Results 91 to 100 of about 20,389 (266)

A d-Amino Acid at the N-Terminus of a Protein Abrogates Its Degradation by the N-End Rule Pathway [PDF]

open access: yes, 2015
Eukaryotes have evolved the ubiquitin (Ub)/proteasome system to degrade polypeptides. The Ub/proteasome system is one way that cells regulate cytosolic protein and amino acids levels through the recognition and ubiquitination of a protein’s N-terminus ...
Pentelute, Bradley L., Rabideau, Amy
core   +3 more sources

Cardiac-specific catalase overexpression rescues anthrax lethal toxin-induced cardiac contractile dysfunction: role of oxidative stress and autophagy

open access: yesBMC Medicine, 2012
Background Lethal and edema toxins secreted by Bacillus anthracis during anthrax infection were found to incite serious cardiovascular complications.
Kandadi Machender R   +3 more
doaj   +1 more source

The unfolding story of anthrax toxin translocation [PDF]

open access: yesMolecular Microbiology, 2011
SummaryThe essential cellular functions of secretion and protein degradation require a molecular machine to unfold and translocate proteins either across a membrane or into a proteolytic complex. Protein translocation is also critical for microbial pathogenesis, namely bacteria can use translocase channels to deliver toxic proteins into a target cell ...
Katie L. Thoren, Bryan A. Krantz
openaire   +3 more sources

The Role of Foxes in Transmitting Zoonotic Bacteria to Humans: A Scoping Review

open access: yesZoonoses and Public Health, Volume 72, Issue 6, Page 485-500, September 2025.
ABSTRACT Zoonotic diseases inflict substantial burdens on human and animal populations worldwide, and many of these infections are bacterial. An Australian study investigating environmental risk factors for Buruli ulcer in humans detected the causative agent, Mycobacterium ulcerans , in the faeces of wild foxes, a novel finding that suggests foxes may ...
Emma C. Hobbs   +6 more
wiley   +1 more source

Integrating Citizen Science and Remote Sensing Data to Identify Key Environmental Factors Influencing H5N1 Avian Influenza Virus Potential Spillover Risk in the Philippines

open access: yesGeoHealth, Volume 9, Issue 8, August 2025.
Abstract Highly pathogenic avian influenza (HPAI) virus presents a serious threat to poultry and public health worldwide, with transmission dynamics shaped by avian migration patterns and environmental conditions. Recent outbreaks in the Philippines highlight the urgent need for effective control measures.
John Oliver Sayseng, Ting‐Wu Chuang
wiley   +1 more source

Contribution of toxins to the pathogenesis of inhalational anthrax [PDF]

open access: yesCellular Microbiology, 2007
Inhalational anthrax is a life-threatening infectious disease of considerable concern, especially as a potential bioterrorism agent. Progress is gradually being made towards understanding the mechanisms used by Bacillus anthracis to escape the immune system and to induce severe septicaemia associated with toxaemia and leading to death.
Jean-Nicolas Tournier   +3 more
openaire   +3 more sources

Progress in Aptamer Research and Future Applications

open access: yesChemistryOpen, Volume 14, Issue 7, July 2025.
This paper mainly describes the screening method of aptamer, the screening difficulties and improvement methods of small molecule aptamer, and the application and treatment of aptamer. It explores the latest progress and application of aptamers, and summarises them, thus indicating some problems that still exist in this field.
Song Liu   +4 more
wiley   +1 more source

The Role of Scientific Discovery in the Establishment of the First Biological Weapons Programmes [PDF]

open access: yes, 2005
YesThis report addresses the scientific and technological discoveries in the biological sciences that enabled the early interest in biological warfare to move from hurling infected corpses into enemy cities in ancient times, through use of small cultures
Davison, N.
core  

Anthrax toxin takes charge

open access: yesThe Journal of Cell Biology, 2003
Bacterial toxin proteins are generally thought to enter eukaryotic cells by passive hitchhiking, binding to a convenient receptor that is constitutively internalized by endocytosis to ensure their delivery to the cytoplasm. But on page 321, Abrami et al.
openaire   +3 more sources

Evaluating Feed Utilization and Growth of Washera Sheep Supplemented Chamaecytisus palmensis Leaves and Wheat Bran Mixture to a Basal Diet of Avena sativa Straw

open access: yesVeterinary Medicine and Science, Volume 11, Issue 4, July 2025.
Evaluating feed utilization and growth of Washera sheep supplemented Chamaecytisus palmensis leaves and wheat bran mixture to a basal diet of Avena sativa straw. After a 3‐month feeding experiment, sheep in T4 showed the highest body weight gain, which in turn resulted in the highest net return.
Mulusew Tadege   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy