Results 241 to 250 of about 5,065,448 (337)

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

Trigeminal involvement in dermatomyositis with double positivity for anti-transcriptional intermediary factor 1 gamma and anti-Ku antibodies: A case report and literature review. [PDF]

J Int Med Res
Yingchao S, Cheng X, Mingli O, Ning S, Xiayan X, Yongmei H.   +5 more
europepmc   +1 more source

Screening plateletpheresis donors for HLA antibodies on two high‐throughput platforms and correlation with recipient outcome

, 2010
Karen Quillen, Consuelito Medrano, Sharon Adams, Brett S. Peterson, Julia Hackett, Susan F. Leitman, Harvey G. Klein, David F. Stroncek   +7 more
openalex   +2 more sources

Subtyping Influenza A Virus with Monoclonal Antibodies and an Indirect Immunofluorescence Assay [PDF]

, 2011
Jennifer G. Johnson, Angela D. Higgins, Adriana Navarro, Yung T. Huang, Frank L. Esper, Nicole Barton, Derek Esch, Carl J. Shaw, Paul D. Olivo, Lynn Yihong Miao   +9 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Modular generation of multispecific antibodies using protein trans-splicing. [PDF]

MAbs
Shadish JA, Bagert JD, Lee AN, Sharp KK, Yang C, Li Y, Wang R, Shin S, Malik AA, Lin J, Huang F, Liu W, Mazor Y.   +12 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Evaluation of multiplexed liquid glycan Array (LiGA) for serological detection of glycan-binding antibodies. [PDF]

Glycobiology
Reddy R, Carpenter E, Halpin A, Sojitra M, Peng C, Lima GM, Xue X, Yan K, Pearcy J, Ellis M, Motyka B, Lowary TL, West L, Derda R.   +13 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Targeting Myeloid Cells for Cancer Immunotherapy. [PDF]

Cancer Immunol Res
Blanchard L, Mijacika A, Osorio JC.
europepmc   +1 more source