Results 1 to 10 of about 842,782 (192)

BashTheBug: a crowd of volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates

bioRxiv, 2021
Tuberculosis is a respiratory disease that is treatable with antibiotics. An increasing prevalence of resistance means that to ensure a good treatment outcome it is desirable to test the susceptibility of each infection to different antibiotics ...
P. Fowler, Carla Wright, Helen Spiers, Tingting Zhu, E. Baeten, Sarah W Hoosdally, Ana Lu´ıza, Gibertoni Cruz, A. Roohi, S. Kouchaki, T. Walker, T. Peto, Grant Miller, C. Lintott, D. Clifton, D. Crook, A. Walker   +16 more
semanticscholar   +1 more source

Fever work-up unfolds a rare diagnosis of native valve endocarditis caused by Mycobacterium abscessus

Indian Journal of Pathology and Microbiology, 2019
Endocarditis caused by Mycobacterium abscessus is rare and often missed without appropriate blood cultures. It does not respond to standard antitubercular treatment and is also resistant to many other antibiotics.
Anita Sharma, Irneet Mundi, Karun Behal, Navreet Kaur, Pooja Singh, Manish Mahant   +5 more
doaj   +1 more source

Synthesis, antitubercular activity and mechanism of resistance of highly effective thiacetazone analogues [PDF]

, 2013
Defining the pharmacological target(s) of currently used drugs and developing new analogues with greater potency are both important aspects of the search for agents that are effective against drug-sensitive and drug-resistant Mycobacterium tuberculosis ...
A Alahari, A Alahari, A Banerjee, A Bhatt, AE Grzegorzewicz, AK Ojha, AR Baulard, C Vilcheze, CK Stover, D Fegan, D Fegan, Derek Craig, E Dubnau, E Sacco, Emilie Vialla, F Wang, FM Shahab, G Lutfalla, Geoffrey D. Coxon, JA Caminero, Jean Louis Herrmann, JM Belardinelli, JR Wei, K Takayama, L Kremer, Laila Gannoun-Zaki, Laurent Kremer, LE Bermudez, LG Dover, LS Kremer, MA Espinal, MS Glickman, N Slama, P Nunn, PT Davidson, R Mondal, R Veyron-Churlet, R Veyron-Churlet, RM Corrales, Rosa Milagros Corrales, S Cantaloube, TD Bugg, V Rao, VK Sambandamurthy, Y Rombouts   +44 more
core   +9 more sources

Dual antibiotherapy of tuberculosis mediated by inhalable locust bean gum microparticles [PDF]

, 2017
Despite the existence of effective oral therapy, tuberculosis remains a deadly pathology, namely because of bacterial resistance and incompliance with treatments.
Alves, Ana D., Buttini, Francesca, Cavaco, Joana S., Grenha, Ana, Guerreiro, Filipa, Pontes, Jorge Filipe, Rodrigues, Susana, Rosa Da Costa, Ana   +7 more
core   +1 more source

Empirical Treatment of Highly Suspected Nontuberculous Mycobacteria Infections Following Aesthetic Procedures

Archives of Plastic Surgery, 2014
Background Infection caused by nontuberculous mycobacteria (NTM) has been increasing. Awareness of this infection is crucial yet problematic. Delayed management may lead to destructive results.
Hyung Rok Kim, Eul Sik Yoon, Deok Woo Kim, Na Hyun Hwang, Yoo Seok Shon, Byung Il Lee, Seung-Ha Park   +6 more
doaj   +1 more source

Isoniazid Induced Toxic Epidermal Necrolysis in a HIV Positive Patient during Treatment for Extra Pulmonary Tuberculosis: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2019
Toxic Epidermal Necrolysis (TEN) is characterised by extensive erythema, necrosis, and bullous detachment of the epidermis and mucous membranes.
Bhanukumar Muthaiah, George Mathew Panachiyil, Tirin Babu, Allu Harshavardhini   +3 more
doaj   +1 more source

Erythema induratum of bazin – Skin lesions with pyrexia of unknown origin undiagnosed for 4 years

International Journal of Mycobacteriology, 2022
Erythema induratum of Bazin is characterized by chronic, tender, erythematous, indurated subcutaneous nodules on the lower extremities caused by tuberculin hypersensitivity.
Mansoor C Abdulla
doaj   +1 more source

In vitro assessment of antimicrobial, antioxidant, and cytotoxic properties of Saccharin-Tetrazolyl and-Thiadiazolyl derivatives: the simple dependence of the pH value on antimicrobial activity [PDF]

, 2019
The antimicrobial, antioxidant, and cytotoxic activities of a series of saccharin-tetrazolyl and -thiadiazolyl analogs were examined. The assessment of the antimicrobial properties of the referred-to molecules was completed through an evaluation of ...
Andrade, Joana M., Cabral, Lília, Cristiano, Maria de Lurdes, Frija, Luís M. T., Ntungwe, Epole, Pombeiro, Armando J. L., Rijo, Patrícia, Sitarek, Przemysław, Toma, Monika, Śliwiński, Tomasz   +9 more
core   +1 more source

Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay [PDF]

, 2013
Objectives: Lead antituberculosis (anti-TB) molecules with novel mechanisms of action are urgently required to fuel the anti-TB drug discovery pipeline.
Bhakta, Sanjib, Birchall, K., Evangelopoulos, Dimitrios, Gibbons, S., Gupta, Antima, Guzman, Juan D., Malkinson, J., McHugh, T.D., Mwaigwisya, S., Saxty, B.   +9 more
core   +1 more source

Nanoparticle-Formulated Curcumin Prevents Posttherapeutic Disease Reactivation and Reinfection with Mycobacterium tuberculosis following Isoniazid Therapy

Frontiers in Immunology, 2017
Curcumin, the bioactive component of turmeric also known as “Indian Yellow Gold,” exhibits therapeutic efficacy against several chronic inflammatory and infectious diseases.
Sultan Tousif, Sultan Tousif, Dhiraj Kumar Singh, Dhiraj Kumar Singh, Sitabja Mukherjee, Shaheer Ahmad, Rakesh Arya, Ranjan Nanda, Anand Ranganathan, Maitree Bhattacharyya, Luc Van Kaer, Santosh K. Kar, Gobardhan Das   +12 more
doaj   +1 more source