Results 31 to 40 of about 29,991,200 (152)
, 2012 We investigated the cellular distribution of the calcium-activated chloride channel (CaCC), anoctamin 1, in the urethra of mice, rats, and sheep by both immunofluorescence and PCR. We studied its role in urethral contractility by examining the effects of
Sancho González, María +2 more
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MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology
Nature Communications, 2017 Downregulation of the anoctamin 1 calcium channel in airway epithelial cells contributes to pathology in cystic fibrosis. Here the authors show that microRNA-9 targets anoctamin 1 and that inhibiting this interaction improves mucus dynamics in mouse ...
Florence Sonneville +7 more
doaj +1 more source
Generation of Muscle Tone in the Murine Internal Anal Sphincter by Anoctamin 1 [PDF]
, 2015 The University of Nevada, Reno Libraries will promptly respond to removal requests related to content that violates intellectual property laws, data protections, or has been uploaded without creator consent.
Kirchoff, Ileah
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Chloride – The Underrated Ion in Nociceptors
Frontiers in Neuroscience, 2020 In contrast to pain processing neurons in the spinal cord, where the importance of chloride conductances is already well established, chloride homeostasis in primary afferent neurons has received less attention.
Bettina U. Wilke +3 more
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Mechanical Stress Modulates Calcium-Activated-Chloride Currents in Differentiating Lens Cells
Frontiers in Physiology, 2022 During accommodation, the lens changes focus by altering its shape following contraction and relaxation of the ciliary muscle. At the cellular level, these changes in shape may be accompanied by fluid flow in and out of individual lens cells.
Lisa Ebihara +3 more
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Differential expression of anoctamin 1 in human epithelial ovarian cancer.
, 2021 Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published and public microarray data (2,
Shahan Mamoor
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Paneth Cell Secretion in vivo Requires Expression of Tmem16a and Tmem16f
Gastro Hep Advances, 2022 Background and Aims: Paneth cells play a central role in intestinal innate immune response. These cells are localized at the base of small intestinal crypts of Lieberkuhn.
Rainer Schreiber +2 more
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Validation of splice altering morpholino knockdown of anoctamin 1 [PDF]
, 2015 Morpholino oligonucleotides (MO) are commonly used to reduce gene expression. MO selectivity is determined by selection of a unique oligonucleotide sequence in the target of interest Suitable targets for splice altering MO are at an intron-exon ...
Denora, Maxwell
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Cells, 2020 TMEM16A/anoctamin1 (ANO1), a calcium (Ca2+)-activated chloride (Cl−) channel, has many functions in various excitable cells and modulates excitability in both Ca2+- and voltage-gating modes.
Sun-Sook Paik +2 more
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Regulation of TMEM16A by CK2 and Its Role in Cellular Proliferation
Cells, 2020 Casein kinase 2 (CK2) is a highly ubiquitous and conserved serine/threonine kinase that forms a tetramer consisting of a catalytic subunit (CK2α) and a regulatory subunit (CK2β). Despite being ubiquitous, CK2 is commonly found at higher expression levels
Madalena C. Pinto +6 more
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