Results 61 to 70 of about 1,968,036 (106)

Maintenance treatment with subcutaneous immunoglobulins in the long-term management of anti-HMCGR myopathy

, 2021
We describe the clinical response to long-term subcutaneous immunoglobulins (SCIg) in anti-3‐hydroxy-3-methyl-glutaryl-coenzyme-A-reductase (anti-HMCGR) myopathy previously treated with intravenous immunoglobulins (IVIg).
Prada V., Quartuccio L., Fiorillo C., Schenone A., Tagliafico A. S., Benedetti L., Manfredi M., Grandis M., Pesce G., Meo G., Gemelli C., De Michelis C., Infantino M., Zuppa A.   +13 more
core   +1 more source

Clinical Characteristics and Evolution of Interstitial Lung Disease in Subtypes of Idiopathic Inflammatory Myositis With Prevalent Lung Manifestation: A Retrospective Analysis

ACR Open Rheumatology, Volume 8, Issue 2, February 2026.
Objective Interstitial lung disease (ILD) is common in idiopathic inflammatory myositis (IIM), particularly in antisynthetase syndrome (ASyS), antimelanoma differentiation‐associated protein 5 (anti‐MDA5) syndrome, and scleromyositis. ILD can progress despite resolution of extrapulmonary symptoms, termed postmyopathic progressive pulmonary fibrosis ...
Julia Clark, Dora Chan, Damon Dhillon, Jan Dutz, Gillian Goobie, Kun Huang   +5 more
wiley   +1 more source

Anti-HMGCR Specificity of HALIP: A Confirmatory Study [PDF]

, 2020
A distinctive new indirect immunofluorescence pattern in liver tissue has been associated with anti-HMGCR autoantibodies. It is known as HALIP (HMGCR Associated Liver Immunofluorescence Pattern).
Baucells, Andrés, Anaís Mariscal, Mariscal, Anaís, Andrés Baucells, Juarez, Candido, Marcelo Alvarado-Cardenas, Maria Angeles Martínez, Alvarado, Marcelo, Martínez, Maria Angeles, Cándido Juárez, Albert Selva-O’Callaghan, Universitat Autònoma de Barcelona, Selva O'Callaghan, Albert, Laura Martinez-Martinez, Martinez-Martinez, Laura   +14 more
core   +1 more source

A Child with Refractory and Relapsing Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Myopathy: Case-Based Review

, 2023
BACKGROUND/OBJECTIVE: Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy is rare in children. Here, we present a boy with relapsing refractory anti-HMGCR myopathy along with a systematic literature review. CASE REPORT: 17-year-old
BATU AKAL, EZGİ DENİZ, ÖZEN, SEZA, AYDINGÖZ, ÜSTÜN, YILDIZ, ADALET ELÇİN, SARI, SEHER, Haliloglu, Goknur, TALİM, BERİL, ŞENER, SEHER, KASAP CÜCEOĞLU, MÜŞERREF   +8 more
core   +1 more source

Case report: Rapid clinical improvement of anti-HMGCR immune-mediated necrotizing myopathy treated with efgartigimod

Frontiers in Immunology
Immune-mediated necrotizing myopathy (IMNM) with anti-HMGCR antibody positivity is characterized by proximal extremity weakness, increased creatine kinase, and extensive muscle edema. There is an urgent need to find more appropriate treatment options for
Quantao Zeng, Kai Chen, Li Zeng, Lixia Xu, Song Tan, Song Tan   +5 more
doaj   +1 more source

MOESM3 of Statin-induced anti-HMGCR myopathy: successful therapeutic strategies for corticosteroid-free remission in 55 patients

, 2020
Additional file 3 : Table S3. Chronology of events leading to corticosteroid-free treatment of patients with anti-HMGCR myopathy (N = 14)
Baptiste Hervier (7069286), Jean-Paul Makhzoum (8272101), Hélène Couture (8272119), Jean-Luc Senécal (84282), Alain Meyer (2383465), Anne-Marie Mansour (8272089), Jessica Nehme (8272098), Ira Targoff (8272122), Marvin Fritzler (3464078), Marie Hudson (289434), Isabelle Deschênes (845781), Farah Zarka (8272104), Sandra Chartrand (8272095), Catherine Isabelle (287264), Yves Troyanov (84281), Jason Karamchandani (4544797), Sandrine Larue (3433376), Jean-Pierre Raynauld (63745), Sara Hussein (105413), Rami Massie (8272116), Geneviève Oligny-Longpré (8272077), Marianne Landry (8272107), Océane Landon-Cardinal (8272080), Jose Ferreira (6338123), Eric Rich (247418), Edith Villeneuve (4282729), Benjamin Ellezam (8272113), Sabrina Hoa (8272083), Josiane Bourré-Tessier (8272086), Vincent Morin (5736995), Jean-Richard Goulet (8272092), Julie Drouin (8272074), Erin O’Ferrall (8272110), Valérie Leclair (3141204)   +33 more
core   +1 more source

Anti-HMG-CoA reductase myopathy, an undesirable evolution of statin induced myopathy: a case report

Journal of Community Hospital Internal Medicine Perspectives, 2019
Statins are commonly used lipid lowering agents which play a pivotal role in reducing cardiovascular morbidity and mortality. Often well tolerated, these HMG-CoA reductase (HMGCR) inhibitors can sometimes cause severe muscle weakness and elevated ...
Sunita Upreti, Beenish Fayyaz, Ramchandran P. Bongu   +2 more
doaj   +1 more source

MOESM5 of Statin-induced anti-HMGCR myopathy: successful therapeutic strategies for corticosteroid-free remission in 55 patients

, 2020
Additional file 5 : Table S5. Chronology of events, from disease onset to maintenance therapy, in patients with anti-HMGCR myopathy presenting with normal strength (N ...
Baptiste Hervier (7069286), Jean-Paul Makhzoum (8272101), Hélène Couture (8272119), Jean-Luc Senécal (84282), Alain Meyer (2383465), Anne-Marie Mansour (8272089), Jessica Nehme (8272098), Ira Targoff (8272122), Marvin Fritzler (3464078), Marie Hudson (289434), Isabelle Deschênes (845781), Farah Zarka (8272104), Sandra Chartrand (8272095), Catherine Isabelle (287264), Yves Troyanov (84281), Jason Karamchandani (4544797), Sandrine Larue (3433376), Jean-Pierre Raynauld (63745), Sara Hussein (105413), Rami Massie (8272116), Geneviève Oligny-Longpré (8272077), Marianne Landry (8272107), Océane Landon-Cardinal (8272080), Jose Ferreira (6338123), Eric Rich (247418), Edith Villeneuve (4282729), Benjamin Ellezam (8272113), Sabrina Hoa (8272083), Josiane Bourré-Tessier (8272086), Vincent Morin (5736995), Jean-Richard Goulet (8272092), Julie Drouin (8272074), Erin O’Ferrall (8272110), Valérie Leclair (3141204)   +33 more
core   +1 more source

An atorvastatin‐induced positive anti‐HMGCR immune‐mediated necrotizing myopathy case

Clinical Case Reports
Key Clinical Message Statins can commonly cause myopathy. Most of the time, stopping the culprit drug should solve the problem. However, if the drug has been discontinued but muscle weakness continues to worsen, immune‐mediated myopathy should be taken ...
Nattanicha Chaisrimaneepan, Jerapas Thongpiya, Pitchaporn Yingchoncharoen, Sakditad Saowapa   +3 more
doaj   +1 more source

Tuberculosis-Induced Immune-Mediated Necrotizing Myopathy: A Challenging Case Scenario in a Non-Endemic Country

Reports
Background and Clinical Significance: Tuberculosis (TB) poses a significant global health challenge; although low–middle income countries carry the heaviest burden, its diagnosis and treatment can be challenging in any country.
Agnese Colpani, Davide Astorri, Andrea De Vito, Giordano Madeddu, Sandro Panese, Nicholas Geremia   +5 more
doaj   +1 more source