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A Quantitative Relationship Between Antibody Affinity and Antibody Avidity

Immunological Investigations, 1987
The relationship between antibody avidity, measured by the dissociation of the antigen-antibody bond in antigen excess, and antibody affinity was studied. Complexes of radiolabelled antigen and antibody of known affinity were prepared in vitro and allowed to stand for seven days to reach equilibrium.
openaire   +2 more sources

Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies

Ca-A Cancer Journal for Clinicians, 2022
Paolo Tarantino   +2 more
exaly  

Avidity in antibody effector functions and biotherapeutic drug design

Nature Reviews Drug Discovery, 2022
Simone C Oostindie, Janine Schuurman
exaly  

Multivalence and Affinity of Antibody

International Archives of Allergy and Immunology, 1973
F, Karush, C L, Hornick
openaire   +2 more sources

Reducing affinity as a strategy to boost immunomodulatory antibody agonism

Nature, 2023
Christian M Orr   +2 more
exaly  

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