Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis. [PDF]
J Rheumatol, 2015 Gan RW +12 more
europepmc +2 more sources
Biomarkers in Rheumatoid Arthritis: From Traditional Serology to Precision Medicine Integration [PDF]
DiagnosticsThe biomarker landscape in rheumatoid arthritis (RA) is evolving from reliance on traditional markers toward integrated, multimodal strategies enabling precision medicine approaches. To critically evaluate emerging biomarkers across serological, cellular,
Muhammad Soyfoo, Julie Sarrand
doaj +2 more sources
Anti-carbamylated protein antibody isotype pattern differs between palindromic rheumatism and rheumatoid arthritis [PDF]
Therapeutic Advances in Musculoskeletal Disease, 2020 Background: A restricted response against citrullinated peptides/proteins, with less isotype usage, has been found in palindromic rheumatism (PR) in comparison with rheumatoid arthritis (RA).
Raul Castellanos-Moreira +14 more
doaj +4 more sources
Improved RA classification among early arthritis patients with the concordant presence of three RA autoantibodies: analysis in two early arthritis clinics [PDF]
Arthritis Research & Therapy, 2019 Background The patients with RA benefit from early identification soon after the first clinical symptoms appear. The 2010 ACR/EULAR classification criteria were developed to fulfill this need and their application has been demonstrated to be effective ...
Cristina Regueiro +9 more
doaj +3 more sources
Anti-carbamylated protein antibodies: are they useful for the diagnosis of rheumatoid arthritis?
Clinical and Experimental Rheumatology, 2020 OBJECTIVES ACR/EULAR-2010 classification criteria for rheumatoid arthritis (RA) rely heavily on the presence of anti-citrullinated peptide antibody (ACPA). The role of anti-carbamylated protein antibodies (anti-CarP) in this context is uncertain.
F. Ponchel +6 more
semanticscholar +3 more sources
Frontiers in Immunology, 2021 To identify the targets recognized by anti-carbamylated protein antibodies (anti-CarP) in patients with early Rheumatoid Arthritis (RA), to study the cross-reactivity between anti-CarP and anti-citrullinated protein antibodies (ACPA) and to evaluate ...
Pauline Brevet +16 more
doaj +1 more source
Lupus, 2018 Objective Several studies have evaluated the prevalence of rheumatoid factor (RF) and anti-citrullinated proteins antibodies (ACPA) in systemic lupus erythematosus (SLE) patients but no data are available on the anti-carbamylated proteins (anti-CarP), a new biomarker for rheumatoid arthritis (RA).
L. Massaro +15 more
semanticscholar +4 more sources
Rheumatoid arthritis and the proinflammatory cytokine IL-17 [PDF]
Folia Medica, 2023 Introduction: Rheumatoid arthritis (RA) is the most common inflammatory joint disease. Various proinflammatory cytokines are involved in the pathogenesis of this chronic disorder.
Pavel Selimov +8 more
doaj +3 more sources
FRI0517 ANTI-CARBAMYLATED PROTEINS ANTIBODIES INDUCE OSTEOCLASTOGENESIS [PDF]
Annals of the Rheumatic Diseases, 2019 Background Post-translational-modifications (PTMs) are implicated in the pathogenesis of autoimmune diseases, leading to the break of self-tolerance, generation of new autoantigens and production of autoantibodies. Anti-citrullinated-proteins antibodies (ACPA) play a key role in the pathogenesis of rheumatoid arthritis (RA) and many evidences showed ...
Laura Massaro +16 more
openaire +1 more source
Frontiers in Immunology, 2021 Seropositive rheumatoid arthritis (RA) is characterized by the presence of rheumatoid factor (RF) and anti-citrullinated protein autoantibodies (ACPA) with different fine-specificities.
Caroline Grönwall +38 more
doaj +1 more source