Results 71 to 80 of about 9,454 (174)

Helicobacter pylori-Induced Angiopoietin-Like 4 Promotes Gastric Bacterial Colonization and Gastritis

Research
Helicobacter pylori infection is characterized as progressive processes of bacterial persistence and chronic gastritis with features of infiltration of mononuclear cells more than granulocytes in gastric mucosa.
Rui Xie, Nan You, Wan-Yan Chen, Peng Zhu, Pan Wang, Yi-Pin Lv, Geng-Yu Yue, Xiao-Lin Xu, Jiang-Bo Wu, Jing-Yu Xu, Si-Xu Liu, Mu-Han Lü, Sheng-Qian Yang, Ping Cheng, Fang-Yuan Mao, Yong-Sheng Teng, Liu-Sheng Peng, Jin-Yu Zhang, Ya-Ling Liao, Shi-Ming Yang, Yong-Liang Zhao, Weisan Chen, Quan-Ming Zou, Yuan Zhuang   +23 more
doaj   +1 more source

Angiopoietin-like 4 directs uptake of dietary fat away from adipose during fasting

Molecular Metabolism, 2017
Objective: Angiopoietin-like 4 (ANGPTL4) is a fasting-induced inhibitor of lipoprotein lipase (LPL) and a regulator of plasma triglyceride metabolism. Here, we examined the kinetics of Angptl4 induction and tested the hypothesis that ANGPTL4 functions ...
Emily M. Cushing, Xun Chi, Kelli L. Sylvers, Shwetha K. Shetty, Matthew J. Potthoff, Brandon S.J. Davies   +5 more
doaj   +1 more source

Hypocholesterolemia in liver and cardiovascular disease: Friend or foe?

Journal of Internal Medicine, EarlyView.
Abstract Hypocholesterolemia is perceived as benign given its association with lower cardiovascular risk. However, genetic and epidemiological evidence indicates that persistently low levels of low‐density lipoprotein cholesterol (LDL‐C) and apolipoprotein B (ApoB) arise from distinct biological mechanisms with different hepatic implications ...
Valentina Flagiello, Emelie Barreby, Umberto Vespasiani‐Gentilucci, Stefano Romeo   +3 more
wiley   +1 more source

Characterization of ANGPTL4 function in macrophages and adipocytes using Angptl4-knockout and Angptl4-hypomorphic mice

, 2019
ANGPTL4 regulates plasma lipids, making it an attractive target for correcting dyslipidemia. However, ANGPTL4 inactivation in mice fed a high fat diet causes chylous ascites, an acute-phase response, and mesenteric lymphadenopathy.
Kersten, A.H., Olivecrona, Gunilla, Ruppert, P.M.M., Boutens, L., Oteng, A.B., Stienstra, R., Dierendonck, X.A.M.H., van, Dijk, Wieneke   +7 more
core  

Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue [PDF]

, 2012
Background - Lipoprotein lipase (LPL) hydrolyzes triglycerides in lipoproteins and makes fatty acids available for tissue metabolism. The activity of the enzyme is modulated in a tissue specific manner by interaction with other proteins.
Kersten, Sander,, Stienstra, R., Rinke Stienstra, Olivecrona, Thomas,, Mattijssen, Frits,, Sukonina, Valentina,, Stefan K Nilsson, Olivecrona, Gunilla,, Olessia Kroupa, Olivecrona, G., Vorrsjö, E., Stienstra, Rinke,, Kersten, A.H., Evelina Vorrsjö, Gunilla Olivecrona, Frits Mattijssen, Sander Kersten, Valentina Sukonina, Thomas Olivecrona, Nilsson, S.K., Sukonina, V., Olessia Kroupa, Nilsson, Stefan K,, Mattijssen, F.B.J., Kroupa, O., Kroupa, Olessia,, Vorrsjö, Evelina,   +26 more
core   +1 more source

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Immunohistochemical staining of ANGPTL4.

, 2019
ANGPTL4 staining (brown) at the wound site immediately (day0) after wounding, and at days 1, 2, 3, 7 and 14 after wounding. Images are representative of n = 3.
Natalia Vapniarsky (307268), Chrisoula A. Toupadakis (7378214), Alice Wong (629867), Clare E. Yellowley (7378211)   +3 more
core   +1 more source

Adaptations of glucagon‐like peptide‐1 receptor agonist‐induced weight loss, drivers of weight regain and future directions of therapeutics

The Journal of Physiology, EarlyView.
Abstract figure legend During GLP‐1RA treatment reduced appetite and energy intake, delayed gastric emptying, decreased visceral fat mass and improved glycaemic control contribute to weight loss. After treatment cessation these benefits are partially or completely reversed, resulting in weight regain, accompanied by increased appetite and energy intake,
Camille E. M. Piguet, Rosie Nucci, Jacqueline L. Beaudry   +2 more
wiley   +1 more source

Probiotics upregulate ANGPTL4 expression in colonic cell lines.

, 2013
A) Real-time PCR of ANGPTL4 mRNA in HCT116 cells co-cultured with Lactobacillus F19 (F19; 107/ml), Bifidobacterium lactis (BB12; 107/ml) and Bacteroides thetaiotaomicron (B.theta; 107/ml) respectively for 6 h were compared to non-treated (NT) control. B)
Sven Pettersson (10594), Velmurugesan Arulampalam (361337), Joseph Rafter (259917), Janet Håkansson (361336), Ying Huang (53474), Jan-Åke Gustafsson (4846), Linda Aronsson (361334), Paolo Parini (87438), Marion Korach-André (361335)   +8 more
core   +1 more source

Fisetin Attenuates Human Macrophage Polarization and Pro‐Inflammatory Responses via NLRP3 and NF‐κB/MAPK Suppression

Cell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Natural compounds with anti‐inflammatory properties are increasingly explored as therapeutic agents due to their lower risk of side effects compared with conventional drugs. Fisetin, a dietary bioflavonol abundant in fruits and vegetables, exhibits anti‐inflammatory activity in several cell types, including murine macrophages.
Nattaya Onpan, Chanchao Lorthongpanich, Pakpoom Kheolamai, Pimjai Chingsuwanrote, Napachai Rodboon, Sudjit Luanpitpong, Chonticha Saisawang, Surapol Issaragrisil   +7 more
wiley   +1 more source