Results 161 to 170 of about 145,320 (184)

Optimal Value for Serum Anti-PLA2R Antibody in Primary Membranous Nephropathy: A Multicenter Observational Study

American Journal of Nephrology, 2022
<b><i>Introduction:</i></b> Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is highly specific for primary membranous nephropathy (PMN). Here, we compare the diagnostic value of different circulating PLA2R-Ab cutoff titers in multicenter cohorts, with particular focus on determining the optimal cutoff value for Chinese ...
Juan Chen, Xiaoyan Jia, Xin Wei, Jiao Li, Yipeng Liu, Ying Lian, Zhao Cui, Minghui Zhao, Sen Luan, Minghui Zhang, Jie Mi, Dongyan Wang, Dongmei Xu   +12 more
openaire   +2 more sources

Quantitative detection of anti-PLA2R antibodies targeting different epitopes and its clinical application in primary membranous nephropathy

Clinical Chemistry and Laboratory Medicine (CCLM), 2022
Abstract Objectives This study aimed to establish time-resolved fluorescence immunoassays to quantitatively detect the autoantibodies targeting different epitopes of M-type phospholipase A2 receptor (PLA2R) and evaluate its clinical application in primary membranous nephropathy (PMN).
Yuan Qin, Qingqing Wu, Huiming Sheng, Ting Li, Xiaobin Liu, Xue Yang, Bo Lin, Xiumei Zhou, Juan Jin, Liang Wang, Biao Huang, Qiang He, Zhigang Hu   +12 more
openaire   +2 more sources

The association of serum anti-PLA2R antibody and glomerular PLA2R antigen staining with clinical manifestations and outcomes in membranous nephropathy

Clinical and Experimental Nephrology, 2023
Phospholipase A2 receptor (PLA2R)-associated membranous nephropathy (MN) was manifested as seropositive for PLA2R antibodies (SAb) and/or glomerular PLA2R antigens' (GAg) deposits. According to the test of SAb and GAg, PLA2R-associated MN can be divided into SAb + /GAg-, SAb-/GAg + , and SAb + /GAg + groups. The clinical characteristics and outcomes of
Shi-Feng, Yang, Xin-Fang, Xie, Wan-Hong, Lu, Ping, Lan, Hui, Liu, Li, Jin   +5 more
openaire   +2 more sources

[Anti-NEP and anti-PLA2R antibodies in membranous nephropathy: an update].

Revue medicale de Bruxelles, 2015
Membranous nephropathy (MN) is the most common cause for nephrotic syndrome in adults and occurs as an idiopathic (primary) or secondary disease. Since the early 2000's, substantial advances have been made in the understanding of the molecular bases of MN. The neutral endopeptidase (NEP) and the receptor for secretory phospholipase A2 (PLA2R) have been
A A, Pozdzik, H, Debiec, , I Brochériou, C, Husson, S, Rorive, N, Broeders, A, Le Moine, P, Ronco, J, Nortier   +8 more
openaire   +1 more source

Comparison of measurements of anti-PLA2R antibodies in Japanese patients with membranous nephropathy using in-house and commercial ELISA

Clinical and Experimental Nephrology, 2019
The prevalence of antibodies against M-type anti-phospholipase A2 receptor (PLA2R) was reported to be ~ 70-80% in early studies on idiopathic membranous nephropathy (iMN) cohorts from Western countries, China, and Korea, and ~ 50% in recent studies on two Japanese iMN cohorts.We developed an in-house enzyme-linked immunosorbent assay (ELISA) for the ...
Hajime, Kaga, Atsushi, Komatsuda, Soh, Yamamoto, Tadashi, Kikuchi, Mika, Kamata, Akiko, Sato, Masafumi, Odaka, Shin-Ichi, Yokota, Naoto, Takahashi, Hideki, Wakui   +9 more
openaire   +2 more sources

Prevalence of Anti-PLA2R Antibodies in Biopsy Proven Membranous Nephropathy in Egyptian Patients

QJM: An International Journal of Medicine
Abstract Background Membranous nephropathy (MN) is among the most common causes of the nephrotic syndrome in nondiabetic adults, accounting for approximately 20 to 30 percent of cases of nephrotic syndrome in White adults.
Magdy Saed El-Sharkawy, Ahmed Abd-Elmoniem Emara, Reem Mohsen El-Sharabasy, Mohamed Mostafa Mostafa Megahed   +3 more
openaire   +1 more source

ANTI-PLA2R ANTIBODY AND PRIMARY MEMBRANOUS NEPHROPATHY: A LITERATURE REVIEW

International Journal of Health Science, 2023
Kívia da Silva Joia, Raphaella Bogado de Bem, Ana Carolina Alves da Conceição, Karina Mourão Costa, Alexandra da Silva Barros, Thaynara Alves de Souza Maciel, Ana Carolina do Amaral Santos de Carvalho Rocha, Raquel Alencar Sampaio Ferraz, Patrick de Abreu Cunha Lopes, Marco Antônio Netto Armando Rangel, Ricardo José de Farias Neto   +10 more
openaire   +1 more source

Serum Anti-PLA2R Antibody Predicts Treatment Outcome in Idiopathic Membranous Nephropathy.

American journal of nephrology, 2017
M-type phospholipase A2 receptor (PLA2R) has been identified as the major target antigen in idiopathic membranous nephropathy (IMN). However, the role of glomerular PLA2R (gPLA2R) and the associations of serum anti-PLA2R antibody (sPLA2R-Ab) titre with diagnosis, treatment and prognosis in IMN need to be further investigated.We screened 148 consecutive
Shi-Yao, Wei, Yu-Xiao, Wang, Jian-Si, Li, Shi-Lei, Zhao, Tian-Tian, Diao, Yu, Wang, Chang, Wang, Ying, Qin, Yang, Cao, Qiuju, Wei, Bing, Li   +10 more
openaire   +1 more source

IgA nephropathy associated with anti-PLA2R antibody positive: a case report

International Urology and Nephrology, 2022
Qian Xiao, Qiu-yue Li
openaire   +1 more source

Anti‐PLA2R antibody in a secondary cause of membranous nephropathy

Nephrology, 2017
M. Hari Krishna Reddy, Anil CV Kumar, B. Sangeetha, R. Ram, V. Siva Kumar   +4 more
openaire   +1 more source