Results 261 to 270 of about 5,065,448 (337)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Large-scale profiling of antibody reactivity to glycolipids in patients with Guillain-Barré syndrome. [PDF]

Brain
Thomma RCM, Halstead SK, de Koning LC, Wiegers EJA, Gourlay DS, Tio-Gillen AP, van Rijs W, Andersen H, Antonini G, Arends S, Attarian S, Barroso FA, Bateman KJ, Benedetti L, Van den Bergh P, Bürmann J, Busby M, Casasnovas C, Dardiotis E, Davidson A, Feasby TE, Fehmi J, Galassi G, Garcia-Sobrino T, Granit V, Gutiérrez-Gutiérrez G, Hadden RDM, Harbo T, Hartung HP, Hasan I, Holt JKL, Islam Z, Karafiath S, Katzberg HD, Kolb N, Kusunoki S, Kuwabara S, Kuwahara M, Lehmann HC, Leonhard SE, Martín-Aguilar L, Monges S, Nobile-Orazio E, Pardo J, Pereon Y, Querol L, Reisin RC, Rinaldi S, Ripellino P, Roberts RC, Scheidegger O, Shahrizaila N, Sheikh KA, Silvestri NJ, Sindrup SH, Stein B, Tan CY, Tankisi H, Visser LH, Waheed W, Huizinga R, Jacobs BC, Willison HJ, IGOS consortium .   +63 more
europepmc   +1 more source

IgE versus IgG and IgA: Differential roles of allergen‐specific antibodies in sensitization, tolerization, and treatment of allergies

Edward F. Knol, R. J. Joost van Neerven
openalex   +1 more source

People living with HIV display increased anti-apolipoprotein A1 auto-antibodies, inflammation, and kynurenine metabolites: a case–control study [PDF]

Miguel A. Frias, Sabrina Pagano, Nasim Bararpour, Jonathan Sidibé, Festus Kamau, Vanessa Fétaud-Lapierre, Peter Hudson, Aurélien Thomas, Sandrine Lecour, Hans Strijdom, Nicolas Vuilleumier   +10 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

The Yin and Yang of Antibodies in Viral Infectious Diseases. [PDF]

Diseases
He J, Kam YW, Lum FM.
europepmc   +1 more source

Development and application of a colloidal-gold immunochromatographic strip for detecting Getah virus antibodies [PDF]

Zhiwen Jiang, Ying Qin, Letian Zhang, Gang Xing, Zhiyu Shi, Wanjie Song, Georgi M. Dobrikov, Jie Chen, Shuo Su   +8 more
openalex   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Different antibody isotypes against tuberculosis: what we know and what we need to know. [PDF]

Front Immunol
Li H, Li H.
europepmc   +1 more source