Results 101 to 110 of about 9,454 (174)

ANGPTL4 protected MSCs from hypoxia/SD-induced apoptosis.

, 2014
Apoptosis was measured by flow cytometry and TUNEL assay in MSCs pre-incubated with ANGPTL4 (100 ng/mL) for 1 hr, and then either kept (ANGPTL4 Pre-1 hr +24 hr) or removed (ANGPTL4 Pre-1 hr) during a 24 hr hypoxia/SD condition.
Jinjin Cui (511760), Rui Jiang (264894), Jingjin Liu (393236), Yongshun Wang (393237), Bo Yu (241082), Kai Liu (159026), Wenhua Liu (393239), Meng Hou (393241), Li Yin (286335), Fang Liu (13271)   +9 more
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ANGPTL4: A Comprehensive Review of 25 Years of Research

Angiopoietin-like 4 (ANGPTL4) is a secreted glycoprotein that was discovered in 2000 by three independent laboratories. In the ensuing two and a half decades, extensive work has been conducted to determine its physiological and pathological functions ...
Kleberg, Jeremy, Kolb, Ryan, Ryan Kolb, Jeremy Kleberg, Chandra K. Maharjan, Maharjan, Chandra K., Qiongyu Shi, Weizhou Zhang, Shi, Qiongyu, Zhang, Weizhou, Pedro Ramos, Ramos, Pedro   +11 more
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ANGPTL4 is produced by entero-endocrine cells in the human intestinal tract

, 2014
Gut hormones produced by entero-endocrine cells (EEC) located throughout the gastrointestinal tract play a major role in the regulation of glucose and energy homeostasis.
Tan, N.S., Kersten, A.H., Lichtenstein, Laeticia, Tan, Nguan Soon, Dijk, W., Mensink, Ronald, Dijk, Wieneke, Lichtenstein, L.L., Kersten, S., Mensink, R.P., Alex, S., Lichtenstein, L., Alex, Sheril, Kersten, Sander   +13 more
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Expression of angiopoietin-like 4 in human gastric cancer: ANGPTL4 promotes venous invasion [PDF]

, 2010
There is strong evidence that the angiopoietin family is involved in the regulation of tumour progression, cellular growth and differentiation. Recently, it has been reported that angiopoietin-like 4 (ANGPTL4) in cancer cell promotes the metastatic ...
Taguchi, Takashi, Hirakawa, Hiroshi, Nagayasu, Takeshi, Abe, Kuniko, Nakayama, Toshiyuki, Shibata, Kenichiro   +5 more
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Plasma angiopoietin-like protein 4 as a novel biomarker predicting 10-year mortality in a community-based population: a longitudinal cohort study

Archives of Medical Science
Introduction Angiopoietin-like protein 4 (ANGPTL4) is a hepatokine implicated in fat metabolism regulation. Its genetic inactivation has been associated with improved glucose homeostasis, while elevated plasma ANGPTL4 levels are observed in diabetic and ...
Kang-Chih Fan, Szu-Chi Chen, I-Weng Yen, Chia-Hung Lin, Chun-Heng Kuo, Ya-Pin Lyu, Hsien-Chia Juan, Mao-Shin Lin, Shu-Huei Wang, Hung-Yuan Li   +9 more
doaj   +1 more source

Short chain fatty acids induce ANGPTL4 via PPARγ

, 2013
Angiopoietin-like protein 4 (ANGPTL4, also referred to as Fiaf) has been proposed as circulating mediator between the gut microbiota and fat storage in adipose tissue. Very little is known about mechanisms of regulation of ANGPTL4 in the colon.
Muller, Michael, Lange, Katja, Hooiveld, Guido   +2 more
core  

Angptl4 in podocytes gradually migrated to the GBM in passive Heymann nephritis (PHN) rats (magnification, x400).

, 2014
(A) Immunofluorescence of glomerular Angptl4 with RECA-1, an endothelial marker, in PHN rats on day 7. (B) Immunofluorescence of glomerular Angptl4 with OX-7, a mesangial cell marker, in PHN rats on day 7.
Jing Ma (24574), Shi-Yao Wei (622760), Rui Cui (622759), Xiao Chen (260187), Bing Li (43671), Qiu-Ju Wei (622761), Lei Peng (260321)   +6 more
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The ANGPTL4-HIF-1α loop: a critical regulator of renal interstitial fibrosis

Journal of Translational Medicine
Background Renal interstitial fibrosis (RIF) is a progressive, irreversible terminal kidney disease with a poor prognosis and high mortality. Angiopoietin-like 4 (ANGPTL4) is known to be associated with fibrosis in various organs, but its impact on the ...
Yan Li, Shuang Chen, Qian Yang, Xiao Liu, Weiming Zhou, Ting Kang, Weihua Wu, Santao Ou   +7 more
doaj   +1 more source

ANGPTL4-mediated microglial lipid droplet accumulation: Bridging Alzheimer's disease and obesity

Neurobiology of Disease
Increasing evidence suggests that metabolic disorders such as obesity are implicated in the development of Alzheimer's disease (AD). The pathological buildup of lipids in microglia is regarded as a key indicator in brain aging and the progression of AD ...
Nan Li, Xiaojun Wang, Ruilang Lin, Fuxia Yang, Hung-Chen Chang, Xuchao Gu, Jun Shu, Guidong Liu, Yongfu Yu, Wenshi Wei, Zhijun Bao   +10 more
doaj   +1 more source

Associations of Circulating ANGPTL3, C-Terminal Domain-Containing ANGPTL4, and ANGPTL3/8 and ANGPTL4/8 Complexes with LPL Activity, Diabetes, Inflammation, and Cardiovascular Mortality.

BACKGROUND: ANGPTL3/4/8 (angiopoietin-like proteins 3, 4, and 8) are important regulators of LPL (lipoprotein lipase). ANGPTL8 forms complexes with ANGPTL3 and ANGPTL4.
Silbernagel, Günther;Chen, Yan Q;Li, Hongxia;Lemen, Deven;Wen, Yi;Zhen, Eugene Y;Rief, Martin;Kleber, Marcus E;Delgado, Graciela E;Sarzynski, Mark A;Qian, Yue-Wei;Schmidt, Boerge;Erbel, Raimund;Trampisch, Ulrike S;Moissl, Angela P;Rudolf, Henrik;Schunkert, Heribert;Stang, Andreas;März, Winfried;Trampisch, Hans J;Scharnagl, Hubert;Konrad, Robert J
core   +1 more source