Novel targets in headache: A narrative review
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra +5 more
wiley +1 more source
Intrathecal Co-administration of Morphine Facilitated the Anti-nociceptive of Bupivacaine in a Rat Model of Acute Postoperative Pain. [PDF]
Cureus, 2022 Ghosh T, Basu Ray S.
europepmc +1 more source
Anti-inflammatory and anti-nociceptive properties offractionated extracts in different parts of Sambucus ebulus [PDF]
, 2006 Background and purpose: In Iranian folk medicine, the leaves and rhizomes of the plant Sambucus ebulus have been used topically for curing painful joint diseases. This study was undertaken to evaluate the anti-inflammatory and antinociceptive efficacy of
E. Salimi, Pharma +4 more
core
International Journal of Dental Hygiene, EarlyView.ABSTRACT Objective This scoping review aimed to (1) map, analyse, interpret and synthesize data from clinical trials on topical alternatives used to prevent and/or reduce sensitivity caused by in‐office tooth bleaching; and (2) characterize the available evidence on their use for managing sensitivity.
Erik Vinícius Martins Jácome +3 more
wiley +1 more source
Efficacy of 2-Hydroxyflavanone in Rodent Models of Pain and Inflammation: Involvement of Opioidergic and GABAergic Anti-Nociceptive Mechanisms. [PDF]
Molecules, 2022 Khan FA +8 more
europepmc +1 more source
The Expression of Neuropeptides in Pulpitis: A Systematic Review and Meta‐Analysis
International Endodontic Journal, EarlyView.ABSTRACT Background Neuropeptides play key roles in the inflammatory, nociceptive and reparative processes of the dental pulp. Their upregulation has been frequently observed in inflamed pulps, suggesting potential diagnostic value supporting a role for neurogenic inflammation in symptomatic irreversible pulpitis.
N. Watson +3 more
wiley +1 more source
Anti-inflammatory and anti-nociceptive effects of Cinnamon and Clove essential oils nanogels: an in vivo study. [PDF]
BMC Complement Med Ther, 2022 Esmaeili F +5 more
europepmc +1 more source
Scalp Dysesthesia: Emerging Pathophysiologic Insights and Therapeutic Implications
International Journal of Dermatology, EarlyView.Scalp dysesthesia is a chronic condition diagnosed through exclusion. This scoping review synthesized data from 59 patients to identify recurrent clinical features, comorbidities, and management strategies that may support earlier diagnosis. Emerging patterns suggest that neuronal sensitization may underlie common symptoms.
Aditya K. Gupta +4 more
wiley +1 more source
Overview of Anti-Inflammatory and Anti-Nociceptive Effects of Polyphenols to Halt Osteoarthritis: From Preclinical Studies to New Clinical Insights. [PDF]
Int J Mol Sci, 2022 Gambari L +7 more
europepmc +1 more source
Measuring success in HS treatment from the physician's and the patient's perspective
Journal of the European Academy of Dermatology and Venereology, EarlyView.Integrated clinician (HiSCR, IHS4, IHS4‐55, HS‐IGA) and patient (HiSQOL, DLQI) scores, combined with imaging‐based fibrosis and inflammation assessment, redefine treatment success in hidradenitis suppurativa by aligning treat‐to‐target strategies with both inflammatory control and irreversible structural damage.
Georgios Nikolakis +4 more
wiley +1 more source