Impact of Anti-Citrullinated Protein Antibodies on Progressive Systemic Bone Mineral Density Loss in Patients With Early Rheumatoid Arthritis After Two Years of Treat-to-Target. [PDF]
Bugatti S +6 more
europepmc +1 more source
Abstract Objectives In this case, we present a patient with rapidly progressive unilateral destructive orbital and midface inflammation. Initial detection of Corynebacterium kroppenstedtii was followed by a consistent course of localised necrotizing small‐vessel vasculitis, which was responsive to B‐cell depletion. Methods A 79‐year‐old woman presented
Nadine Al‐Azem +11 more
wiley +1 more source
Neutrophil‐based immunotherapy: A metabolic lens on mechanisms and therapeutic implications
TAN metabolic reprogramming critically contributes to tumour immune evasion. A 4‑Tier TAN‑MetaC classification framework is proposed, along with an overview of translational opportunities and bottlenecks for TAN metabolism‑targeted immunotherapies. Abstract Background Tumor‐associated neutrophils (TANs) serve as pivotal immune modulators in the tumor ...
Wenchao Xu +4 more
wiley +1 more source
The Impact of Oral‐Gut Microbiota Structure and Its Manipulation on RA Development and Management
(A) Schematic representation of oral–gut microbiota composition in health and rheumatoid arthritis (RA), highlighting the enrichment of beneficial microorganisms (green) under healthy conditions and the expansion of pathogenic microorganisms (orange) in RA‐associated dysbiosis.
Parisa Ahmadi +8 more
wiley +1 more source
Consumed by Abdominal Distention
Arthritis Care &Research, Volume 78, Issue 8, Page 959-966, August 2026.
Abimbola Fadairo‐Azinge +3 more
wiley +1 more source
This study investigated the role of PD‐1hiCXCR5−CD4+ T peripheral helper (Tph) cells in rheumatoid arthritis (RA). Tph cells were increased in the peripheral blood of RA patients and associated with disease activity. Baseline Tph cell levels were linked to the response to etanercept therapy.
Haojie Xu +10 more
wiley +1 more source
Impact of HLA-DRB1 SE, anti-citrullinated protein antibodies and smoking on radiographic outcome in Greek patients with Rheumatoid Arthritis. [PDF]
Mole EN +7 more
europepmc +1 more source
Presence of salivary IgA anti-citrullinated protein antibodies associate with higher disease activity in patients with rheumatoid arthritis. [PDF]
Roos Ljungberg K +5 more
europepmc +1 more source
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu +10 more
wiley +1 more source
Anti-citrullinated protein antibodies may be prognostic factor for vascularization of the synovial membrane in patients with high activity of RA. [PDF]
Jakubaszek M +3 more
europepmc +1 more source

