Results 91 to 100 of about 8,972 (208)
GR and Foxa1 promote the transcription of ANGPTL4 in bovine adipocytes
Molecular and Cellular Probes, 2019 ANGPTL4 (angiopoietin-like 4) is a secreted protein involved in triacylglycerol homeostasis. It is a key enzyme in lipolysis, which stimulates the oxidation of fatty acids and inhibits fat accumulation by inhibiting the activity of lipoprotein lipase (LPL).Xue, Mi, Yue, Ning, Xiaoyu, Wang, Zainaguli, Junjvlieke, Li, Wang, Shijie, Wang, Weiyi, Zhang, Xiaotong, Su, Linsen, Zan +8 moreopenaire +2 more sourcesANGPTL4 accelerates ovarian serous cystadenocarcinoma carcinogenesis and angiogenesis in the tumor microenvironment by activating the JAK2/STAT3 pathway and interacting with ESM1
Journal of Translational MedicineBackground Ovarian cancer (OC) is a malignant neoplasm that displays increased vascularization. Angiopoietin-like 4 (ANGPTL4) is a secreted glycoprotein that functions as a regulator of cell metabolism and angiogenesis and plays a critical role in ...Yu-kun Li, An-bo Gao, Tian Zeng, Dan Liu, Qun-feng Zhang, Xiao-min Ran, Zhen-zi Tang, Yan Li, Jue Liu, Ting Zhang, Gang-qing Shi, Wen-chao Zhou, Wen-da Zou, Juan Peng, Juan Zhang, Hui Li, Juan Zou +16 moredoaj +1 more source0391 : Molecular mechanisms of ANGPTL4-induced regulation of vascular integrity
, 2015 Cardiovascular ischemic injuries are associated with vascular damage induced by loss of endothelial junction integrity. Deciphering the mechanisms involved in the regulation of vascular integrity is of major interest in order to develop relevant ...Liabotis, Athanasia, Gomez-Perdiguero, Elisa, Muller, Laurent, Faye, Clément, Germain, Stéphane, Monnot, Catherine, Ricard-Blum, Sylvie, Galaup, Ariane +7 morecore +1 more sourceHypothalamic Angptl4/Fiaf Is a Novel Regulator of Food Intake and Body Weight
, 2010
OBJECTIVE
The angiopoietin-like protein 4 (Angptl4)/fasting-induced adipose factor (Fiaf) is known as a regulator of peripheral lipid and glucose metabolism.Jae Bum Kim, Byung-Soo Youn, Ja Hyun Baik, Young-Bum Kim, Mi-Seon Shin, Kyeong Han Park, Joong-Yeol Park, Ki-up Lee, Churl Namkoong, Min-Seon Kim, Hyun-Kyong Kim +10 morecore +1 more sourceGenetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes [PDF]
, 2018 Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient partitioning.Benotti, Peter N,, Shah, Svati H., Marylyn D. Ritchie, Benotti, Peter N., Dwivedi, Om Prakash, Lee, Wen-Jane, Ritchie, Marylyn D, Wulff, AB, Gromada, Jesper,, Aris Baras, McCarthy, Mark I, Jonas B. Nielsen, Teslovich, Tanya M., Leader, Joseph B., H. Lester Kirchner, Dewey, Frederick E, Yancopoulos, GD, Cristopher V. Van Hout, Hveem, Kristian, Wardeh, AH, Teslovich, Tanya M,, Tybjærg-Hansen, Anne, Murray, MF, Groop, L, Boehnke, M, Oddgeir L. Holmen, Emdin, Connor A., Stefansson, Kari,, Tybjærg-Hansen, A, Murphy, AJ, Damrauer, Scott, Emdin, Connor A,, Penn, J, O'Dushlaine, C, Marcketta, Anthony, Gromada, Jesper, Kirchner, H. Lester, Frederick E. Dewey, Gusarova, Viktoria,, Florez, Jose C.,, Ola Hansson, Gudbjartsson, Daníel Fannar, Reid, Jeffrey G, Borecki, IB, Kathiresan, Sekar,, Melander, Olle,, Borecki, Ingrid B., Damrauer, S, Flannick, Jason, Brummett, Chad M., Khera, Amit V,, Shuldiner, Alan R., Khera, Amit V., Anthony Marcketta, Emdin, Connor A, Steinthorsdottir, Valgerdur,, Shah, Svati H, Bruse, S, Stefansson, K, Habegger, L, Natarajan, Pradeep,, Nielsen, Jonas B., Kwee, Lydia C., George D. Yancopoulos, Boehnke, Michael,, Gudbjartsson, Daniel F, Nielsen, Jonas B,, Prasad, RB, Pradeep Natarajan, Mirshahi, Tooraj,, Kwee, Lydia C,, Aeron Small, Yancopoulos, George D., Viktoria Gusarova, Ledbetter, DH, Kari Stefansson, Fritsche, L, Nordestgaard, Børge G,, Lee-Ming Chuang, Nordestgaard, Børge G., Leader, Joseph B, Valgerdur Steinthorsdottir, Lotta, Luca A, Florez, Jose C, Kirchner, HL, Mirshahi, UL, Chen, Yii Der I., Chuang, L-M, Birtwell, David,, Lydia C. Kwee, Unnur Thorsteinsdottir, David H. Ledbetter, Wardeh, Amr H., Fetterolf, SN, Kraus, WE, Wareham, Nicholas J, Mirshahi, Uyenlinh L., Still, Christopher D, Sulem, P, Groop, Leif,, Jerome I. Rotter, Benotti, Peter N, Holmen, Oddgeir L, Hveem, K, Baras, A, Marju Orho-Melander, David Birtwell, Cristen J. Willer, Flannick, Jason,, Willer, CJ, Anders Berg Wulff, Shannon Bruse, Christopher D. Still, Still, CD, Rader, Daniel J., Kathiresan, S, Fetterolf, Samantha N., Jesper Gromada, Habegger, Lukas, Altshuler, D, Sjögren, M, Small, A, Holmen, OL, Scott Damrauer, Steinthorsdottir, V, Holm, Hilma,, Anne Tybjærg-Hansen, Sulem, Patrick,, Boehnke, Michael, Florez, Jose, McCarthy, MI, Prasad, Rashmi B, Borecki, Ingrid B, Small, Aeron, Gottesman, Omri,, Mirshahi, Uyenlinh L, Thorsteinsdottir, Unnur, Jeffrey G. Reid, Wen-Jane Lee, Small, Aeron,, Willer, Cristen J,, Fritsche, Lars, Holmen, Oddgeir L., Abecasis, Goncalo R., Willer, Cristen J., Wulff, Anders Berg,, Steinthorsdottir, Valgerdur, Mark I. McCarthy, Dewey, Frederick E,, Dewey, Frederick E., Fetterolf, Samantha N, Gusarova, Viktoria, John D. Overton, Mahajan, A, Lotta, LA, Reid, JG, Hansson, Ola,, Wareham, Nicolas J, Lopez, AE, Sulem, Patrick, Birtwell, David, Morris, AP, Teslovich, Tanya M, Om Prakash Dwivedi, Kwee, LC, McCarthy, Mark I., Gudbjartsson, DF, Robert A. Scott, Olle Melander, Shah, SH, Rashmi B. Prasad, Hilma Holm, Still, Christopher D., Nielsen, Jonas B, Morris, Andrew P, Scott, Robert A., Lukas Habegger, O'Dushlaine, Colm, Rotter, Jerome I, Van Hout, Cristopher V, Tybjaerg-Hansen, Anne,, Chen, YDI, Uyenlinh L. Mirshahi, Kraus, William E, Ritchie, MD, Khera, Amit V, Nicholas J. Wareham, O’Dushlaine, Colm, William E. Kraus, Kristian Hveem, Børge G. Nordestgaard, Murphy, Andrew J, Murphy, Andrew J., Holm, H, Teslovich, TM, Carey, David J, Stefansson, Kari, Teresa Tusie-Luna, Sekar Kathiresan, Prasad, Rashmi B., Nordestgaard, BG, Florez, JC, Jose C. Florez, Rader, Daniel J, Khera, Amit, McCarthy, Mark, Reid, Jeffrey G., Abecasis, Goncalo R, Sjögren, Marketa, Lopez, Alexander E., Chuang, Lee-Ming,, Shah, Svati, Tooraj Mirshahi, Lund University., Marcketta, A, Morris, Andrew P; id_orcid, Omri Gottesman, Daniel F. Gudbjartsson, Mahajan, Anubha,, Mirshahi, Tooraj, Mirshahi, T, Orho-Melander, Marju, Hansson, Ola, Goncalo R. Abecasis, Jason Flannick, Chen, Yii-Der Ida, Scott, Robert A, Overton, John D, O'Dushlaine, Colm,, Lotta, Luca A., Lotta, Luca A.,, Lars Fritsche, Murray, Michael F., Willer, Cristen J, Murray, Michael F,, Lee, Wen-Jane,, Holm, Hilma, Tusie-Luna, T, Marketa Sjögren, Holmen, Oddgeir L.,, Scott, RA, Lee, WJ, Tanya M. Teslovich, Baras, Aris,, Lee, W-J, Chuang, Lee-Ming, Murray, Michael F, Connor A. Emdin, Nordestgaard, Børge G, Wareham, NJ, Wulff, Anders Berg, Hartle, Cassandra M, Brummett, Chad M, Holmen, Oddgeir Lingaas, Chen, Yii-Der I., Dewey, FE, Shuldiner, Alan R, Tybjaerg-Hansen, Anne, Melander, O, Emdin, CA, Van Hout, Cristopher V., Thorsteinsdottir, U, Alan R. Shuldiner, Morris, Andrew P., Brummett, CM, Van Hout, Cristopher V,, Hveem, Kristian,, Overton, John D., Chen, Y-DI, Chad M. Brummett, Hartle, Cassandra M., Lopez, Alexander E, Colm O’Dushlaine, Leader, JB, Morris, Andrew P,, Michael F. Murray, Melander, Olle, Chuang, LM, Overton, JD, Ingrid B. Borecki, Birtwell, D, David Altshuler, Orho-Melander, Marju,, Ida Chen, Yii-Der, Cassandra M. Hartle, Tusie-Luna, Teresa, Daniel J. Rader, Michael Boehnke, Wareham, Nicholas J., Baras, Aris, Ledbetter, David H, Fritsche, Lars,, Ritchie, Marylyn D., Hartle, CM, Khera, AV, Shuldiner, AR, Chuang, Lee Ming, Sjögren, Marketa,, Andrew J. Murphy, Nielsen, JB, Kathiresan, Sekar, Abecasis, GR, Luca A. Lotta, Florez, Jose C., Yancopoulos, George D, Carey, DJ, Alexander E. Lopez, Ledbetter, David H., Rader, DJ, Natarajan, P, Samantha N. Fetterolf, Amit V. Khera, Carey, David J., Svati H. Shah, Shah, Svati,, Dwivedi, OP, Altshuler, David,, Natarajan, Pradeep, Abecasis, Goncalo, Anubha Mahajan, Patrick Sulem, Van Hout, CV, Flannick, J, Joseph B. Leader, Amr H. Wardeh, David J. Carey, Gromada, J, Lee, Wen Jane, Prasad, Rashmi B,, Kirchner, H Lester, Orho-Melander, M, Kraus, William E,, Gudbjartsson, Daniel F., Kraus, William E., Leif Groop, Hansson, O, Penn, John, Groop, Leif, Kwee, Lydia C, Peter N. Benotti, Rotter, Jerome I., Benotti, PN, Andrew P. Morris, Gottesman, O, Chen, Yii-Der I, Gusarova, V, Gottesman, Omri, Wardeh, Amr H, Mahajan, Anubha, John Penn, Rotter, JI, Bruse, Shannon, Yii-Der I. Chen, Altshuler, David +353 morecore +1 more sourceANGPTL4 silencing via antisense oligonucleotides reduces plasma triglycerides and glucose in mice without causing lymphadenopathy
, 2022 Angiopoietin-like 4 (ANGPTL4) is an important regulator of plasma triglyceride (TG) levels and an attractive pharmacological target for lowering plasma lipids and reducing cardiovascular risk.Anne Sadewasser, Kersten, Sander,, Jaschinski, Frank,, Nilsson, Stefan K.,, Michel, Sven,, Mingjuan Deng, Michel, Sven, Jaschinski, Frank, Sadewasser, Anne,, Olivecrona, Gunilla,, Kutrolli, Elda, Stefan K. Nilsson, Joibari, Masoumeh Motamedi,, Kersten, Sander, Sven Michel, Elda Kutrolli, Deng, Mingjuan, Gunilla Olivecrona, Deng, Mingjuan,, Frank Jaschinski, Sander Kersten, Joibari, Masoumeh Motamedi, Sadewasser, Anne, Nilsson, Stefan K., Olivecrona, Gunilla, Kutrolli, Elda,, Masoumeh Motamedi Joibari +26 morecore +1 more sourceANGPTL4 Induction by Prostaglandin E2 under Hypoxic Conditions Promotes Colorectal Cancer Progression
, 2011 Prostaglandin E2 (PGE2), the most abundant COX-2–derived prostaglandin found in colorectal cancer, promotes tumor cell proliferation and survival via multiple signaling pathways. However, the role of PGE2 in tumor hypoxia is not well understood. Here, we Yun-Yong Park, Dingzhi Wang, Sang-Wook Kim, Raymond N. DuBois, Ju-Seog Lee, Sun-Hee Kim +5 morecore +1 more sourceANGPTL4 T266M variant is associated with reduced cancer invasiveness
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2017 Angiopoietin-like 4 (ANGPTL4) is a secretory protein that can be cleaved to form an N-terminal and a C-terminal protein. Studies performed thus far have linked ANGPTL4 to several cancer-related and metabolic processes. Notably, several point mutations in the C-terminal ANGPTL4 (cANGPTL4) have been reported, although no studies have been performed that ...Zhen Wei Tan, Ziqiang Teo, Carol Tan, Chee Chong Choo, Wei Sheng Loo, Yiyang Song, Zhi Yang Tam, Sean Pin Ng, Hong Zheng Koh, Yi Siang Ng, Susana Geifman Shochat, Yin Hoe Yau, Pengcheng Zhu, Nguan Soon Tan +13 moreopenaire +4 more sources
