Results 21 to 30 of about 9,869 (220)

Tumor Targeting and Drug Delivery by Anthrax Toxin [PDF]

Toxins, 2016
Anthrax toxin is a potent tripartite protein toxin from Bacillus anthracis. It is one of the two virulence factors and causes the disease anthrax.
Christopher Bachran, Stephen H. Leppla
doaj   +2 more sources

Anthrax toxin component, Protective Antigen, protects insects from bacterial infections. [PDF]

PLoS Pathogens, 2020
Anthrax is a major zoonotic disease of wildlife, and in places like West Africa, it can be caused by Bacillus anthracis in arid nonsylvatic savannahs, and by B. cereus biovar anthracis (Bcbva) in sylvatic rainforests.
Saleem Alameh, Gloria Bartolo, Summer O'Brien, Elizabeth A Henderson, Leandra O Gonzalez, Stella Hartmann, Christopher P Klimko, Jennifer L Shoe, Christopher K Cote, Laurence K Grill, Anastasia Levitin, Mikhail Martchenko Shilman   +11 more
doaj   +2 more sources

Converging physiological roles of the anthrax toxin receptors. [PDF]

F1000Res, 2019
Sergeeva OA, van der Goot FG.
europepmc   +3 more sources

The Anthrax Toxin Lethal Factor in Solution Does Not Have the Protein's Crystallized Structure. [PDF]

Toxins (Basel)
Rubinson KA, Kasianowicz JJ.
europepmc   +3 more sources

Seneca Valley virus attachment and uncoating mediated by its receptor anthrax toxin receptor 1. [PDF]

Proc Natl Acad Sci U S A, 2018
Cao L, Zhang R, Liu T, Sun Z, Hu M, Sun Y, Cheng L, Guo Y, Fu S, Hu J, Li X, Yu C, Wang H, Chen H, Li X, Fry EE, Stuart DI, Qian P, Lou Z, Rao Z.   +19 more
europepmc   +3 more sources

What Is Anthrax?

Pathogens, 2022
Anthrax has been feared for its high mortality in animals and humans for centuries. The etiologic agent is considered a potentially devastating bioweapon, and since 1876―when Robert Koch demonstrated that Bacillus anthracis caused anthrax―it has been ...
William A. Bower, Katherine A. Hendricks, Antonio R. Vieira, Rita M. Traxler, Zachary Weiner, Ruth Lynfield, Alex Hoffmaster   +6 more
doaj   +1 more source

Tumor endothelium marker-8 based decoys exhibit superiority over capillary morphogenesis protein-2 based decoys as anthrax toxin inhibitors. [PDF]

PLoS ONE, 2011
Anthrax toxin is the major virulence factor produced by Bacillus anthracis. The toxin consists of three protein subunits: protective antigen (PA), lethal factor, and edema factor.
Chenguang Cai, Jinjing Che, Long Xu, Qiang Guo, Yirong Kong, Ling Fu, Junjie Xu, Yuanguo Cheng, Wei Chen   +8 more
doaj   +1 more source

Evidence against a human cell-specific role for LRP6 in anthrax toxin entry. [PDF]

PLoS ONE, 2008
The role of the cellular protein LRP6 in anthrax toxin entry is controversial. Previous studies showed that LRP6 was important for efficient intoxication of human M2182 prostate carcinoma cells but other studies performed with cells from gene-knockout ...
Patricia L Ryan, John A T Young
doaj   +1 more source

A Comparison of the Adaptive Immune Response between Recovered Anthrax Patients and Individuals Receiving Three Different Anthrax Vaccines. [PDF]

PLoS ONE, 2016
Several different human vaccines are available to protect against anthrax. We compared the human adaptive immune responses generated by three different anthrax vaccines or by previous exposure to cutaneous anthrax.
Thomas R Laws, Tinatin Kuchuloria, Nazibriola Chitadze, Stephen F Little, Wendy M Webster, Amanda K Debes, Salome Saginadze, Nikoloz Tsertsvadze, Mariam Chubinidze, Robert G Rivard, Shota Tsanava, Edward H Dyson, Andrew J H Simpson, Matthew J Hepburn, Nino Trapaidze   +14 more
doaj   +1 more source

Disulfide bonds in the ectodomain of anthrax toxin receptor 2 are required for the receptor-bound protective-antigen pore to function. [PDF]

PLoS ONE, 2010
Cell-surface receptors play essential roles in anthrax toxin action by providing the toxin with a high-affinity anchor and self-assembly site on the plasma membrane, mediating the toxin entry into cells through endocytosis, and shifting the pH threshold ...
Jianjun Sun, R John Collier
doaj   +1 more source