Journal of the Formosan Medical Association, 2009 Acute urinary bladder distension (AUBD) can activate bladder mechanical afferent and renal sympathetic nerves, which contributes to renal vasoconstriction.
Show-Shing Chen +4 more
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Molecular-genetic assessment of angiotensin-converting enzyme hyperactivity determinancy risk at hemorrhagic fever with renal syndrome [PDF]
Саратовский научно-медицинский журнал, 2010 The research aimed to explore the changes of angiotensin-converting enzyme (ACE) blood activity and polymorphism of the angiotensin II type 1 receptor gene as disease predictor at hemorrhagic fever with renal syndrome (HFRS). In exami¬nation 409 patients
A.A. Baygildina +4 more
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Post-Transcriptional Control of Angiotensin II Type 1 Receptor Regulates Osteosarcoma Cell Death
Cellular Physiology and Biochemistry, 2018 Background/Aims: MicroRNAs (miRNAs) play an essential role in the tumorigenesis of osteosarcoma (OS). However, the effects of miR-1248 on chemo-resistant potential of OS have not been studied. Here, we addressed this question.
Yue Zhao, Kaicheng Xu, Peng Liu
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The angiogenic response to Bradykinin "in vitro" : the role of Bradykinin receptors in hypoxic hearts and tumors [PDF]
, 2004 End organ damage resulting from hypertension is a leading cause of morbidity and mortality worldwide. In hypertension, left ventricular mass increases resulting in left ventricular hypertrophy (LVH). LVH increases the risk of heart failure and sudden
Neysari, Shiva
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Pharmacogenomics and Personalized Medicine, 2022 Linfa Chen,1,2,* Ying Wang,1,3,* Yajun Wang,4,* Shaoting Huang,1,3 Zhaochun Wu,1,3 Jiawen He,1,3 Wangtao Zhong,3 Bin Zhao,1,3 Guoda Ma,1,4 You Li1,5 1Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases, Affiliated Hospital ...
Chen L +9 more
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Stem Cell Research, 2017 Obesity is often associated with high systemic and local activity of renin-angiotensin system (RAS). Mesenchymal stem cells of adipose tissue are the main source of adipocytes.
Veronika Y. Sysoeva +6 more
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Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease. [PDF]
, 2005 BACKGROUND: Morbidity in COPD results from a combination of factors including hypoxia-induced pulmonary hypertension, in part due to pulmonary vascular remodelling. Animal studies suggest a role of angiotensin II and acute studies in man concur.
Shakur, B Haleema +17 more
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Angiotensin II type 1 receptor blockers increase tolerance of cells to copper and cisplatin
, 2014 The human pathology Wilson disease (WD) is characterized by toxic copper (Cu) accumulation in brain and liver, resulting in, among other indications, mitochondrial dysfunction and apoptosis of hepatocytes.
David Cassiman +8 more
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Inhibition of sequestration of human B-2 bradykinin receptor by phenylarsine oxide or sucrose allows determination of a receptor affinity shift and ligand dissociation in intact cells [PDF]
, 2004 Depending on their interaction with intracellular proteins, G proteincoupled receptors (GPCR) often display different affinities for agonists at 37degreesC. Determining the affinity at that temperature is often difficult in intact cells as most GPCRs are
Faussner, Alexander +3 more
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Angiotensin converting enzyme and vascular endothelial growth factor responses to exercise training in claudicants: the role of ace inhibition [PDF]
, 2009 Exercise training is well recognised as an effective treatment for intermittent claudication. The mechanism underlying exercise induced improvements is multi-factorial but remains poorly understood.
Ng, P.
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