Results 91 to 100 of about 8,763 (208)
Coupled cluster calculations of the vertical excitation energies of tetracyanoethylene [PDF]
Coupled cluster linear-response formalism has been used to compute the vertical spectrum of ethylene and tetracyanoethylene (TCNE). We show that for both molecules the ππ∗ excitation 1A1g→1B1u of the experimental spectrum is not vertical nor the 0-0 ...
García Cuesta, Inmaculada +2 more
core +2 more sources
TMEM92 protects DDX3X from degradation by the E3 ligase TTC3, promoting TNBC cell proliferation and tumour growth. Depleting TMEM92 not only suppresses tumour growth but also sensitises cells to cisplatin, suggesting that targeting this axis is a potential therapeutic strategy.
Hao Shen +12 more
wiley +1 more source
BackgroundAminooctylamine (ANO1) plays an oncogenic role in various cancers. However. its role in pancreatic cancer (PC) has rarely been studied. This study investigated the prognostic value of ANO1 and its correlation with the tumor microenvironment ...
Guangnian Zhang +12 more
doaj +1 more source
ER localized bestrophin1 activates Ca2+ dependent ion channels TMEM16A and SK4 [PDF]
Bestrophins form Ca2+ activated Cl- channels and regulate intercellular Ca2+ signaling1. We demonstrate that bestrophin 1 is localized in the endoplasmic reticulum (ER), where it physically interacts with stromal interacting molecule 1 (Stim1), the ER ...
Fadi AlDehni +6 more
core +2 more sources
Mechanobiology in Stem Cell‐Based Bioprinting
Mechanobiology in stem cell‐based bioprinting is an emerging field that bridges the mechanical conditions of the bioprinting process with the regulation of stem cell behaviour for engineering living tissues. Stresses encountered during bioprinting, together with the mechanical properties of bioinks, play a critical role in regulating stem cell ...
Supeng Ding, Tiankun Liu, Rui Yao
wiley +1 more source
Livro explicativo do Programa Nacional de Avaliação Externa da Qualidade - PNAEQ 2016 [PDF]
Desde 1978 que o Programa Nacional de Avaliação Externa da Qualidade (PNAEQ) é uma das atribuições do Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA, I.P.).
Brito, Cristina +3 more
core
Testing High Dimensional Covariance Matrices, with Application to Detecting Schizophrenia Risk Genes
Scientists routinely compare gene expression levels in cases versus controls in part to determine genes associated with a disease. Similarly, detecting case-control differences in co-expression among genes can be critical to understanding complex human ...
Devlin, Bernie +3 more
core +1 more source
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm +3 more
wiley +1 more source
Activation and inhibition of TMEM16A calcium-activated chloride channels. [PDF]
Calcium-activated chloride channels (CaCC) encoded by family members of transmembrane proteins of unknown function 16 (TMEM16) have recently been intensely studied for functional properties as well as their physiological roles as chloride channels in ...
Yu-Li Ni, Ai-Seon Kuan, Tsung-Yu Chen
doaj +1 more source
ABSTRACT Oscillations in intracellular Ca2+ [Ca2+]i are essential for mouse oocyte activation following fertilization. These [Ca2+]i oscillations also induce repetitive hyperpolarizations in the membrane potential (Em). The present study aimed to identify the channels underlying the Em hyperpolarizations.
Sarah Dalati +2 more
wiley +1 more source

