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Complement Factor H Mutation-Associated Atypical Haemolytic Uraemic Syndrome Presenting With Dialysis-Dependent Renal Failure: A Case Report. [PDF]

Cureus
Jain A, Mohamed D, Satheesh Nair G, Magriplis M, Yusuf A, Matthews G.   +5 more
europepmc   +1 more source

Interpreting Rituximab Response in Seronegative Membranous Nephropathy [Response to Letter]. [PDF]

Drug Des Devel Ther
Yang Y, Xie X, Xu G.
europepmc   +1 more source

Anti-PLA2R Antibodies as a Prognostic Factor in PLA2R-Related Membranous Nephropathy [PDF]

American Journal of Nephrology, 2015
<b><i>Background:</i></b> The natural course of idiopathic membranous nephropathy (MN) varies, as it is known through favorable outcomes in most patients. However, one third of patients with idiopathic MN will slowly progress to end-stage renal disease (ESRD). To prevent disease progression, patients at high risk to develop ESRD
Sjoerd A M E G Timmermans, Pieter van Paassen   +1 more
exaly   +5 more sources

Containing Anti-PLA2R IgG Antibody Induces Podocyte Injury in Idiopathic Membranous Nephropathy

Renal Failure, 2023
Background: Idiopathic membranous nephropathy is widely recognized as an autoimmune kidney disease that is accompanied by the discovery of several autoantibodies, and the antibody subclass in the circulation of patients with iMN is mainly IgG. However, the direct pathogenic effect of the containing anti-PLA2R IgG antibody on podocytes is not clear ...
Zunsong Wang, Baobao Wang, Lijun Tang
exaly   +5 more sources

The Prognostic Value of Anti-PLA2R Antibodies Levels in Primary Membranous Nephropathy

International Journal of Molecular Sciences, 2023
Anti-PLA2R antibodies (Ab) are a diagnostic and prognostic biomarker in primary membranous nephropathy (PMN). We assessed the relationship between the levels of anti-PLA2R Ab at diagnosis and different variables related to disease activity and prognosis in a western population of PMN patients.
Boris Gilburd, Olga Lesya Kukuy
exaly   +3 more sources

Comparison of Performance and Clinical Utility of Different Methods for Detecting Anti-PLA2R Antibody

Clinica Chimica Acta, 2023
This study aimed to compare the performance of enzyme-linked immunosorbent assay (ELISA) and magnetic particle chemiluminescence immunoassay (MP-CLIA) for detecting anti-phospholipase A2 receptor (PLA2R) antibody and their clinical significance in idiopathic membranous nephropathy (IMN) patients.Serum samples from 448 patients with different types of ...
Zhanzheng Zhao, Jin Shang
exaly   +3 more sources

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Optimal Value for Serum Anti-PLA2R Antibody in Primary Membranous Nephropathy: A Multicenter Observational Study

American Journal of Nephrology, 2022
<b><i>Introduction:</i></b> Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is highly specific for primary membranous nephropathy (PMN). Here, we compare the diagnostic value of different circulating PLA2R-Ab cutoff titers in multicenter cohorts, with particular focus on determining the optimal cutoff value for Chinese ...
Xiaoyan Jia, Minghui Zhao
exaly   +3 more sources