Results 91 to 100 of about 9,869 (220)
Anthrax lethal toxin exerts potent metabolic inhibition of the cardiovascular system
mBioBacillus anthracis causes anthrax through a combination of bacterial infection and toxemia. As a major virulence factor of B. anthracis, anthrax lethal toxin (LT) is a zinc-dependent metalloproteinase, exerting its cytotoxicity through proteolytic ...
Jie Liu +5 more
doaj +1 more source
Cytoskeleton as an Emerging Target of Anthrax Toxins
Toxins, 2012 Bacillus anthracis, the agent of anthrax, has gained virulence through its exotoxins produced by vegetative bacilli and is composed of three components forming lethal toxin (LT) and edema toxin (ET).
Jean-Nicolas Tournier, Yannick Trescos
doaj +1 more source
The Journal of Cell Biology, 2003 Bacterial toxin proteins are generally thought to enter eukaryotic cells by passive hitchhiking, binding to a convenient receptor that is constitutively internalized by endocytosis to ensure their delivery to the cytoplasm. But on page 321, Abrami et al.
openaire +2 more sources
Raxibacumab: potential role in the treatment of inhalational anthrax
Infection and Drug Resistance, 2014 Carlos E KummerfeldtDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, Medical University of South Carolina, Charleston, SC, USAAbstract: Anthrax is a highly contagious and potentially fatal human disease caused by Bacillus anthracis, an ...
Kummerfeldt CE
doaj
BMC Infectious Diseases, 2018 Background Disease caused by Bacillus anthracis is often accompanied by high mortality primarily due to toxin-mediated injury. In the early disease course, anthrax toxins are secreted; thus, antibiotic use is limited to the early stage.
Qi Tang +7 more
doaj +1 more source
Endothelial anthrax toxin receptor 2 plays a protective role in liver fibrosis. [PDF]
Front Cell Dev Biol, 2023 Huang X +7 more
europepmc +1 more source
Anthrax toxin receptor 2 mediates Bacillus anthracis killing of macrophages following spore challenge [PDF]
, 2005 David J. Banks +4 more
openalex +1 more source
Treatment of ovarian cancer with modified anthrax toxin. [PDF]
Proc Natl Acad Sci U S A, 2022 Aktories K.
europepmc +1 more source
DARPins bind their cytosolic targets after having been translocated through the protective antigen pore of anthrax toxin. [PDF]
Sci Rep, 2023 Becker L, Plückthun A.
europepmc +1 more source
Anthrax Toxin Targeting of Myeloid Cells through the CMG2 Receptor Is Essential for Establishment of Bacillus anthracis Infections in Mice [PDF]
, 2010 Shihui Liu +6 more
openalex +1 more source