Results 81 to 90 of about 1,968,036 (106)

ePoster

European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source

A SPONTANEOUS MOUSE MODEL OF X-LINKED MYOPATHY WITH EXCESSIVE AUTOPHAGY [PDF]

, 2011
the subject of the thesis research project, aims to characterize a murine model for spontaneous muscle pathology comparable to human "X-Linked Vacuolar myopathy with Excessive Autophagy (XMEA)".
Iovane, Valentina
core   +1 more source

Issue Information

JEADV Clinical Practice, Volume 5, Issue 1, Page 1-6, March 2026.
wiley   +1 more source

Successful corticosteroid-free management of anti-HMG–CoA reductase immune-mediated necrotizing myopathy with subcutaneous immunoglobulins monotherapy: a case report

Journal of Medical Case Reports
Background Given the high rate of cardiovascular comorbidities in anti-HMG–CoA reductase (HMGCR)–immune-mediated necrotizing myopathy (IMNM), a glucocorticosteroids (GC)-free treatment approach remains an appealing strategy.
Nikola Wilk, Juthaporn Cowan, Ronald A. Booth, Jodi Warman-Chardon, Nancy Maltez, Catherine Ivory   +5 more
doaj   +1 more source

Rare Anti-HMGCR-Induced Immune-Mediated Necrotising Myopathy: A Case Report and Literature Review

European Medical Journal
An acute necrotising myopathy is a distinct form of uncommon muscle disease characterised by the rapid advancement of weakness affecting the limbs, neck, pharyngeal, respiratory, and occasionally cardiac muscles.
Thirugnanasambandam Thayumanavan, Anjali Bhardwaj, Abhishek Bhatnagar, Shariq Shamim   +3 more
doaj   +1 more source

Myopathy due to HMGCR antibodies in adult mimicking muscular dystrophy associated with cancer and statin exposure – narrative review of the literature – case report

, 2018
Alzira Alves de Siqueira Carvalho,1 Vinicius Gomes da Silva,1 Edmar Zanoteli,2 David Feder3 1Laboratory of Neuromuscular Disease, Department of Neurosciences, School of Medicine of ABC, Santo André, São Paulo, Brazil; 2Department of ...
Zanoteli E, Silva VG, Feder D, Carvalho AAS   +3 more
core  

Immune-mediated myopathy related to anti 3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies as an emerging cause of necrotizing myopathy induced by statins

, 2014
International audienceImmune-mediated necrotizing myopathy (IMNM) associated with statin use and anti 3-hydroxy-3methylglutaryl-coenzyme A reductase (HMGCR) antibody is a new and emerging entity that supports a link between statin use and IMNM and raises
Soubrier, Martin, Beaufrére, Anne Marie, Lahaye, Clément, Drouot, Laurent, Tournadre, Anne, Boyer, Olivier   +5 more
core   +1 more source

Complement-independent pathogenic influences of anti-HMGCR + and anti-SRP + immune-mediated necrotizing myopathy autoantibodies on engineered muscle function

Skeletal Muscle
Background Immune-mediated necrotizing myopathy (IMNM) is a subgroup of idiopathic inflammatory myopathies associated with anti-signal recognition particle (SRP) or anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) autoantibodies.
Heta Lad, Yekaterina Tiper, Ernest Myguel Esteban, Manish K. Singh, Alexandrine Mahoudeau, Zhuoye Xie, Berenice Tendrel, Yves Allenbach, Olivier Benveniste, Penney M. Gilbert   +9 more
doaj   +1 more source

Absence of Pathogenic Mutations and Strong Association With HLA-DRB1∗11:01 in Statin-Naïve Early-Onset Anti-HMGCR Necrotizing Myopathy

Background and Objectives Immune-mediated necrotizing myopathy (IMNM) caused by antibodies against 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) is an inflammatory myopathy that has been epidemiologically correlated with previous statin ...
Paipa, Andrés, Rodríguez-Santiago, Benjamín, Mariscal, Anaís, González-Mera, L., Gallardo, Eduard, de la Calle-Martín, Oscar, Segarra Casas, Alba, Olivé i Plana, Montserrat, Kapetanovic, S., Lleixà, Cinta, Carbayo Viejo, Álvaro, Jou, C., Malfatti, Edoardo, Dobrescu, A., Vesperinas-Castro, Ana, Caballero-Ávila, Marta, Domínguez-González, C., Universitat Autònoma de Barcelona, Querol, Luis, Arteche, A., Llansó, Laura, Nascimento-Osorio, A., Blanco, R., Hernandez-Lain, A.   +23 more
core   +1 more source

Unusual Skin Involvement in Statin-induced Anti-HMGCR Immune-mediated Necrotizing Myopathy

Acta Dermato-Venereologica, 2021
Camille Scard, Corina Bara-Passot, Kévin Chassain, Hervé Maillard   +3 more
doaj   +1 more source