Results 91 to 100 of about 20,389 (266)
A d-Amino Acid at the N-Terminus of a Protein Abrogates Its Degradation by the N-End Rule Pathway [PDF]
Eukaryotes have evolved the ubiquitin (Ub)/proteasome system to degrade polypeptides. The Ub/proteasome system is one way that cells regulate cytosolic protein and amino acids levels through the recognition and ubiquitination of a protein’s N-terminus ...
Pentelute, Bradley L., Rabideau, Amy
core +3 more sources
Background Lethal and edema toxins secreted by Bacillus anthracis during anthrax infection were found to incite serious cardiovascular complications.
Kandadi Machender R +3 more
doaj +1 more source
The unfolding story of anthrax toxin translocation [PDF]
SummaryThe essential cellular functions of secretion and protein degradation require a molecular machine to unfold and translocate proteins either across a membrane or into a proteolytic complex. Protein translocation is also critical for microbial pathogenesis, namely bacteria can use translocase channels to deliver toxic proteins into a target cell ...
Katie L. Thoren, Bryan A. Krantz
openaire +3 more sources
The Role of Foxes in Transmitting Zoonotic Bacteria to Humans: A Scoping Review
ABSTRACT Zoonotic diseases inflict substantial burdens on human and animal populations worldwide, and many of these infections are bacterial. An Australian study investigating environmental risk factors for Buruli ulcer in humans detected the causative agent, Mycobacterium ulcerans , in the faeces of wild foxes, a novel finding that suggests foxes may ...
Emma C. Hobbs +6 more
wiley +1 more source
Abstract Highly pathogenic avian influenza (HPAI) virus presents a serious threat to poultry and public health worldwide, with transmission dynamics shaped by avian migration patterns and environmental conditions. Recent outbreaks in the Philippines highlight the urgent need for effective control measures.
John Oliver Sayseng, Ting‐Wu Chuang
wiley +1 more source
Contribution of toxins to the pathogenesis of inhalational anthrax [PDF]
Inhalational anthrax is a life-threatening infectious disease of considerable concern, especially as a potential bioterrorism agent. Progress is gradually being made towards understanding the mechanisms used by Bacillus anthracis to escape the immune system and to induce severe septicaemia associated with toxaemia and leading to death.
Jean-Nicolas Tournier +3 more
openaire +3 more sources
Progress in Aptamer Research and Future Applications
This paper mainly describes the screening method of aptamer, the screening difficulties and improvement methods of small molecule aptamer, and the application and treatment of aptamer. It explores the latest progress and application of aptamers, and summarises them, thus indicating some problems that still exist in this field.
Song Liu +4 more
wiley +1 more source
The Role of Scientific Discovery in the Establishment of the First Biological Weapons Programmes [PDF]
YesThis report addresses the scientific and technological discoveries in the biological sciences that enabled the early interest in biological warfare to move from hurling infected corpses into enemy cities in ancient times, through use of small cultures
Davison, N.
core
Bacterial toxin proteins are generally thought to enter eukaryotic cells by passive hitchhiking, binding to a convenient receptor that is constitutively internalized by endocytosis to ensure their delivery to the cytoplasm. But on page 321, Abrami et al.
openaire +3 more sources
Evaluating feed utilization and growth of Washera sheep supplemented Chamaecytisus palmensis leaves and wheat bran mixture to a basal diet of Avena sativa straw. After a 3‐month feeding experiment, sheep in T4 showed the highest body weight gain, which in turn resulted in the highest net return.
Mulusew Tadege +2 more
wiley +1 more source

