Results 91 to 100 of about 3,792 (162)
ANO1 inhibits cardiac fibrosis after myocardial infraction via TGF-β/smad3 pathway
Scientific Reports, 2017 As a newly identified factor in calcium-activated chloride channel, ANO1 participates in various physiological processes like proliferation and differentiation, and expresses in human cardiac fibroblasts.
Yao Gao +5 more
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Anoctamin-1 affects the migration and invasion of anaplastic thyroid carcinoma cells
Animal Cells and Systems, 2019 Anaplastic thyroid carcinoma (ATC) is a rare malignancy with very poor prognosis. The exact cause underlying its strong aggressive nature is not clear.
Jae-Young Kim +7 more
doaj +1 more source
A Cftr-independent, Ano1-rich seawater-adaptive ionocyte in sea lamprey gills
The authors thank A. Weinstock, S. Banerjee, Y. Yamaguchi, A. Daigle, H. Kerr, E. Walton and R. Pelis for their help in animal collection, experimentation, tissue sampling, molecular/bioinformatic analyses or interpretation of our data.
Breves, Jason P. +8 more
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Frontiers in Physiology, 2017 Circadian rhythms are essential for health and regulate various physiological functions. These rhythms are regulated by a negative-feedback loop involving clock genes in the suprachiasmatic nucleus (SCN) and peripheral tissues.
Ryouichi Satou +6 more
doaj +1 more source
Scientific ReportsDespite growing evidence implicating the calcium-activated chloride channel anoctamin1 (ANO1) in cancer metastasis, its direct impact on the metastatic potential of prostate cancer and the possible significance of epigenetic alteration in this process ...
Yonghwan Shin, Sungmin Kim, Woojin An
doaj +1 more source
Suppression of 14-3-3gamma-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells [PDF]
, 2016 Anoctamin-1 (ANO1) acts as a Ca(2+)-activated Cl(-) channel in various normal tissues, and its expression is increased in several different types of cancer.
Lee, SG +14 more
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Patch-clamp analysis of ANO1 inhibition by Ani9 in FRT-ANO1 cells.
, 2016 A) Whole-cell ANO1 current was recorded at a holding potential at 0 mV and was pulsed to voltages between ± 100 mV (in steps of 20 mV) in the absence and presence of 50 nM, 100 nM and 1 μM Ani9. ANO1 was activated by 100 μM ATP.
Jinhong Park (161037) +6 more
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PCR for Ano1, Ano8, and tweety3 in different neuronal tissues.
, 2012 Representative PCR for Ano1, Ano8, and tweety3 on adult and newborn mouse TG, and adult mouse DRG and brain tissue. Ano1, 8: anoctamin1, 8, Ttyth3: protein tweety homolog 3, Gapdh: glyceraldehyde-3-phosphate dehydrogenase, Actb: actin, cytoplasmic 1.
Nicole Schöbel (120873) +11 more
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Low dose cadmium exposure regulates miR-381–ANO1 interaction in airway epithelial cells
Scientific ReportsChronic obstructive pulmonary disease (COPD) is the 3rd leading cause of death worldwide. Cigarette smoke which has approximately 2–3 µg of Cadmium (Cd) per cigarette contributes to the environmental exposure and development and severity of COPD.
Pooja Singh +7 more
doaj +1 more source
The putative reentrant loop domain of ANO1 facilitates channel activation
, 2012 The calcium-activated chloride channel ANO1 (TMEM16A) regulates multiple physiological processes, including fluid secretion, smooth muscle constriction and neuronal excitability.
Groot Kormelink, Paul +4 more
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