Results 21 to 30 of about 338,197 (344)

Structure-Activity Relationships of Synthetic Coumarins as HIV-1 Inhibitors

open access: yesBioinorganic Chemistry and Applications, 2006
HIV/AIDS pandemics is a serious threat to health and development of mankind, and searching for effective anti-HIV agents remains actual. Considerable progress has been made in recent years in the field of drug development against HIV.
I. Kostova   +3 more
doaj   +2 more sources

Appearance [PDF]

open access: yesIn B. Lugrin, C. Pelachaud, D. Traum (Eds.), The Handbook on Socially Interactive Agents, Volume 1 (pp. 107-146). ACM books (2021), 2021
Socially interactive agents (SIAs) are no longer mere visions for future user interfaces, as 20 years of research and technology development has enabled the use of virtual and physical agents in day-to-day interfaces and environments. This chapter of the ACM "The Handbook on Socially Interactive Agents" reviews research on and technologies involving ...
arxiv   +1 more source

All opinions are not equal: Toward a consensual approach to the development of drug policy

open access: yesAustralian Journal of Social Issues, Volume 57, Issue 4, Page 812-828, December 2022., 2022
Abstract Drug policy has been subjected to much scrutiny from different stakeholder groups who present sometimes very different opinions on solutions to address a problem. Reconciling such differences, that are underpinned by both anecdotal and empirical evidence, is a priority yet to be fully achieved.
Gabriel T. W. Wong, Matthew Manning
wiley   +1 more source

Anti-HIV agents inspired by antibodies [PDF]

open access: yesNature Chemical Biology, 2020
Emergence of drug resistance limits the efficacy of HIV drugs, which currently requires life-long administration. In vitro high-throughput screening for competition with a broadly neutralizing antibody of HIV identified a small molecule that extends the strategies for targeting HIV.
Shan Su, Shibo Jiang, Shibo Jiang
openaire   +2 more sources

Survival, safety and belonging: An ethnographic study of experiences and perceptions of people who inject drugs accessing a supervised injecting Centre

open access: yesAustralian Journal of Social Issues, Volume 57, Issue 4, Page 829-846, December 2022., 2022
Abstract Introduction The inclusion of people who use drugs in the design and evaluation of their health services remains a relatively new phenomenon. The aim of the research was to explore the experiences and perceptions of people accessing the Medical Supervised Injecting Centre (MSIC), and Clinic 180, Sydney Australia, and the factors facilitating ...
Greg Rickard, Bethne Hart
wiley   +1 more source

Safety of antiretrovirals in pregnacy [PDF]

open access: yesVojnosanitetski Pregled, 2011
nema
Dragović Gordana   +5 more
doaj   +1 more source

A cocktail of thermally stable, chemically synthesized capture agents for the efficient detection of anti-gp41 antibodies from human sera. [PDF]

open access: yesPLoS ONE, 2013
We report on a method to improve in vitro diagnostic assays that detect immune response, with specific application to HIV-1. The inherent polyclonal diversity of the humoral immune response was addressed by using sequential in situ click chemistry to ...
Jessica A Pfeilsticker   +7 more
doaj   +1 more source

The Anti-HIV Actions of 7- and 10-Substituted Camptothecins

open access: yesMolecules, 2009
Camptothecin (CPT), a traditional anti-tumor drug, has been shown to possess anti-HIV-1 activity. To increase the antiviral potency, the anti-HIV activities of two CPT derivatives, 10-hydroxy-CPT and 7-hydroxymethyl-CPT, were evaluated in vitro.
Yu-Ye Li   +5 more
doaj   +1 more source

New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities [PDF]

open access: yes, 2015
CXCR4 is a target of growing interest for the development of new therapeutic drugs and imaging agents as its role in multiple disease states has been demonstrated.
Archibald, Stephen J.   +14 more
core   +1 more source

Medicinal plants used in the treatment of human immunodeficiency virus [PDF]

open access: yes, 2018
Since the beginning of the epidemic, human immunodeficiency virus (HIV) has infected around 70 million people worldwide, most of whom reside is sub-Saharan Africa.
A. Ata   +12 more
core   +1 more source

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