Results 151 to 160 of about 5,182 (175)

ACPA (anti-citrullinated protein antibodies) and rheumatoid arthritis.

Acta reumatologica portuguesa, 2011
It has recently been discovered that anti-citrullinated protein antibodies (ACPA) are present in 50% of patients with early rheumatoid arthritis (RA). Assays for detecting ACPA have been shown to have very good diagnostic and predictive characteristics, and they may facilitate the identification of patients with early arthritis who need aggressive ...
Toes, R.E.M., Woude, D. van der
openaire   +3 more sources

AB0152 Low avidity anti-citrullinated protein antibodies (ACPA) are associated with enhanced radiological progression in rheumatoid arthritis

Annals of the Rheumatic Diseases, 2012
Objectives Anti-citrullinated protein antibodies (ACPA) are specific for Rheumatoid Arthritis (RA) and have been implicated in disease pathogenesis. Previously we have shown that ACPA display a considerably lower avidity as compared to antibodies against recall antigens. Nonetheless, ACPA-avidity did vary between patients. As antibody-mediated effects
A. Willemze, P. Suwannalai, K. Britsemmer, R. Knevel, H. Scherer, E. Levarht, A. van der Helm-van Mil, D. van Schaardenburg, T. Huizinga, R. Toes, L. Trouw   +10 more
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OP0268 Anti-Citrullinated Protein Antibody (ACPA) Status in the General Population and as a Predictor of Future Inflammatory Polyarthritis: The EPIC-2-Noar Study

Annals of the Rheumatic Diseases, 2015
Background Anti-citrullinated protein antibody (ACPA) immune response occurs several years prior to the diagnosis of rheumatoid arthritis (RA). However, limited data are available on ACPA status in the general population compared to those who develop RA or inflammatory polyarthritis (IP) in the future. Objectives The aim of this study was to examine
S.M. Verstappen, J.C. Sergeant, R.N. Luben, A. Bhaniani, S. Anuj, A. MacGregor, N. Wareham, D.P. Symmons, K.T. Khaw, I.N. Bruce   +9 more
openaire   +1 more source

AB1263 Higher prevalence of anti-citrullinated protein antibodies (ACPA) without impact on prognosis in patients with aggressive B-non-hodgkin lymphoma (DLCBL)

Annals of the Rheumatic Diseases, 2012
Background The complex processes of citrullination presents an ubiquitous pathophysiological procedure during inflammation. However, anti-citrullinated protein antibodies (ACPA) are highly specific for the rheumatoid arthritis (RA). In order to a variety of several autoimmune phenomenons during the course of lymphoma diseases the occurrence of ...
G. Assmann, K. Shihadeh, M.F. Ong, M. Ziepert, V. Poeschel, M. Pfreundschuh   +5 more
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Seroprevalence of Anti-Citrullinated Protein Antibodies (ACPA) in Patients with Rheumatic Diseases other than Rheumatoid Arthritis.

The Journal of the Association of Physicians of India, 2019
To evaluate the prevalence of anti- citrullinated protein antibodies (ACPA) in patients with a variety of rheumatic diseases other than rheumatoid arthritis (RA).144 cases of rheumatic diseases other than rheumatoid arthritis (RA) over a period of 1 year were recruited after consenting and followed up for 2 years.
Renu, Saigal, Surendra Singh, Bhakal, Laxmikant, Goyal, Akhil D, Goel   +3 more
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The presence of anti-citrullinated protein antibodies (ACPA) and rheumatoid factor on patients with rheumatoid arthritis (RA) does not interfere with the chance of clinical remission in a follow-up of 3 years

Rheumatology International, 2011
Autoantibodies in early rheumatoid arthritis (RA) have important diagnostic value. The association between the presence of autoantibodies against cyclic citrullinated peptide and the response to treatment is controversial. To prospectively evaluate a cohort of patients with early rheumatoid arthritis (
Licia Maria Henrique, da Mota, Leopoldo Luiz, Dos Santos Neto, Jozélio Freire, de Carvalho, Ivânio Alves, Pereira, Rufus, Burlingame, Henri A, Ménard, Ieda Maria Magalhães, Laurindo   +6 more
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AB0251 The Impact of Missing Anti-Citrullinated Protein Antibody (ACPA) Serology on Outcomes in Early Rheumatoid Arthritis: Results from Catch (Canadian Early Arthritis Cohort)

Annals of the Rheumatic Diseases, 2014
Background Anti-citrullinated protein antibody (ACPA) is a serum biomarker that is as sensitive as, but more specific than the rheumatoid factor (RF) and detected earlier in RA [1,2]. Although ACPAs are part of the ACR RA classification criteria, ACPA testing is not routinely paid for/accessible in all jurisdictions. Objectives The impact of missing
J. Shu, V. Bykerk, G. Boire, B. Haraoui, C. Hitchon, C. Thorne, D. Tin, E. Keystone, J. Pope   +8 more
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AB0227 Anti Citrullinated Protein Antibody (ACPA) in Relation to Serum Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL) and Disease Activity in Rheumatoid Arthritis

Annals of the Rheumatic Diseases, 2015
Background Bone destruction in rheumatoid arthritis (RA) remains a main concern in the clinical practice where the destructed joints may lead to impaired normal functional activity of patients. Antibodies against citrullinated proteins (ACPA) and high levels of Receptor activator of nuclear factor kappa-B ligand (RANKL) have been linked to altered ...
A.F. Elbelasy, H. Korayem, I. Khalil, M. Elsawy   +3 more
openaire   +1 more source

Anti-citrullinated protein antibodies (ACPA) and antibodies to exogenous antigens in follow-up study of rheumatoid arthritis patients

2008
Abstract not ...
MIGLIORINI, PAOLA, Anzilotti C, PRATESI, FEDERICO, Tommasi C.   +3 more
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FRI0111 Unexpected finding of anti-citrullinated protein antibodies (ACPA) in cerebrospinal fluid of RA patients with intact blood brain barrier - potential for autoimmune reactions in the CNS

Annals of the Rheumatic Diseases, 2012
Background Arthritis is known to associate with upregulation of inflammatory mediators in the central nervous system (CNS) as shown in earlier experimental studies (1). However, little is known about the possible presence of intrathecal immune activation in RA patients, which may have importance for cerebral symptoms, such as fatigue.
E. Le Maitre, K. Lundberg, E. Kosek, M. Khademi, M. Andersson, J. Lampa   +5 more
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