Results 21 to 30 of about 338,197 (344)
Structure-Activity Relationships of Synthetic Coumarins as HIV-1 Inhibitors
HIV/AIDS pandemics is a serious threat to health and development of mankind, and searching for effective anti-HIV agents remains actual. Considerable progress has been made in recent years in the field of drug development against HIV.
I. Kostova+3 more
doaj +2 more sources
Socially interactive agents (SIAs) are no longer mere visions for future user interfaces, as 20 years of research and technology development has enabled the use of virtual and physical agents in day-to-day interfaces and environments. This chapter of the ACM "The Handbook on Socially Interactive Agents" reviews research on and technologies involving ...
arxiv +1 more source
All opinions are not equal: Toward a consensual approach to the development of drug policy
Abstract Drug policy has been subjected to much scrutiny from different stakeholder groups who present sometimes very different opinions on solutions to address a problem. Reconciling such differences, that are underpinned by both anecdotal and empirical evidence, is a priority yet to be fully achieved.
Gabriel T. W. Wong, Matthew Manning
wiley +1 more source
Anti-HIV agents inspired by antibodies [PDF]
Emergence of drug resistance limits the efficacy of HIV drugs, which currently requires life-long administration. In vitro high-throughput screening for competition with a broadly neutralizing antibody of HIV identified a small molecule that extends the strategies for targeting HIV.
Shan Su, Shibo Jiang, Shibo Jiang
openaire +2 more sources
Abstract Introduction The inclusion of people who use drugs in the design and evaluation of their health services remains a relatively new phenomenon. The aim of the research was to explore the experiences and perceptions of people accessing the Medical Supervised Injecting Centre (MSIC), and Clinic 180, Sydney Australia, and the factors facilitating ...
Greg Rickard, Bethne Hart
wiley +1 more source
Safety of antiretrovirals in pregnacy [PDF]
nema
Dragović Gordana+5 more
doaj +1 more source
A cocktail of thermally stable, chemically synthesized capture agents for the efficient detection of anti-gp41 antibodies from human sera. [PDF]
We report on a method to improve in vitro diagnostic assays that detect immune response, with specific application to HIV-1. The inherent polyclonal diversity of the humoral immune response was addressed by using sequential in situ click chemistry to ...
Jessica A Pfeilsticker+7 more
doaj +1 more source
The Anti-HIV Actions of 7- and 10-Substituted Camptothecins
Camptothecin (CPT), a traditional anti-tumor drug, has been shown to possess anti-HIV-1 activity. To increase the antiviral potency, the anti-HIV activities of two CPT derivatives, 10-hydroxy-CPT and 7-hydroxymethyl-CPT, were evaluated in vitro.
Yu-Ye Li+5 more
doaj +1 more source
New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities [PDF]
CXCR4 is a target of growing interest for the development of new therapeutic drugs and imaging agents as its role in multiple disease states has been demonstrated.
Archibald, Stephen J.+14 more
core +1 more source
Medicinal plants used in the treatment of human immunodeficiency virus [PDF]
Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected around 70 million people worldwide, most of whom reside is sub-Saharan Africa.
A. Ata+12 more
core +1 more source