Results 261 to 270 of about 3,695,210 (335)

Antibodies Against SARS-CoV-2 Nucleocapsid Protein Possess Autoimmune Properties. [PDF]

Antibodies (Basel)
Rak A, Zabrodskaya Y, Wong PF, Isakova-Sivak I.   +3 more
europepmc   +1 more source

Pharmacological Properties of Traditional Medicine (XXX): Effects of Gyokuheifusan on Murine Antigen-Specific Antibody Production

, 2005
Toshiaki Makino, Shinya Sasaki, Yoshiaki Ito, Yoshihiro Kano   +3 more
openalex   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Development of an anti‐BAG3 humanized antibody for treatment of pancreatic cancer

, 2019
Anna Basile, Margot De Marco, Michelina Festa, Antonia Falco, Vittoria Iorio, Luana Guerriero, Daniela Eletto, Domenica Rea, Claudio Arra, Alessia Lamolinara, Patrizia Ballerini, Verena Damiani, Alessandra Rosati, Gianluca Sala, Maria Caterina Turco, Liberato Marzullo, Vincenzo De Laurenzi   +16 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A novel TM4SF4-targeting therapeutic antibody candidate with antitumor activity by blocking IGF1R and CD44 signaling and downregulating PD-L1 and B7-H4. [PDF]

Theranostics
Kim RK, Heo CK, Choi MJ, Kahm YJ, Kim MK, Lee M, Lee JY, Park H, Jung U, Shin BC, Kim BJ, Kim SC, Cho EW, Ryu CJ, Kim IG.   +14 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Targeting the epidermal growth factor receptor using IgM antibodies: toward next generation cancer immunotherapy. [PDF]

Front Immunol
Somboon K, Bond PJ, Samsudin F.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Therapeutic Antibodies in Hematology: Advances in Malignant and Non-Malignant Disorders. [PDF]

Cells
Yasui H, Idogawa M, Ishida T, Imai K.
europepmc   +1 more source