Results 41 to 50 of about 338,197 (344)
New findings on the d(TGGGAG) sequence: Surprising anti-HIV-1 activity [PDF]
, 2018 The biological relevance of tetramolecular G-quadruplexes especially as anti-HIV agents has been extensively reported in the literature over the last years. In the light of our recent results regarding the slow G-quadruplex folding kinetics of ODNs based
Di Fabio, Giovanni +5 more
core +1 more source
Waking Up the Sleepers: HIV Latency and Reactivation
Journal of the Formosan Medical Association, 2008 In a patient infected with HIV-1, the presence of latently infected cells from which the virus can be reactivated and rekindle HIV infection in the patient necessitates lifelong administration of antiretroviral treatment.
Hoi Ping Mok, Andrew Lever
doaj +1 more source
HIV: Dendritic cells as embers for the infectious fire [PDF]
, 1996 In people with HIV-1, most of the CD4-expressing T cells that produce virus are short-lived and vulnerable to anti-retroviral agents. But the initial ‘fire’ of HIV-1 infection may begin in, and be maintained by, cells of the dendritic cell ...
Clark, Edward A
core +1 more source
Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein [PDF]
, 2018 In this report, we present a new benzoxazole derivative endowed with inhibitory activity against the HIV-1 nucleocapsid protein (NC). NC is a 55-residue basic protein with nucleic acid chaperone properties, which has emerged as a novel and potential ...
Botta, Maurizio +9 more
core +2 more sources
Azoles as Potent Antimicrobial Agents [PDF]
, 2019 Imidazole analogs have proved to be a very good source of medicinal agents. The various activities associated with these moieties include antibacterial, antifungal, anthelmintic, Anti HIV activity, anticancer, antihypertensive, analgesic, anti ...
Ganguly, Swastika, Singh, Rohit
core +2 more sources
Investigation of Seroprevalence of Hepatitis B, Hepatitis C and HIV in Hemodialysis Patients
Journal of Contemporary Medicine, 2021 Aim: Impairments in the immune system of patients undergoing HD cause patients to be more sensitive to infection agents. The purpose of this study; to determine the seroprevalance of HBV, HCV and HIV in patients undergoing hemodialysis treatment ...
Duygu Fındık +4 more
doaj +2 more sources
Arabian Journal of Chemistry, 2023 A growing interest in pharmacology has made heterocyclic chemistry as one of the emerging branches of organic chemistry. Piperazine is an excellent heterocycle that possesses a large span of pharmaceutical applications.
Kamran Walayat +7 more
doaj
Cooperative and Competitive Biases for Multi-Agent Reinforcement Learning [PDF]
arXiv, 2021 Training a multi-agent reinforcement learning (MARL) algorithm is more challenging than training a single-agent reinforcement learning algorithm, because the result of a multi-agent task strongly depends on the complex interactions among agents and their interactions with a stochastic and dynamic environment.
arxiv
A cytotoxic survey on 2‐amino‐1H‐imidazol based synthetic marine sponge alkaloid analogues
Drug Development Research, Volume 83, Issue 8, Page 1906-1922, December 2022., 2022 Abstract Here, we describe the synthesis and biologic activity evaluation of 20 novel synthetic marine sponge alkaloid analogues with 2‐amino‐1H‐imidazol (2‐AI) core. Cytotoxicity was tested on murine 4T1 breast cancer, A549 human lung cancer, and HL‐60 human myeloid leukemia cells by the resazurin assay.
Nikolett Gémes +10 more
wiley +1 more source
Brazilian Journal of Otorhinolaryngology, 2011 HIV is a pandemic infection with cases notified in almost all countries. The reported prevalence of symptoms in the head and neck is about 80%; otolaryngologists may be the first physician to see such patients.
Fernanda Alves Sanjar +2 more
doaj +1 more source