Results 81 to 90 of about 11,372 (280)

Pharmacokinetics and Tissue Distribution of Anidulafungin in Rats [PDF]

Antimicrobial Agents and Chemotherapy, 2008
ABSTRACT This study assessed the tissue distribution of anidulafungin in rats. Anidulafungin rapidly distributed into tissues, achieving peak concentrations within 30 min, and maintained levels above MICs for common pathogens over 72 h. In tissues susceptible to fungal infection (liver, lung, spleen, kidney), exposure was 9- to 12-fold higher
Martin Stogniew, Bharat Damle, James A. Dowell   +2 more
openaire   +3 more sources

Epidemiology of Candidemia, Candiduria and Emerging Candidozyma (Candida) auris Across Gulf Cooperative Council Countries and Yemen in the Arabian Peninsula

Mycoses, Volume 68, Issue 6, June 2025.
ABSTRACT Candida infections represent a major component of invasive and non‐invasive mycoses globally, including the countries in the Arabian Peninsula. In this review, we present epidemiological features and trends, clinical manifestations, species distribution, antifungal susceptibility, and outcomes available for candidemia and candiduria in six ...
Suhail Ahmad, Teun Boekhout, Abdullah M. S. Al‐Hatmi, Ahmed Al‐Harrasi, Aiah Mustafa Khateb, Fatima Al Dhaheri, Hajer Bin Shuraym, Jens Thomsen, Khaled Alobaid, Mohammad Asadzadeh, Saad J. Taj‐Aldeen, Saleh Alwasel, Wadha Alfouzan, Ziauddin Khan, Husam Salah   +14 more
wiley   +1 more source

An on-line solid phase extraction procedure for the routine quantification of caspofungin by liquid chromatography-tandem mass spectrometry [PDF]

, 2012
Background: Extensive sets of data are required to investigate the potential use of a therapeutic drug monitoring with individualization of dosage of the antimycotic compound caspofungin.
Kirchhoff, Fabian, Maier, Barbara, Ostermann, Helmut, Rieger, Christina, Spoehrer, Ute, Vogeser, Michael   +5 more
core   +1 more source

Characterization of COVID‐19‐Associated Candidemia Among Burn Patients

Journal of Clinical Laboratory Analysis, Volume 39, Issue 10, May 2025.
This study investigates the distribution of Candida species isolated from burn patients with candidemia, colonization, and urinary cultures. The findings highlight the predominance of C. albicans and C. parapsilosis across different sample types, including wound colonization, blood, and urine.
Maryam Salimi, Javad Javidnia, Azam Moslemi, Mahdi Abastabar, Mohammad Reza Mobayen, Golnar Rahimzadeh, Nahid Mirzaei Tirabadi, Seyedehzahra Nouranibaladezaei, Hassan Asghari, Behnam Sobouti, Mostafa Dahmardehei, Seyedmojtaba Seyedmousavi, Tahereh Shokohi   +12 more
wiley   +1 more source

Prescribing patterns of echinocandins in adult patients in a private hospital in Gauteng, South Africa

Southern African Journal of Infectious Diseases, 2023
Background: Worldwide, the leading cause of invasive candidiasis and the fourth leading cause of hospital-acquired infections are the Candida species (spp.) group.
Anja Grey, Rianda Joubert, Stephan Steyn, Marlene Julyan   +3 more
doaj   +1 more source

Activity of anidulafungin in a murine model of Candida krusei infection: evaluation of mortality and disease burden by quantitative tissue cultures and measurement of serum (1,3)-beta-D-glucan levels. [PDF]

, 2009
Experience with anidulafungin against Candida krusei is limited. Immunosuppressed mice were injected with 1.3 x 10(7) to 1.5 x 10(7) CFU of C. krusei.
Chen, Enuo, Ostrosky-Zeichner, Luis, Paetznick, Victor L, Rodriguez, Jose, Sheehan, Daniel J   +4 more
core  

Candida vulturna, the Next Fungal Menace? A Narrative Review

Mycoses, Volume 68, Issue 5, May 2025.
ABSTRACT Introduction The yeast Candida vulturna is a member of the Candida haemulonii species complex, like its close relative Candida auris. Members of this species complex, including C. vulturna, often display reduced susceptibility to one or more antifungal classes. Human invasive infections by C.
Ritika Harchand, Bram Spruijtenburg, Eelco F. J. Meijer, Theun de Groot, Shivaprakash M. Rudramurthy, Jacques F. Meis   +5 more
wiley   +1 more source

Invasive Fungal Disease Associated With Targeted Agents for Acute Myeloid Leukaemia: A Systematic Review

eJHaem, Volume 6, Issue 2, April 2025.
ABSTRACT Objective To examine the incidence of invasive fungal disease (IFD) in patients receiving targeted agents for acute myeloid leukaemia (AML). Methods Literature for this systematic review was identified through a PubMed search in April 2024, using AML, IFD and targeted therapy terms.
Samir Agrawal, Anjaneya Bapat, Christopher P. Eades, Shreyans Gandhi   +3 more
wiley   +1 more source

Suramin, Penciclovir and Anidulafungin bind nsp12, which governs the RNA-dependent-RNA polymerase activity of SARS-CoV-2, with higher interaction energy than Remdesivir, indicating potential in the treatment of Covid-19

, 2020
Structured abstract:Introduction: COVID-19, for which no vaccine or confirmed therapeutic agents are available, has claimed over 7,30,000 lives globally.
S. Dey, M. Saini, Chetna Dhembla, Shruti Bhatt, A. Rajesh, V. Anand, H. K. Das, S. Kundu   +7 more
semanticscholar   +1 more source

Bench-to-bedside review: Candida infections in the intensive care unit. [PDF]

, 2008
Invasive mycoses are life-threatening opportunistic infections and have emerged as a major cause of morbidity and mortality in critically ill patients.
Calandra, T., Marchetti, O., Méan, M.
core   +3 more sources