Results 111 to 120 of about 9,634,082 (235)
Development of the G3 Designed ankyrin repeat protein (DARPin) for HER2 imaging
, 2015 Background: Human epidermal growth factor receptor-2 (HER2) expression predicts response to anti-HER2 therapy in breast and gastric cancer. HER2 status is assessed by tumour biopsy but this may not be representative of the larger tumour mass or other ...
Goldstein, RM
core
Immunoblot and immunofluorescent detection of ankyrin-G isoforms in heart.
, 2015 (A) Ankyrin-G immunoblot demonstrates expression of different isoforms in heart (arrows). Loss of ankyrin-G immunoreactive polypeptides in ankyrin-G null cerebellums demonstrates antibody specificity.
Henry C. Wu (747120) +3 more
core +1 more source
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
De novo TANC2 stop‐loss variant associated with developmental impairment and drug‐resistant epilepsy
Epileptic Disorders, EarlyView.
Matthew A. Hintermayer, Kenneth A. Myers
wiley +1 more source
New Plant Protection, EarlyView.This review highlights how Phytophthora sojae utilizes unconventional lineage‐specific signaling networks, including unique G protein‐coupled receptor fusions, expanded kinases, and rapidly evolving effectors, to infect soybeans. Understanding these divergent molecular paradigms reveals critical vulnerabilities in this destructive pathogen, offering ...
Min Qiu +4 more
wiley +1 more source
Human Ankyrin-B E1425G Mutation Abolishes Binding to NKA, NCX1, and InsP3R
, 2013 (A) 220-kDa ankyrin-B domain organization. The human LQT4 E1425G mutation is marked. (B) Immunoblot of expressed wild-type and mutant GFP-ankyrin-B proteins. (C–E) Relative binding of rat heart lysate (C) InsP3R, (D) NCX1, and (E)
Vann Bennett (12418) +2 more
core +1 more source
New Plant Protection, EarlyView.We developed a transient expression system for sugarcane using Guitang 42 culm, suitable for various assays such as GCaMP6‐based calcium imaging. This system revealed that ScNCED3 acts as an early drought response signal, positively regulated by ScPYL4‐12, ScOST1‐12, and ScMPK6‐11.
Dianqi Wu +10 more
wiley +1 more source
PLoS Biology, 2019 [This corrects the article DOI: 10.1371/journal.pbio.3000311.].
Rudo Simeon +10 more
doaj +1 more source
Russian wheat aphid: a model for genomic plasticity and a challenge to breeders
Insect Science, EarlyView.Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn +8 more
wiley +1 more source
Immunolocalization of ankyrin-G in 5 day IZ (panel A) and Remote cells (panel B).
, 2013 The altered ankyrin-G staining appears to increase in signal just below membrane in IZ. Panel C: Ratio of surface/core of ankyrin-G staining measured in IZ and Remote. Open symbols: individual measurements.
Patrick Wright (470353) +5 more
core +1 more source