Results 231 to 240 of about 2,131,769 (283)

Injectable Zn2+‐Alginate Hydrogel Delivering NT3 for Anti‐Inflammatory and Neuroregenerative Therapy in Spinal Cord Injury

Small Structures, Volume 7, Issue 11, November 2026.
An injectable Zn2+‐alginate hydrogel functionalized with His‐tagged NT3 is developed for spinal cord injury repair. The hydrogel modulates microglial polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotype via TNF‐α–NF‐κB pathway inhibition, while sustained NT3 delivery promotes axonal regeneration, synaptogenesis, and remyelination ...
Chao Wang, Quancheng Cheng, Jingyi Yang, Man Li, Yifan Yao, Ziyuan Wang, Xuan Fang, Chunhua Chen, Chuanda Zhu, Weiguang Zhang   +9 more
wiley   +1 more source

Corticosteroid‐augmented interfascial injections for cancer pain management in a dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 9‐year‐old Rottweiler with metastatic osteosarcoma developed severe episodic pain following forelimb amputation and progression of neoplastic disease. Despite extensive multimodal systemic analgesia, including NSAIDs, gabapentin, amantadine and later amitriptyline, the dog showed persistent vocalisation and touch‐evoked pain in the axillary ...
Zita Julianna Szabo, Simona Vincenti, Mariateresa Camerino, Isabelle Iff   +3 more
wiley   +1 more source

Effects of 6‐OHDA‐Mediated Chemical Denervation of Sympathetic Axons in Inguinal Subcutaneous White Adipose Tissue

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10459-10474, November 2026.
ABSTRACT Aims White adipose tissue (WAT) innervation by sensory and sympathetic axons contributes to tissue functions, but the consequences of selectively disrupting sympathetic input to WAT remain incompletely defined. Materials and Methods We utilised 6‐hydroxydopamine (6‐OHDA) as a validated approach to achieve bilateral sympathetic denervation of ...
Gilian Gunsch, Gargi Mishra, Magdalena Blaszkiewicz, Erica de Sousa, Jake W. Willows, Katharine W. Alltop, Annemarie Towle, Shawn Collins, Andre Khalil, Isabel F. Snodgrass, Lara Agha, Kiran Prakash, Rashmika Maganuru, Sugasini Dhavamani, John W. Newman, Kristy L. Townsend   +15 more
wiley   +1 more source

Association of Vitamin B6 and Homocysteine–ACTH Coupling With Depressive and Anxiety Symptoms in Burning Mouth Syndrome: An Exploratory Case–Control Study

Journal of Oral Rehabilitation, Volume 53, Issue 11, Page 2053-2063, November 2026.
In this exploratory case–control study, plasma PLP (vitamin B6), homocysteine and ACTH concentrations did not differ between patients with burning mouth syndrome (BMS) and controls, and none discriminated patients individually. Within patients, however, psychological distress mapped onto a homocysteine–ACTH relationship from which PLP appeared ...
Ashley Lebel, Charlotte Guillouet, André Porporatti, Yves Boucher   +3 more
wiley   +1 more source

Feasibility of Enucleation in Standing Sedated Horses With Retrobulbar Anesthesia and Auriculopalpebral Nerve Block: Impact of Ultrasound Guidance in a Case Series

Veterinary Ophthalmology, Volume 29, Issue 6, November 2026.
ABSTRACT Objective Examining the feasibility of enucleation in standing sedated horses with dorsal retrobulbar anesthesia (RBA) and auriculopalpebral (AP) nerve block and the impact of ultrasound (US) guidance on RBA success. Animals Studied Thirty horses.
Simona Lieberth, Katharina Thieme, Christian Dancker, Roswitha Merle, Johanna Corinna Eule   +4 more
wiley   +1 more source

Risk Factors for Pathologic Fracture in Dogs With Confirmed or Suspected Appendicular Osteosarcoma Treated With Low‐ or Standard‐Dose‐Rate Palliative External Beam Radiation Therapy

Veterinary Radiology &Ultrasound, Volume 67, Issue 6, November 2026.
ABSTRACT Pathologic fracture is a complication of bone cancer with probable increased risk following radiation therapy (RT). Low‐dose‐rate (LDR) RT can spare late‐responding normal tissues by allowing intrafraction DNA repair, which could also impact tumor response. This retrospective cohort study evaluated efficacy and fracture rate in canine patients
Andrew Kurtzman, Elizabeth Rappleyea, Matt Stewart, Jayme Looper, Audrey Billhymer, Kim A. Selting   +5 more
wiley   +1 more source

Persistent Pelvic Adhesions and Fibrotic Remodeling Following Ectopic Lesion Ablation in a Mouse Model of Endometriosis

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
DT‐mediated ablation eliminated detectable donor‐derived ectopic lesions. However, pelvic adhesions, collagen‐rich fibrosis, α‐SMA‐positive fibrotic remodeling, and functional behavioral alterations persisted. These findings indicate that lesion ablation alone is insufficient to resolve established adhesion‐associated fibrotic remodeling and identify ...
Sohyeon Yun, Kyeong A. So, Eunhee M. Jeong, Marissa G. Hoover, Abu Raihan, Lisa Brennaman, Jung‐Yoon Yoo, Andrew M. Kelleher, Tae Hoon Kim, Jung‐Ho Shin, Jae‐Wook Jeong   +10 more
wiley   +1 more source

In Vivo Anti-Nociceptive and Anti-Inflammatory Activities of the Aqueous Extract of the Leaves of Piper sarmentosum [PDF]

Journal of Ethnopharmacology, 2010
Ethnopharmacological relevance: Piper sarmentosum (Piperaceae) is a medicinal plant traditionally used by the Malays to treat headaches, toothaches, coughs, asthma and fever.
Zainul Amiruddin Zakaria, Mohd Roslan Sulaiman, A S Mohamad   +2 more
exaly   +2 more sources

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Anti-Nociceptive and Anti-Inflammatory Activity of Sophocarpine

Journal of Ethnopharmacology, 2009
This study aimed to assess the anti-nociceptive and anti-inflammatory activity of sophocarpine in rodents.The anti-nociceptive effect was evaluated in two experimental animal models and anti-inflammatory effect in three animal models, and sophocarpine was given by tail vein injection for the above study.Pretreatment with a single dose of sophocarpine ...
Bafang Li
exaly   +3 more sources

Monitoring the nociception–anti-nociception balance

Best Practice & Research Clinical Anaesthesiology, 2013
At present, short-acting drugs are used in order to achieve the three components of anaesthesia, that is, analgesia, hypnosis and immobility. Assessment of the 'analgesia' component in daily clinical routine is, in contrast to the other components, still based on very unspecific clinical 'end' points such as movement, tearing, tachycardia or ...
Matthias, Gruenewald, Christoph, Ilies
openaire   +2 more sources