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The incidence of anti-HMGCR immune-mediated necrotizing myopathy: an Australian and UK retrospective multi-site cohort study

Objectives Immune-mediated necrotizing myopathy (IMNM) with autoantibodies targeting 3-hydroxy-3-methylglutaryl-CoA reductase (anti-HMGCR) is considered a rare complication of statin therapy.
Brusch, Anna, Needham, Merrilee, Buch, Maya, Khoo, Thomas, Lamb, Janine, Gunawardena, Harsha, Tomaszewski, Maciej, Tan, Elina, Austin, Kaziah, Lilleker, James, Bahadori, Aaron, Chinoy, Hector, Lyu, Xia, Sadler, Ross   +13 more
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Anti-HMGCR myopathy overlaps with dermatomyositis-like rash: a distinct subtype of idiopathic inflammatory myopathy

Journal of Neurology, 2021
Ying Hou, Gary L Norman, Yuying Zhao
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Rituximab use for refractory anti-HMGCR immune-mediated necrotizing myopathy: A case report

Intractable and Rare Diseases Research, 2021
Sonia Gupta
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Alanine transaminase is predominantly increased in the active phase of anti-HMGCR myopathy

Neuromuscular Disorders, 2022
Ran Nakashima, Tatsushi Toda, Naohiro Uchio   +2 more
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Necrotizing myopathy with elevated anti-HMGCR antibodies following exposure to the supplement Bacopa

Muscle and Nerve, 2023
Maxwell Greene, Amanda Yaworski, Andrew Lee Mammen   +2 more
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Anti-HMGCR Antibody-Positive Myopathy Shows Bcl-2-Positive Inflammation and Lymphocytic Accumulations

Journal of Neuropathology and Experimental Neurology, 2020
Tetsuya Takahashi, Hirofumi Maruyama, Takashi Kurashige   +2 more
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Anti-HMGCR myopathy following acute Epstein–Barr virus infection

Muscle and Nerve, 2020
Ichizo Nishino, Takahiro Iizuka, Naomi Kanazawa   +2 more
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Statin-associated autoimmune myopathy: A distinct new IFL pattern can increase the rate of HMGCR antibody detection by clinical laboratories

Autoimmunity Reviews, 2016
Ricardo Pujol Borrell, Ana Marín-Sánchez   +1 more
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Statin-naïve anti-HMGCR antibody-mediated necrotizing myopathy in China

Journal of Clinical Neuroscience, 2018
Wen-Hua Zhu, Chong-Bo Zhao
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Anti-HMGCR antibodies demonstrate high diagnostic value in the diagnosis of immune-mediated necrotizing myopathy following statin exposure

Immunologic Research, 2016
Miri Blank, M Mahler
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