Results 41 to 50 of about 951,869 (260)
Molecules, 2022 Natural and synthetic β-lactam derivatives constitute an interesting class of compounds due to their diverse biological activity. Mostly used as antibiotics, they were also found to have antitubercular, anticancer and antidiabetic activities, among ...
Faïza Diaba +2 more
doaj +1 more source
Tubercular round pneumonia simulating a mass lesion in an adult
The Egyptian Journal of Internal Medicine, 2018 Round pneumonia, a benign cause of spherical lesions seen on chest imaging, can many a times be difficult to distinguish from bronchogenic carcinomas. Although relatively less common in adults, this entity is seen in most pulmonary medicine and radiology
Ved Prakash +5 more
doaj +1 more source
Synthesis of 2-oxo-azetidine derivatives of 2-amino thiazole and their biological activity [PDF]
, 2012 A new series of N-[2-(2-aminothiazolyl)ethyl]-4-(substitutedphenyl)- 3-chloro-2-oxo-1-iminoazetidine, compounds 4(a-m) have been synthesized from 2-aminothiazole as a starting material.
Samadhiya Pushkal +3 more
core +1 more source
Drug delivery systems for potential treatment of intracellular bacterial infections. [PDF]
, 2010 Despite the advent of a considerable number of new antibiotics, treatment of intracellular pathogens still represents a major pharmaceutical challenge.
Ariza, J. (J.) +3 more
core +1 more source
bioRxiv, 2021 Tuberculosis is a respiratory disease that is treatable with antibiotics. An increasing prevalence of resistance means that to ensure a good treatment outcome it is desirable to test the susceptibility of each infection to different antibiotics ...
P. Fowler +16 more
semanticscholar +1 more source
Jornal Brasileiro de Pneumologia, 2012 A correlação entre a resistência à pirazinamida (PZA) e a resistência a outros fármacos antituberculose de primeira linha foi investigada em 395 cepas de Mycobacterium tuberculosis provenientes de espécimes clínicos, que representavam 14% do total de ...
Leila de Souza Fonseca +5 more
doaj +1 more source
A favourable solubility of isoniazid, an antitubercular antibiotic drug, in alternative solvents [PDF]
Fluid Phase Equilibria, 2012 Abstract The sufficient solubility of isoniazid in alternative solvents obtained in this work can open new perspectives in pharmaceutical processing. Solid–liquid equilibrium (SLE) measurements have been made using a dynamic (synthetic) method.
Andreia Forte +3 more
openaire +1 more source
Clinically Relevant Interactions between Atypical Antipsychotics and Anti-Infective Agents
Pharmaceuticals, 2020 This is a comprehensive review of the literature on drug interactions (DIs) between atypical antipsychotics and anti-infective agents that focuses on those DIs with the potential to be clinically relevant and classifies them as pharmacokinetic (PK) or ...
Edoardo Spina +3 more
doaj +1 more source
Machine Learning Prediction of Mycobacterial Cell Wall Permeability of Drugs and Drug-like Compounds
Molecules, 2023 The cell wall of Mycobacterium tuberculosis and related organisms has a very complex and unusual organization that makes it much less permeable to nutrients and antibiotics, leading to the low activity of many potential antimycobacterial drugs against ...
Eugene V. Radchenko +3 more
doaj +1 more source
Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea [PDF]
, 2016 Tuberculosis is a major threat for mankind and the emergence of resistance strain of Mycobacterium tuberculosis (Mtb) against first line antibiotics makes it lethal for human civilization.
Charan Raja, Mamilla R. +10 more
core +1 more source