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Epidemiology, Impact, and Management Strategies of Anti-Glomerular Basement Membrane Disease
Muhammad Asim,1 Mohammed Akhtar2 1Division of Nephrology, Department of Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar; 2Department of Laboratory Medicine and Pathology, Hamad General Hospital, Hamad Medical Corporation, Doha ...
Asim M, Akhtar M
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病例资料患者,男,38岁,因"痰中带血1个月"于2018年7月12日入院。入院前1个月,患者无明显诱因出现暗红色血痰,量少,咳2~3口,不伴有发热、胸闷、气紧,于2018年6月7日到广元市人民医院门诊就诊,查胸部CT示双肺多发渗出灶,未予以处理。此后患者未再出现痰中带血 ...
HAO Yu, QIN Wei
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Anti-glomerular basement membrane disease mediated by IgG and IgA: a case report
Background Anti-glomerular basement membrane (anti-GBM) disease is a rare autoimmune condition responsible for rapidly progressive glomerulonephritis. This disease is usually mediated by IgG autoantibodies against the noncollagenous domain of the α3(IV ...
Guming Zou +4 more
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Atypical anti-glomerular basement membrane disease: lessons learned [PDF]
Anti-glomerular basement membrane (GBM) disease usually pursues a self-limited course, at least from the immunological perspective. In addition, circulating antibodies to cryptic, conformational epitopes within the NC1 domain of the alpha 3 chain of Type IV Collagen are commonly found at the zenith of the clinical disease.
openaire +2 more sources
An Exceptional Case of Crohn-Associated IgA-Mediated Goodpasture Disease
Anti-glomerular basement membrane (anti-GBM) disease is typically mediated by IgG autoantibodies and presents with pulmonary hemorrhage and rapidly progressive glomerulonephritis, classically referred to as Goodpasture disease.
Rebecca Ryan +4 more
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Anti–Glomerular Basement Membrane Disease: Recent Updates
Anti-glomerular basement membrane disease is a small-vessel vasculitis involving the kidneys (∼90%) and the lungs (∼60%). Antibodies against the glomerular basement membrane are directly pathogenic in anti-glomerular basement membrane disease; however, recent research has highlighted the critical role of T cells.
Joyita Bharati +3 more
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Goodpasture's syndrome with positive C-ANCA and normal renal function: A case report
Introduction Goodpasture's syndrome consists of a triad of pulmonary hemorrhage, rapidly progressive glomerulonephritis and anti-glomerular basement membrane (anti-GBM) antibodies, either in circulation or fixed to the kidney.
Ramaswami Arunachalam +6 more
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IgA mediated anti-glomerular basement membrane disease with associated circulating anti-neutrophil cytoplasm antibodies [PDF]
Anti-glomerular basement membrane (anti-GBM) disease is an aggressive small vessel vasculitis usually mediated by IgG autoantibodies. We describe the case of a 73-year-old male with rapidly progressive renal failure that was diagnosed with IgA mediated ...
Patricia Alves +4 more
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Atypical anti-glomerular basement membrane (GBM) disease is rare, and the atypical anti-GBM disease with membrane hyperplasia lesion is even rarer. The treatment plan for it is not clear.
ZHANG Xinping +2 more
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Anti-Glomerular Basement Membrane Disease With Thrombotic Thrombocytopenic Purpura
We report a 25-year-old man who was initially presented with Rapidly Progressive Glomerulonephritis (RPGN) in Shahid Modarress Hospital, Tehran, Iran.
Amirhesam Alirezaei +2 more
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