Results 201 to 210 of about 174,708 (252)
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Antibody-dependent cellular cytotoxicity in asthmatics
Journal of Allergy and Clinical Immunology, 1977Using a 51Cr-labeled, antibody-coated chicken red blood cell assay system, mononuclear cell and granulocyte preparations from infectious asthmatics, noinfectious asthmatics, and normal controls were tested for antibody-dependent cellular cytotoxicity (ADCC) capacity.
D K, Flaherty +5 more
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Antibody-dependent cellular cytotoxicity in poikilotherms
Developmental & Comparative Immunology, 197751Cr-chromate labelled chicken red blood cells, treated with rabbit (anti-chicken red blood cell) serum, are lysed in vitro, in the absence of complement, by spleen cells from Xenopus laevis, Ambystoma mexicanum or Lacerta viridis. Optimal conditions for lysis by Xenopus spleen cells were determined.
R D, Jurd, A, Doritis
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The role of apoptosis in antibody-dependent cellular cytotoxicity
Cancer Immunology Immunotherapy, 1993Apoptosis in three lymphoma cell lines has been studied following cytotoxicity induced in vitro by normal human blood lymphocytes utilizing either natural killer (NK) or antibody-dependent cellular cytotoxic (ADCC) mechanisms. Guinea-pig L2C leukaemic lymphocytes, but not the human cell lines Daudi and Jurkat, revealed a degree of time- and temperature-
S J, Curnow +2 more
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Antibody-dependent cellular cytotoxicity and influenza virus
Current Opinion in Virology, 2017Antibodies are a key defence against influenza infection and disease, but neutralizing antibodies are often strain-specific and of limited utility against divergent or pandemic viruses. There is now considerable evidence that influenza-specific antibodies with Fc-mediated effector functions, such as antibody-dependent cellular cytotoxicity (ADCC), can ...
Vanderven, Hillary A. +3 more
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Antibody‐dependent cellular cytotoxicity in HIV infections
The FASEB Journal, 1996ADCC is an important immune effector mechanism against tumor and virus‐infected cells that can be destroyed by the combined action of specific antibodies of IgG isotype against cell surface‐associated antigens and effector cells, predominantly of the NK phenotype. ADCC has been shown to function in vivo in several systems.
A, Ahmad, J, Menezes
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Polymorphonuclear Leukocytes in Antibody-Dependent Cellular Cytotoxicity
The Journal of Immunology, 1975Abstract Human polymorphonuclear leukocytes (PMN) lyse antibody-coated target cells in an immunologically specific fashion—antibody-dependent cellular cytotoxicity (ADCC). PMN-mediated cytolysis is independent of complement, de novo protein synthesis, and DNA replication.
R P, Gale, J, Zighelboim
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Monocyte antibody-dependent cellular cytotoxicity in cancer patients
Cancer Immunology, Immunotherapy, 1984Antibody-dependent cellular cytotoxicity (ADCC) mediated by peripheral blood monocytes was determined in 120 patients who had gastrointestinal tract (GIT), lung and breast cancer, melanoma, or Hodgkin's and non-Hodgkin's lymphoma. Results were expressed in terms of maximum cytotoxicity and cytotoxicity at E:T = 1:10 and were compared with the results ...
N J, De Young, P G, Gill
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Antibody-Dependent Cellular Cytotoxicity in Some Lymphoreticular Diseases
Tumori Journal, 1984Antibody-dependent cellular cytotoxicity mediated by K cells against chicken erythrocytes was measured in 113 patients with malignant lymphoreticular disorders and compared with 230 controls. The results were expressed as the specific cytotoxicity of a fixed number of cells and also by cytotoxic capacity, which measures the number of cytolytic units in
J C, Voltarelli +2 more
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Melatonin‐induced enhancement of antibody‐dependent cellular cytotoxicity
Journal of Pineal Research, 1991Abstract: Antibody‐dependent cellular cytotoxicity (ADCC) is a lytic mechanism in which a specific antibody acts cooperatively with leukocytic effector cells to induce target cell lysis. In this paper, the effect of exogenous melatonin on ADCC was examined. It was found that two evening intravenous injections of melatonin (1 mg/kg b.w.) was sufficient
M, Giordano, M S, Palermo
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Antibody-dependent cellular cytotoxicity in bullous diseases
Journal of the American Academy of Dermatology, 1982Antibody-dependent cellular cytotoxicity (ADCC) was studied in six patients with pemphigus vulgaris, six patients with bullous pemphigoid, and thirteen controls. All patients had extensive, severe disease. The target cell used was a human lymphoblastoid cell line (LA 237) coated with either heterologous (rabbit R3) or homologous (anti-HLA-A5) antiserum.
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