterations of AT1 receptors by diabetes mellitus and diuretic states.
Tobu, Shohei +5 more
core +1 more source
Scientific Reports, 2022 Kidney fibrosis is a common pathway that leads to chronic kidney disease. Angiotensin II type-1 receptor (AT1R)-associated protein (ATRAP) was originally identified as an AT1R-binding protein.
Eriko Abe +13 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Angiotensin II type 1 receptor blockers (ARBs) have been shown to limit the growth of abdominal aortic aneurysm (AAA), but their efficacy is controversial.
Kohei Karasaki +6 more
doaj +1 more source
, 2010 Adverse events in pregnancy may 'programme' offspring for the later development of cardiovascular disease and hypertension. Previously, using a rodent model of programmed hypertension we have demonstrated the role of the renin-angiotensin system in this ...
Irina Bogdarina +13 more
core +1 more source
Journal of Pharmacological Sciences, 2010 Based on radioligand binding and signal transduction assays in our previous study, we have determined the binding pattern and functional efficacy of the constitutively active mutant N111G of angiotensin II type 1 (AT1) receptor.
Mohiuddin Ahmed Bhuiyan +4 more
doaj +1 more source
Genetic Polymorphisms of the Angiotensin Ii Type 1 Receptor Gene and Diastolic Heart Failure
, 2011 Objectives The aim of the study was to investigate the association between angiotensin II type 1 receptor (AGTR1) gene polymorphisms and diastolic heart failure (DHF) in a case controlled study.
WU, CHO-KAI;TSAI, CHIA-TI;CHANG, YI-CHENG;LUO, JING-LING;WANG, YI-CHIH;HWANG, JUEY-JEN;LIN, JIUNN-LEE;TSENG, CHUEN-DEN;CHIANG, FU-TIEN +1 more
core +1 more source
Ontogeny of angiotensin type 2 and type 1 receptor expression in mice [PDF]
Journal of the Renin-Angiotensin-Aldosterone System, 2012 In the current experiment, we determined angiotensin type 2 receptor (AT2R) and angiotensin type 1 receptor (AT1R) protein expression by western blot analysis in developing normal mice. The results indicate that: (1) in all detected brain regions and in the spinal cord, adult mice exhibited significantly higher AT2R expression and lower AT1R expression
Juan, Gao +6 more
openaire +2 more sources
Effects of Circulating and Local Uteroplacental Angiotensin II in Rat Pregnancy.
, 2010 The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the renin-Ang system is important in preeclampsia (PE). Female rats transgenic for the human angiotensinogen gene crossed with males transgenic for the human ...
Muller, DN +38 more
core +1 more source
Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease. [PDF]
, 2005 BACKGROUND: Morbidity in COPD results from a combination of factors including hypoxia-induced pulmonary hypertension, in part due to pulmonary vascular remodelling. Animal studies suggest a role of angiotensin II and acute studies in man concur.
Shakur, B Haleema +17 more
core +1 more source
Angiotensin II type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin II type 1 receptor antagonist [PDF]
FEBS Letters, 2001 We investigated the expression of angiotensin II type 1 receptor (AT1) in pancreatic cancer. Both AT1 mRNA and protein were expressed in human pancreatic cancer tissues and cell lines. Binding assays showed that pancreatic cancer cells have specific binding sites for angiotensin II and that binding could be eliminated by treatment with a selective AT1 ...
Fujimoto, Yoshifumi +3 more
openaire +2 more sources