Results 111 to 120 of about 60,579 (143)
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Human Monoclonal Antibodies: Recent Achievements
Hospital Practice, 1994The latest developments include an anti-HIV antibody that has 1,000 times the affinity of natural antibody and that neutralizes primary clinical isolates, and an anti-RSV antibody that reduces viral titers in mice by 12,000-fold within 24 hours.
D R, Burton, C F, Barbas
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Monoclonal antibodies to human amnion
Journal of Reproductive Immunology, 1986Mouse hybridoma cell lines secreting monoclonal antibodies to human amnion were established. The reactivities of eight of these monoclonal antibodies (GB1, GB3, GB4, GB5, GB6, GB9, GB10 and GB11) on human skin and term extra-embryonic tissues, which included reflected amniochorions, basal plates, placentae, chorionic plates and umbilical cords, are ...
B L, Hsi, C J, Yeh
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1985
The monoclonal antibody technology has had a major impact on the serological and biochemical analysis of human tumor antigens. Monoclonal antibodies have rapidly led to the identification and characterization of a large number of antigenic determinants on cancer cells.
Alan N. Houghton, Richard J. Cote
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The monoclonal antibody technology has had a major impact on the serological and biochemical analysis of human tumor antigens. Monoclonal antibodies have rapidly led to the identification and characterization of a large number of antigenic determinants on cancer cells.
Alan N. Houghton, Richard J. Cote
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Monoclonal Antibody to Human Cytotrophoblast
American Journal of Reproductive Immunology, 1984ABSTRACT: A monoclonal antibody (18B/A5) has been generated against human first trimester trophoblast membranes which, unlike others so far reported in the literature, reacted only with cytotrophoblast and not with syncytiotrophoblast. Although the identity of the target antigen has not yet been established, the antibody could be a valuable tool for ...
Y W, Loke, S, Day
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Monoclonal antibodies against human prostasomes
The Prostate, 1998The prostasomes are secreted into the gland ducts of the human prostate. At ejaculation, these native prostasomes are expelled with the secretions of the prostate and appear in the seminal plasma as seminal prostasomes, where they facilitate sperm function in various ways.
B O, Nilsson +4 more
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Monoclonal Antibody to Human Thyrotropin*
The Journal of Clinical Endocrinology & Metabolism, 1982Using the technique of somatic cell fusion, a monoclonal antibody to human TSH (hTSH) has been produced. The monoclonal antibody (anti-hTSH 1/1) has an affinity (Kd = 4.04 x 10(-9) M/liter) for hTSH which is slightly less than that of the polyclonal antisera (Kd = 9.8 x 10(-10) M/liter) derived from the same mouse used for the fusion experiment.
Ridgway, E C +3 more
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Human and chimpanzee monoclonal antibodies
Journal of Immunological Methods, 1985Monoclonal antibody-secreting cell lines were isolated after transformation of peripheral blood leukocytes with Epstein-Barr virus. Blood samples were obtained from human donors having circulating antibodies against hepatitis viruses (HAB, HBV), rubella, or rabies virus and from a chimpanzee infected with HAV. Dextran-isolated leukocytes were submitted
F C, Van Meel +2 more
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Monoclonal Antibodies Against Human Haptoglobin
Hybridoma, 1989Three monoclonal antibodies: 2.36.71.41, 7.60.66.55, and 18.4.40. 80 to human haptoglobin 2-1 were produced, purified and characterized. The affinity constants ranged within 0.3-2.4 x 10(8) M-1. The monoclonal antibodies 7.60.66.55 and 18.4.40.80 reacted with beta subunit of haptoglobin, showed similar epitope affinities and epitope densities on main ...
I, Katnik +4 more
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Monoclonal antibodies against human chondrocytes
In Vitro Cellular & Developmental Biology - Animal, 1996Cell-specific antigens are mainly found in cells or membrane surfaces rather than in the surrounding matrix. However, until now it was not possible to produce antibodies specific for cellular structures of chondrocytes. In 1989, Lance (Immunol. Lett.
Bujia, J. +6 more
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Monoclonal Antibodies to Human Nephrin
Hybridoma and Hybridomics, 2004Nephrin is a 180-200-kDa transmembrane protein of the immunoglobulin superfamily. In the kidney, nephrin localizes to the slit diaphragm (SD) between interdigitating podocyte foot processes and mutations in the nephrin gene cause congenital nephrotic syndrome.
Vesa, Ruotsalainen +4 more
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