Results 91 to 100 of about 1,197,282 (304)

Antibiotic and Modulation of Microbiota A New Paradigm?

, 2018
Recently new insights on gut microbiota have revolutionized many concepts of the modern medicine. The alteration of microbiota, which is called dysbiosis, has been associated with an expanding list of diseases and conditions.
Antonio Gasbarrini, Gasbarrini, Antonio, Rizzatti, Gianenrico, Gianenrico Rizzatti, Ianiro, Gianluca, Gianluca Ianiro   +5 more
core   +1 more source

A new approach for the discovery of antibiotics by targeting non-multiplying bacteria: a novel topical antibiotic for staphylococcal infections. [PDF]

, 2010
In a clinical infection, multiplying and non-multiplying bacteria co-exist. Antibiotics kill multiplying bacteria, but they are very inefficient at killing non-multipliers which leads to slow or partial death of the total target population of microbes in
Liu, Y, Alireza Shamaei-Tousi, Coates Anthony, Shamaei-Tousi, A, Hu, Y, Liu Yingjun, Yanmin Hu, Hu Yanmin, Yingjun Liu, Shamaei-Tousi Alireza, Anthony Coates, Coates, A   +11 more
core   +2 more sources

Antibiotic-Induced Recruitment of Specific Algae-Associated Microbiome Enhances the Adaptability of Chlorella vulgaris to Antibiotic Stress and Incidence of Antibiotic Resistance

, 2023
Insights into the symbiotic relation between eukaryotic hosts and their microbiome lift the curtain on the crucial roles of microbes in host fitness, behavior, and ecology.
He Wang (250350), He Wang, Jiaqi Ji (13247175), Zaizhao Wang, Ziwei Qin, Xiaoyue Su (16898325), Linjun Zhou, Linjun Zhou (4693858), Jialin Liu (1732168), Jialin Liu, Ziwei Qin (12804381), Kaiqi Li (8753910), Xue Xue (558024), Jiaqi Ji, Xiaoyue Su, Kaiqi Li, Xue Xue, Zaizhao Wang (6108614)   +17 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Genomic and phenotypic characterization of six multidrug-resistant Acinetobacter pittii isolates

Scientific Reports
The Acinetobacter calcoaceticus-baumannii complex is a significant cause of nosocomial infections. While A. baumannii is the most common and clinically significant member globally, recent studies suggest that A.
Nadya Rakovitsky, Mor Lurie-Weinberger, Alona Keren-Paz, Yehuda Carmeli   +3 more
doaj   +1 more source

Optimizing COVID-19 surveillance in long-term care facilities: a modelling study

BMC Medicine, 2020
Background Long-term care facilities (LTCFs) are vulnerable to outbreaks of coronavirus disease 2019 (COVID-19). Timely epidemiological surveillance is essential for outbreak response, but is complicated by a high proportion of silent (non-symptomatic ...
David R. M. Smith, Audrey Duval, Koen B. Pouwels, Didier Guillemot, Jérôme Fernandes, Bich-Tram Huynh, Laura Temime, Lulla Opatowski, on behalf of the AP-HP/Universities/Inserm COVID-19 research collaboration   +8 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Improving antibiotic stewardship skills through interdisciplinary online education: a multicenter teaching intervention for physicians and pharmacists

BMC Medical Education
Background Effective antibiotic prescribing is a core competency for physicians and pharmacists in combating antimicrobial resistance. Despite this, many healthcare professionals report limited confidence in applying antibiotic stewardship principles in ...
Till Koch, Johannes Jochum, Annika van der Linde, Friederike Jahn, Anika Neubert, Evelyn Kramme, Anette Friedrichs   +6 more
doaj   +1 more source

Characterization of Enterobacterales growing on selective CPE screening plates with a focus on non-carbapenemase-producing strains

Microbiology Spectrum
Carbapenem-resistant Enterobacterales (CRE) are divided into two distinct groups: carbapenemase-producing (CPE) and non-carbapenemase-producing (non-CPE).
Reut Efrati Epchtien, Elizabeth Temkin, Mor N. Lurie-Weinberger, Ophir Kastel, Alona Keren-Paz, David Schwartz, Yehuda Carmeli   +6 more
doaj   +1 more source

Comparison of antibiotic consumption in the three internal medicine departments

, 2014
Because of the excessive usage of antibiotics, development of resistant bacteria emerges and therefore monitoring of antibiotic resistance and consumption is essential.
Kristínardóttir, Ester
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