Results 241 to 250 of about 2,131,769 (283)

Toxins in anti-nociception and anti-inflammation

Toxicon, 2004
The use of toxins as novel molecular probes to study the structure-function relationship of ion-channels and receptors as well as potential therapeutics in the treatment of wide variety of diseases is well documented. The high specificity and selectivity of these toxins have attracted a great deal of interest as candidates for drug development.
Wudayagiri, Rajendra, Arunmozhiarasi, Armugam, Kandiah, Jeyaseelan   +2 more
openaire   +2 more sources

Dissociation of rewarding, anti‐aversive and anti‐nociceptive effects of different classes of anti‐nociceptives in the rat

European Journal of Pain, 2011
AbstractIt was previously shown that morphine more potently reduces the affective as compared to the sensory component of nociception, and this effect is independent of morphine's rewarding properties. Here we investigated whether this finding can be generalized to other classes of anti‐nociceptive drugs.
Kris, Rutten, Jean, De Vry, Angela, Robens, Thomas M, Tzschentke, Elizabeth L, van der Kam   +4 more
openaire   +2 more sources

The anti-nociceptive effects of Porphyromonas gingivalis lipopolysaccharide

Archives of Oral Biology, 2019
The objective of this study was to assess the effect of Porphyromonas gingivalis lipopolysaccharide (PG LPS) on acute pain-related behaviour induced in rats and to measure its impact on the levels of pro-inflammatory cytokines (IL-1β, IL-6) and anti-inflammatory (IL-10) cytokines.The Brennan model was used to induce acute pain like signs in rats' hind ...
Junad, Khan, Bollama, Puchimada, Daniel, Kadouri, Tali, Zusman, Fawad, Javed, Eli, Eliav   +5 more
openaire   +2 more sources

Anti-Inflammatory and Anti-Nociceptive Properties of Prunus padus

Journal of Ethnopharmacology, 2012
Prunus padus Linne has been widely used as a traditional medicine, with beneficial effects in numerous diseases, including stroke, neuralgia and hepatitis. In this study, we demonstrated anti-inflammatory and anti-nociceptive activities of the methylene chloride fraction of P.
Dong Seok Cha, Hoon Jeon
exaly   +3 more sources

Anti-Nociceptive and Anti-Inflammatory Potentials of Akebia Saponin D

European Journal of Pharmacology, 2019
Akebia saponin D, which is originates from Dipsacus asper Wall, has been used as a tonic, an analgesic and anti-inflammatory agent for the therapy of low back pain, rheumatic arthritis, traumatic hematoma, habitual abortion and bone fractures in traditional Chinese medicine.
Li-Li Gong, Fei-Fei Han, Lihong Liu
exaly   +3 more sources

Anti-nociceptive effects of oxytocin in rats and mice

Neuroscience Letters, 1994
The existence of neural opioid-mediated networks that are specific for the modulation of nociception is well established. Parallel non-opioid pathways exist, but their underlying physiology is little known. We now report that oxytocin administered intraperitoneally to rats, and intraperitoneally or intracisternally to mice has an anti-nociceptive ...
T, Lundeberg, K, Uvnäs-Moberg, G, Agren, G, Bruzelius   +3 more
openaire   +2 more sources

Flupirtine and antihistamines exert synergistic anti-nociceptive effects in mice

Psychopharmacology, 2023
Drug combinations are commonly used in pain management, which can produce potent analgesic effects with reduced dosage and adverse effects.This study was designed to evaluate the anti-nociceptive effects and adverse effects of new combinations of flupirtine (a Kv7 potassium channel opener) and antihistamines (promethazine, fexofenadine) on acute and ...
Yanming, Chen, Xinyi, Xiao, Chaonan, Huang, Jin, Zhu, Huiling, Zhou, Huimin, Qin, Yu, Bao, Tao, Zhuang, Guisen, Zhang   +8 more
openaire   +2 more sources

Anti-nociceptive and anti-inflammatory properties of Caralluma arabica

Journal of Ethnopharmacology, 2001
In the present study, a 10% ethanolic extract of Caralluma arabica at the doses of 200 and 400 mg/kg was evaluated for the antinociceptive activity using the hot plate and acetic acid induced abdominal constrictions in mice and tail flick method in rats. Oral and topical application of C.
M N, Zakaria, M W, Islam, R, Radhakrishnan, H B, Chen, M, Kamil, A N, Al-Gifri, K, Chan, A, Al-Attas   +7 more
openaire   +2 more sources

Anti-nociceptive Effects of Aconiti Tuber and its Alkaloids

The American Journal of Chinese Medicine, 1994
The anti-nociceptive effect of processed aconiti tuber (TJ-3021), one of the traditional oriental herbal medicines (Kampo), was investigated by utilizing various methods including repeated cold stress and adjuvant articular inflammation in rats and mice.
T, Oyama, T, Isono, Y, Suzuki, Y, Hayakawa   +3 more
openaire   +2 more sources

Chemical Constituents, Anti-Nociceptive and Anti-Inflammatory Activities of Essential Oil of Phyllanthus muellerianus [PDF]

Natural Product Communications, 2019
The aim of the present study was to characterize the chemical composition and to evaluate the anti-inflammatory and an- ti-nociceptive properties of the essential oil from the leaves of Phyllanthus muellerianus (Kuntze) Exell.
Isiaka A Ogunwande, Oladipupo A Lawal, Opeyemi N Avoseh   +2 more
exaly   +2 more sources