Results 91 to 100 of about 8,763 (208)

Coupled cluster calculations of the vertical excitation energies of tetracyanoethylene [PDF]

open access: yes, 2003
Coupled cluster linear-response formalism has been used to compute the vertical spectrum of ethylene and tetracyanoethylene (TCNE). We show that for both molecules the ππ∗ excitation 1A1g→1B1u of the experimental spectrum is not vertical nor the 0-0 ...
García Cuesta, Inmaculada   +2 more
core   +2 more sources

TMEM92 shields DDX3X from TTC3‐mediated degradation to confer chemoresistance in triple‐negative breast cancer

open access: yesClinical and Translational Medicine, Volume 16, Issue 5, May 2026.
TMEM92 protects DDX3X from degradation by the E3 ligase TTC3, promoting TNBC cell proliferation and tumour growth. Depleting TMEM92 not only suppresses tumour growth but also sensitises cells to cisplatin, suggesting that targeting this axis is a potential therapeutic strategy.
Hao Shen   +12 more
wiley   +1 more source

High ANO1 expression is a prognostic factor and correlated with an immunosuppressive tumor microenvironment in pancreatic cancer

open access: yesFrontiers in Immunology
BackgroundAminooctylamine (ANO1) plays an oncogenic role in various cancers. However. its role in pancreatic cancer (PC) has rarely been studied. This study investigated the prognostic value of ANO1 and its correlation with the tumor microenvironment ...
Guangnian Zhang   +12 more
doaj   +1 more source

ER localized bestrophin1 activates Ca2+ dependent ion channels TMEM16A and SK4 [PDF]

open access: yes, 2009
Bestrophins form Ca2+ activated Cl- channels and regulate intercellular Ca2+ signaling1. We demonstrate that bestrophin 1 is localized in the endoplasmic reticulum (ER), where it physically interacts with stromal interacting molecule 1 (Stim1), the ER ...
Fadi AlDehni   +6 more
core   +2 more sources

Mechanobiology in Stem Cell‐Based Bioprinting

open access: yesCell Proliferation, Volume 59, Issue 5, May 2026.
Mechanobiology in stem cell‐based bioprinting is an emerging field that bridges the mechanical conditions of the bioprinting process with the regulation of stem cell behaviour for engineering living tissues. Stresses encountered during bioprinting, together with the mechanical properties of bioinks, play a critical role in regulating stem cell ...
Supeng Ding, Tiankun Liu, Rui Yao
wiley   +1 more source

Livro explicativo do Programa Nacional de Avaliação Externa da Qualidade - PNAEQ 2016 [PDF]

open access: yes, 2015
Desde 1978 que o Programa Nacional de Avaliação Externa da Qualidade (PNAEQ) é uma das atribuições do Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA, I.P.).
Brito, Cristina   +3 more
core  

Testing High Dimensional Covariance Matrices, with Application to Detecting Schizophrenia Risk Genes

open access: yes, 2016
Scientists routinely compare gene expression levels in cases versus controls in part to determine genes associated with a disease. Similarly, detecting case-control differences in co-expression among genes can be critical to understanding complex human ...
Devlin, Bernie   +3 more
core   +1 more source

Cells and ionic conductances contributing to spontaneous activity in bladder and urethral smooth muscle

open access: yesThe Journal of Physiology, Volume 604, Issue 9, Page 3611-3632, 1 May 2026.
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm   +3 more
wiley   +1 more source

Activation and inhibition of TMEM16A calcium-activated chloride channels. [PDF]

open access: yesPLoS ONE, 2014
Calcium-activated chloride channels (CaCC) encoded by family members of transmembrane proteins of unknown function 16 (TMEM16) have recently been intensely studied for functional properties as well as their physiological roles as chloride channels in ...
Yu-Li Ni, Ai-Seon Kuan, Tsung-Yu Chen
doaj   +1 more source

TMEM16A Contributes to Calcium‐Activated Chloride Currents and Membrane Potential Changes in the Mouse Oocyte

open access: yesJournal of Cellular Physiology, Volume 241, Issue 3, March 2026.
ABSTRACT Oscillations in intracellular Ca2+ [Ca2+]i are essential for mouse oocyte activation following fertilization. These [Ca2+]i oscillations also induce repetitive hyperpolarizations in the membrane potential (Em). The present study aimed to identify the channels underlying the Em hyperpolarizations.
Sarah Dalati   +2 more
wiley   +1 more source

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