Results 131 to 140 of about 15,992 (171)

Diagnostic Performance of the Multi-Biomarker Disease Activity (MBDA) Score for Rheumatoid Arthritis in Patients with New-Onset Joint Symptoms: An Age-Stratified Retrospective Study

Open Access Rheumatology: Research and Reviews
Kazuya Hiura,1 Moeko Ito,1 Yuka Shimizu,2 Tsuyoshi Takeda,3 Sachiko Iwaki-Egawa1 1Faculty of Pharmaceutical Sciences, Hokkaido University of Science, Sapporo, Japan; 2Department of Gastroenterology, Obihiro Kosei General Hospital, Obihiro, Japan ...
Hiura K, Ito M, Shimizu Y, Takeda T, Iwaki-Egawa S   +4 more
doaj  

Evolution of Anti-citrullinated Protein Antibodies in Rheumatoid Arthritis Patients Under Disease-Modifying Therapy: A Prospective Cohort Study. [PDF]

Cureus
Charoui C, Amine B, El Binoune I, Zemrani S, Rostom S, Bouziane A, Bahiri R.   +6 more
europepmc   +1 more source

The TG2/LRP1 Pathway for T Cell Activation by Post‐Translationally Modified Antigens

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Post‐translational modifications (PTMs) can generate neo‐epitopes, modified peptides that evade immune tolerance and trigger immune responses. This review focuses on the TG2/LRP1 pathway as a new paradigm for coupling the formation of post‐translationally modified peptides with their effective presentation as T‐cell antigens by dendritic cells.
Agnele Sylvia Sewa, Fu‐Chen Yang, Chaitan Khosla   +2 more
wiley   +1 more source

<i>Porphyromonas gingivalis</i> associates with the presence of anti-citrullinated protein antibodies, but not with the onset of arthritis: studies in an at-risk population. [PDF]

RMD Open
De Vries C, Cîrciumaru A, Mathsson-Alm L, Westerlind H, Dehara M, Kisten Y, Potempa B, Potempa J, Hensvold A, Lundberg K.   +9 more
europepmc   +1 more source

Increased IgA anti-citrullinated protein antibodies in the periodontal inflammatory exudate of healthy individuals compared to rheumatoid arthritis patients. [PDF]

J Clin Periodontol, 2020
Rahajoe PS, de Smit M, Schuurmans G, Raveling-Eelsing E, Kertia N, Vissink A, Westra J.   +6 more
europepmc   +1 more source

Citrullination and Deamidation in Type 1 Diabetes: Linking Beta Cell Stress to Neoantigen‐Driven Autoimmunity

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Citrullination and deamidation are post‐translational modifications (PTMs) increasingly recognized as important contributors to neoepitope formation in type 1 diabetes (T1D). Under inflammatory and endoplasmic reticulum stress conditions, beta cells activate calcium‐dependent peptidylarginine deiminase and transglutaminase enzymes, leading to ...
Aïsha Callebaut, Ylke Bruggeman, Chantal Mathieu, Eddie A. James, Lut Overbergh   +4 more
wiley   +1 more source

Association between periodontitis and anti-citrullinated protein antibodies in rheumatoid arthritis patients: a cross-sectional study. [PDF]

Arthritis Res Ther, 2020
González-Febles J, Rodríguez-Lozano B, Sánchez-Piedra C, Garnier-Rodríguez J, Bustabad S, Hernández-González M, González-Dávila E, Sanz M, Díaz-González F.   +8 more
europepmc   +1 more source

Hypoxia‐preconditioned adipose‐derived mesenchymal stem cells‐derived exosomes transferring H19 obstruct neutrophil extracellular traps formation via HOXA5‐mediated inactivation of TLR4/NF‐κB/NLRP3 inflammatory signaling

Journal of Diabetes Investigation, Volume 17, Issue 8, Page 1283-1303, August 2026.
In this study, we uncovered that Hypo‐Exo transferring H19 promoted diabetic wound healing by repressing NETs formation via the miR‐130a/b‐3p/HOXA5 pathway to inactivate the TLR4/NF‐κB/NLRP3 inflammatory signaling. ABSTRACT Background Hypoxia‐stimulated adipose‐derived mesenchymal stem cells (ADSCs)‐derived exosomes (Hypo‐Exo) have a positive impact on
Li Qian, Xianxi Meng, Bairong Fang, Li Pi   +3 more
wiley   +1 more source

The prognostic value of IgA anti-citrullinated protein antibodies and rheumatoid factor in an early arthritis population with a treat-to-target approach. [PDF]

Immunol Res
Heutz JW, Looijen AEM, Kuijpers JHSAM, Schreurs MWJ, van der Helm-van Mil AHM, de Jong PHP.   +5 more
europepmc   +1 more source

Disordered Antigens and Epitope Overlap Between Anti-Citrullinated Protein Antibodies and Rheumatoid Factor in Rheumatoid Arthritis. [PDF]

Arthritis Rheumatol, 2020
Zheng Z, Mergaert AM, Fahmy LM, Bawadekar M, Holmes CL, Ong IM, Bridges AJ, Newton MA, Shelef MA.   +8 more
europepmc   +1 more source