Results 121 to 130 of about 1,082,887 (313)

Antibiotic-Induced Mutagenesis: Under the Microscope

, 2020
Copyright 2020 Revitt-Mills and Robinson. The development of antibiotic resistance poses an increasing threat to global health. Understanding how resistance develops in bacteria is critical for the advancement of new strategies to combat antibiotic ...
Andrew Robinson (19587757), Sarah Revitt-Mills (20237454)   +1 more
core  

A new approach for the discovery of antibiotics by targeting non-multiplying bacteria: a novel topical antibiotic for staphylococcal infections.

, 2010
In a clinical infection, multiplying and non-multiplying bacteria co-exist. Antibiotics kill multiplying bacteria, but they are very inefficient at killing non-multipliers which leads to slow or partial death of the total target population of microbes in
Liu, Y, Alireza Shamaei-Tousi, Coates Anthony, Shamaei-Tousi, A, Hu, Y, Liu Yingjun, Yanmin Hu, Hu Yanmin, Yingjun Liu, Shamaei-Tousi Alireza, Anthony Coates, Coates, A   +11 more
core   +1 more source

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich, Alexis Ogdie, Alisa Stephens Shields, Peter A. Merkel, Shervin Assassi, Elana J. Bernstein, Andreea Bujor, Flavia V. Castelino, Lorinda Chung, Luke B. Evnin, Tracy M. Frech, Jessica K. Gordon, Melissa Griffith, Faye N. Hant, Monica L. Harding, Laura K. Hummers, Dinesh Khanna, Kimberly S. Lakin, Dorota J. Lebiedz‐Odrobina, Yiming Luo, Ashima Makol, Maureen D. Mayes, Zsuzsanna H. McMahan, Jerry Molitor, Duncan F. Moore, Julie Paik, Carrie Richardson, Brian Skaug, Ami A. Shah, Ankoor Shah, Virginia Steen, John M. VanBuren, Elizabeth R. Volkmann, Carleigh Zahn, Nora Sandorfi, for the CONQUER Investigators   +35 more
wiley   +1 more source

A single amino acid substitution in SED-2 β-lactamase leads to increased inhibitor resistance and an extended substrate spectrum

Microbiology Spectrum
β-Lactamases are the leading mechanism of resistance to β-lactam antibiotics in Enterobacterales. Here, we report the detection and characteristics of SED-2, a new member of the Citrobacter sedlakii class A chromosomal β-lactamase SED family.
S. Laviad-Shitrit, H. Kon, D. Bychenko Banyas, R. Efrati Epchtien, M. Bechor, M. Lurie-Weinberger, E. Ben-Zeev, S. Frank, N. Rakovitsky, D. Schwartz, A. Keren-Paz, Y. Carmeli   +11 more
doaj   +1 more source

Are patient views about antibiotics related to clinician perceptions, management and outcome? A multi-country study in outpatients with acute cough

, 2013
Background: outpatients with acute cough who expect, hope for or ask for antibiotics may be more unwell, benefit more from antibiotic treatment, and be more satisfied with care when they are prescribed antibiotics.
Francis, N.K., Hasse Melbye, Butler, Christopher, GRACE Project Group, Little, P, Verheij, Theo J. M., Francis, N., Nick Francis (475899), Verheij, Theo J.M., Samuel Coenen (397250), Paul Little (475903), Butler, C.C., Goossens, Herman, Nuttall, Jacqui, Kelly, M., Mark Kelly, Little, P., Melbye, H., Goossens, H., Samuel Coenen, Hasse Melbye (475905), Melbye, H, Jacqui Nuttall, Kelly, Mark, Melbye, Hasse, Paul Little, Kerenza Hood, Herman Goossens, Mark Kelly (475900), Herman Goossens (305529), Nuttall, J, Nuttal, Jacqui, Butler, Christopher C., Goossens, H, Hood, K., Little, Paul, Coenen, S, Grace Project Group, x, Jacqui Nuttall (475902), Theo J M Verheij, Verheij, T.J., Theo J. M. Verheij (475904), Verheij, TJ, Francis, Nicholas, Coenen, S., Nuttall, J., Francis, Nick, Nick Francis, Hood, K, Coenen, Samuel, Christopher C Butler, Kerenza Hood (475901), Christopher C. Butler (475906), Kelly, M, Verheij, Th.J.M., Francis, N, Kelly, M.J., Hood, Kerenza, Butler, CC   +58 more
core   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

A Bayesian Belief Network to Infer Incentive Mechanisms to Reduce Antibiotic Use in Livestock Production

Efficient policy intervention to reduce antibiotic use in livestock production requires knowledge about the rationale underlying antibiotic usage. Animal health status and management quality are considered the two most important factors that influence ...
Bergevoet, Ron H.M., Ge, Lan, Valeeva, Natasha I., Van Asseldonk, Marcel A.P.M., Hennen, Wil   +4 more
core  

Microbial screening methods for detection of antibiotic residues in slaughter animals

, 2009
Monitoring of food products from animal origin for the presence of antimicrobial residues is preferably done using microbial screening methods because of their high cost-effectiveness.
Pikkemaat, M.G., Mariël G. Pikkemaat
core   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Contribution of Fourier transform infrared spectroscopy for outbreak investigation of carbapenem-resistant Acinetobacter baumannii

Microbiology Spectrum
The value of Fourier transform infrared (FTIR) spectroscopy as an investigation tool for outbreaks caused by Acinetobacter baumannii remains inconclusive. Here, we used FTIR as a real-time tool to investigate a carbapenem-resistant A.
Hadas Kon, Mor N. Lurie-Weinberger, Dafna Chen, Hani Laderman, Elizabeth Temkin, Elena Lomansov, Ibraheem Firan, Worood Aboalhega, Marina Raines, Alona Keren-Paz, Yehuda Carmeli   +10 more
doaj   +1 more source