Results 81 to 90 of about 10,059 (251)
Candida auris, what do paediatricians need to know? [PDF]
, 2018 AW is supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of Aberdeen.Peer reviewedPublisher ...
Warris, Adilia
core +1 more source
Phenomenon of Dip Effect in Antifungal Susceptibility Testing of Candida tropicalis by using MIC Testing Strips against Echinocandins [PDF]
Journal of Clinical and Diagnostic ResearchMinimum Inhibitory Concentration (MIC) of an antifungal is the minimum concentration that completely inhibits the visible growth of fungi under regulated, uniform and consistent in-vitro conditions.
Sujata lall, Vivek Bhat
doaj +1 more source
Southern African Journal of Infectious Diseases, 2023 Background: Worldwide, the leading cause of invasive candidiasis and the fourth leading cause of hospital-acquired infections are the Candida species (spp.) group.
Anja Grey +3 more
doaj +1 more source
New cell wall-affecting antifungal antibiotics [PDF]
, 2013 Capítulo 9.Fungi have emerged worldwide as increasingly frequent causes of healthcare-associated infections. Invasive fungal infections can be life-threatening.
Cortés, Juan Carlos G. +2 more
core +2 more sources
Ibrexafungerp: Mechanism of Action, Clinical, and Translational Science
Clinical and Translational Science, Volume 18, Issue 9, September 2025.ABSTRACT Ibrexafungerp is a first‐in‐class triterpenoid antifungal that targets β‐(1,3)‐glucan synthase in fungal cell wall development. It is indicated for vulvovaginal candidiasis (VVC) and recurrent vulvovaginal candidiasis (RVVC) in adult and post‐menarchal pediatric females.
Adelynne H. Walley +3 more
wiley +1 more source
Pharmacokinetics of Anidulafungin in Obese and Normal-Weight Adults [PDF]
Antimicrobial Agents and Chemotherapy, 2018 ABSTRACT In 2025, approximately one out of five adults will be obese. Physiological changes associated with obesity have been shown to influence the pharmacokinetics of drugs. Anidulafungin is frequently used in critically ill patients, and to achieve optimal efficacy, it is essential that its dose is appropriate for each patient's ...
Roeland E. Wasmann +6 more
openaire +5 more sources
Pharmacokinetics of echinocandins in suspected candida peritonitis: A potential risk for resistance
International Journal of Infectious Diseases, 2020 Introduction: A possible increase in Candida resistance, especially in Candida glabrata, has been speculated according to poor diffusion of echinocandins to peritoneal fluid.
Francesca Gioia +7 more
doaj +1 more source
Extended Survival in a Dog With Disseminated Protothecosis
Journal of Veterinary Internal Medicine, Volume 39, Issue 5, September/October 2025.ABSTRACT A 5‐year‐old Basenji Mix achieved extended survival with treatment for disseminated protothecosis. The dog originally presented with iridal hyperemia and ocular ultrasonographic examination revealed a mass effect. Histopathology revealed ocular protothecosis and staging confirmed disseminated protothecosis.
Bianca G. Landfield +5 more
wiley +1 more source
Recent Insights into the Paradoxical Effect of Echinocandins
Journal of Fungi, 2017 Echinocandin antifungals represent one of the most important drug classes for the treatment of invasive fungal infections. The mode of action of the echinocandins relies on inhibition of the β-1,3-glucan synthase, an enzyme essentially required for the ...
Johannes Wagener, Veronika Loiko
doaj +1 more source
Mycoses, Volume 68, Issue 9, September 2025.ABSTRACT Introduction Candidaemia is a life‐threatening infection with a persistently high mortality rate, despite significant advances in antifungal therapy and supportive care. The European Confederation of Medical Mycology developed the EQUAL Candida Score as a standardised tool to evaluate adherence to guideline‐based management; however, its ...
Elif Mukime Saricaoglu +9 more
wiley +1 more source