Results 101 to 110 of about 1,829,235 (358)

Optimizing COVID-19 surveillance in long-term care facilities: a modelling study

BMC Medicine, 2020
Background Long-term care facilities (LTCFs) are vulnerable to outbreaks of coronavirus disease 2019 (COVID-19). Timely epidemiological surveillance is essential for outbreak response, but is complicated by a high proportion of silent (non-symptomatic ...
David R. M. Smith, Audrey Duval, Koen B. Pouwels, Didier Guillemot, Jérôme Fernandes, Bich-Tram Huynh, Laura Temime, Lulla Opatowski, on behalf of the AP-HP/Universities/Inserm COVID-19 research collaboration   +8 more
doaj   +1 more source

Evaluation of the Antibacterial Activity of Chrysomya albiceps Larval Extract and its Synergistic Effects with Antibiotics [PDF]

, 2023
Azza M. Khdre, Tarek G. Ismail, Islam Zakaria, G. ABDEL‐NASSER   +3 more
openalex   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Dietary-based gut flora modulation against Clostridium difficile onset [PDF]

, 2007
Clostridium difficile infection is a frequent complication of antibiotic therapy in hospitalised patients, which today is attracting more attention than ever and has led to its classification as a 'superbug'.
Gibson, G.R., Gougoulias, C., Tuohy, K.M.   +2 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Characterization of Enterobacterales growing on selective CPE screening plates with a focus on non-carbapenemase-producing strains

Microbiology Spectrum
Carbapenem-resistant Enterobacterales (CRE) are divided into two distinct groups: carbapenemase-producing (CPE) and non-carbapenemase-producing (non-CPE).
Reut Efrati Epchtien, Elizabeth Temkin, Mor N. Lurie-Weinberger, Ophir Kastel, Alona Keren-Paz, David Schwartz, Yehuda Carmeli   +6 more
doaj   +1 more source

Antibiotic Prescribing Practices of Filipino Dentists [PDF]

, 2019
There are reports that dentists overprescribe antibiotics which may contribute to antibiotic resistance. This is an exploratory study on antibiotic prescribing practices of Filipino dentists using an online platform to form a basis for antimicrobial ...
Maglutac Jr, Mariano T, Sarmiento, M. A. (Melchor), Yanga-Mabunga, M. S. (Ma)   +2 more
core  

Antibiotic-resistant Escherichia Coli from Retail Poultry Meat with Different Antibiotic Use Claims [PDF]

, 2018
Background We sought to determine if the prevalence of antibiotic-resistant Escherichia coli differed across retail poultry products and among major production categories, including organic, “raised without antibiotics”, and conventional.
Davis, Gregg S., Grande, Heidi, Horwinski, Joseph, Hungate, Bruce A., Koch, Benjamin, Liu, Cindy M., Nordstrom, Lora, Papp, Katerina, Price, Lance B., Waits, Kara, Weaver, Brett   +10 more
core   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Antibiotic susceptibility, heteroresistance, and updated treatment strategies in helicobacter pylori infection [PDF]

, 2017
In this review, we discuss the problem of antibiotic resistance, heteroresistance, the utility of cultures and antibiotic susceptibility tests in Helicobacter pylori (Hp) eradication, as well as the updated treatment strategies for this infection.
De Angelis, Massimiliano, Mascellino, Maria Teresa, Oliva, Alessandra, Porowska, Barbara   +3 more
core   +1 more source