Results 41 to 50 of about 2,702,428 (250)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A freshwater diet-derived 14C reservoir effect at the Stone Age sites in the Iron Gates gorge [PDF]

, 2001
Human bones from single inhumation burials and artifacts made from terrestrial mammal (ungulate) bone found in direct association with the skeletons were obtained from the Stone Age site of Schela Cladovei situated just below the Iron Gates Gorge of the ...
McSweeney, Kathleen, Hedges, Robert, Pettitt, Paul B., Bonsall, C., Boroneanț, Vasile, Cook, Gordon, Pettitt, Paul, Bonsall, Clive, Hedges, Robert E. M., Cook, Gordon T., McSweeney, K., Boronean, V.   +11 more
core   +1 more source

Nitrogen isotopic fractionation as a biomarker for nitrogen use efficiency in ruminants: a meta-analysis

Animal, 2018
Animal proteins are naturally 15N enriched relative to the diet and the extent of this difference (Δ15Nanimal-diet or N isotopic fractionation) has been correlated to N use efficiency (NUE; N gain or milk N yield/N intake) in some recent ruminant studies.
G. Cantalapiedra-Hijar, R.J. Dewhurst, L. Cheng, A.R.J. Cabrita, A.J.M. Fonseca, P. Nozière, D. Makowski, H. Fouillet, I. Ortigues-Marty   +8 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Environmental Life Cycle Assessment of Diets with Improved Omega-3 Fatty Acid Profiles. [PDF]

PLoS ONE, 2016
A high incidence of cardiovascular disease is observed worldwide, and dietary habits are one of the risk factors for these diseases. Omega-3 polyunsaturated fatty acids in the diet help to prevent cardiovascular disease.
Carla R V Coelho, Franck Pernollet, Hayo M G van der Werf   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Asian-Australasian Journal of Animal Sciences

, 2009
Two metabolism trials were conducted with 24 wether lambs to investigate the effects of feeding crab meal and other protein supplements on N utilization, digestibility and Ca and P balance in sheep. The lambs (avg.
Viswanathan, T. V., Fontenot, Joseph P.
core   +1 more source

Dinâmica da composição botânica da dieta selecionada por bovinos em uma pastagem cultivada em área de várzea = Dynamic of the botanical composition of the diet selected by cattle grazing on a lowland cultivated pasture

Acta Scientiarum: Animal Sciences, 2006
Três hectares de várzea, situados no Campus da Universidade Federal de Santa Maria, Estado do Rio Grande do Sul (Brasil), foram cultivados com Lolium multiflorum Lam.
Jumaida Maria Rosito, Enio Marchezan, Fernando Luiz Ferreira de Quadros, Duílio Guerra Bandinelli, Carla Maria Garlet de Pelegrin   +4 more
doaj  

Spontaneously Diabetic Torii Fatty Rat Shows Early Stage of Diabetic Retinopathy Characterized by Capillary Changes and Inflammation

Journal of Diabetes Research
Conclusions: Our study demonstrated that the SDT fatty rats exhibited early diabetic retinal changes, suggesting that the SDT fatty rats may be useful in research on the pathogenesis of early human diabetic retinopathy.
Kasumi Kikuchi, Miyuki Murata, Yasushi Kageyama, Masami Shinohara, Tomohiko Sasase, Kousuke Noda, Susumu Ishida   +6 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source