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Case Report: A severe drug-induced immune hemolytic anemia caused by vancomycin. [PDF]
Xie Y +7 more
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Association between anti-Mullerian hormone and antithyroid antibodies detectability and positivity in women assisted at a fertility clinic. [PDF]
Oliveira YIL +4 more
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A validated panel of commercial antibodies for reliable detection of FET proteins
Tacconelli S +8 more
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Computational Analysis of Antibody Paratopes for Antibody Sequences in Antibody Libraries
2022To ensure the functionalities of the antibodies in phage-displayed synthetic antibody libraries, we use computational method to evaluate the designs of the antibody libraries. The computational methodologies developed in our lab for designing antibody library provide rich information on the function of the designed antibody sequences-adequate antibody ...
Hung-Pin, Peng, An-Suei, Yang
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Antibody and antibody fragments for cancer immunotherapy
Journal of Controlled Release, 2020Antibody has become the most rapidly expanding class of pharmaceuticals for treating a wide variety of human diseases including cancers. Especially, with the fast development of cancer immunotherapy, antibody drugs have become the most promising therapeutic for curing cancers.
Weizhi Chen, Yang Yuan, Xiqun Jiang
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Current Opinion in Chemical Biology, 1998
Following the end of the first decade in catalytic antibody research, recent efforts are reflecting a more introspective view of the field. Notably, X-ray crystal structure analyses of antibody catalysts are permitting an increased understanding of the evolution and modus operandi of these remarkable biocatalysts. Additionally, the breadth and scope of
P, Wentworth, K D, Janda
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Following the end of the first decade in catalytic antibody research, recent efforts are reflecting a more introspective view of the field. Notably, X-ray crystal structure analyses of antibody catalysts are permitting an increased understanding of the evolution and modus operandi of these remarkable biocatalysts. Additionally, the breadth and scope of
P, Wentworth, K D, Janda
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Antibodies and Selection of Monoclonal Antibodies
2015Monoclonal antibodies are universal binding molecules with a high specificity for their target and are indispensable tools in research, diagnostics and therapy. The biotechnological generation of monoclonal antibodies was enabled by the hybridoma technology published in 1975 by Köhler and Milstein.
Katja, Hanack +2 more
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Phage antibodies: will new ‘coliclonal’ antibodies replace monoclonal antibodies?
Trends in Biotechnology, 1992Antibodies can now be rapidly isolated from large and diverse recombinant libraries by displaying functional antibody fragments on the surface of bacteriophage particles and directly selecting with antigen. This method has been used to isolate antibodies, including human antibodies, with and without immunization, and to improve the affinity and ...
D J, Chiswell, J, McCafferty
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Monoclonal Antibodies, Bispecific Antibodies and Antibody-Drug Conjugates in Oncohematology
Recent Patents on Anti-Cancer Drug Discovery, 2020Background: The therapeutic outcomes and the prognosis of patients with various hematologic malignancies are not always ideal with the current standard of care. Objective: The aim of this study is to analyze the results of the use of monoclonal antibodies, bispecific antibodies and antibody-drug conjugates for the therapy of malignant hemopathies.
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