Results 31 to 40 of about 181,569 (191)

ANTIDIABETIC ACTIVITY TEST USING AMLA FRUIT (PHYLLANTHUS EMBLICA L) EXTRACT IN ALLOXAN-INDUCED BALB/C MICE

Journal of Vocational Health Studies, 2019
Background: The content of secondary metabolites in amla (phyllanthus emblica L.) such as flavonoids and phenols have the potential as an antioxidant.
Putu Lakustini Cahyaningrum, Sang Ayu Made Yuliari, Ida Bagus Putra Suta   +2 more
doaj   +1 more source

Antidiabetic Bioactivity of Ethyl Acetate Extract of Fungus Comb

Indonesian Journal of Chemical Analysis
The ethyl acetate extract of fungus comb was investigated for its potential as an α-glucosidase enzyme inhibition agent. The extract was evaluated using bioassay methods to determine its IC50 values against enzyme activity, alongside phytochemical ...
Raja David Virgilius, Irmanida Batubara
doaj   +1 more source

Meta‐analysis of the association between sodium‐glucose co‐transporter‐2 inhibitors and risk of skin cancer among patients with type 2 diabetes [PDF]

, 2018
A slight increase in melanoma risk was observed among sodium‐glucose co‐transporter‐2 (SGLT‐2) inhibitor users in the regular reports. However, the association remains uncertain.
Bailey, Barnett, Bode, Brockhaus, Cefalu, Chen, Deeks, DeFronzo, Ferrannini, Fralick, Grunberger, Haring, Higgins, Higgins, Häring, Jabbour, Kashiwagi, Kohler, Kovacs, Leiter, Lewin, Li, Nauck, Neal, Ridderstrale, Roden, Søfteland, Wanner, Yang, Zaccardi, Zinman   +30 more
core   +1 more source

Activation of AMP-activated protein kinase by metformin induces protein acetylation in prostate and ovarian cancer cells [PDF]

, 2016
AMP-activated protein kinase (AMPK) is an energy sensor and master regulator of metabolism. AMPK functions as a fuel gauge monitoring systemic and cellular energy status.
Galdieri, Luciano, Gatla, Himavanth, Vancura, Ales, Vancurova, Ivana   +3 more
core   +2 more sources

Liposome Encapsulation Enhances the Antidiabetic Efficacy of Silibinin

Pharmaceutics
Silibinin has considerable therapeutic potential for the treatment of diabetes through anti-inflammatory, antioxidant, and immunomodulatory properties. However, the therapeutic application of silibinin is quite limited due to its poor bioavailability. In
Svetlana Dinić, Jelena Arambašić Jovanović, Aleksandra Uskoković, Aleksandra Jovanović, Nevena Grdović, Jovana Rajić, Marija Đorđević, Ana Sarić, Branko Bugarski, Melita Vidaković, Mirjana Mihailović   +10 more
doaj   +1 more source

Forty-One Plant Extracts Screened for Dual Antidiabetic and Antioxidant Functions: Evaluating the Types of Correlation between α-Amylase Inhibition and Free Radical Scavenging

Molecules, 2021
Dysregulation of glucose homeostasis followed by chronic hyperglycemia is a hallmark of diabetes mellitus (DM), a disease spreading as a worldwide pandemic for which there is no satisfactory dietary treatment or cure.
Amir Bashkin, Manar Ghanim, Basheer Abu-Farich, Mahmoud Rayan, Reem Miari, Samer Srouji, Anwar Rayan, Mizied Falah   +7 more
doaj   +1 more source

The PPARγ2 P12A polymorphism is not associated with all-cause mortality in patients with type 2 diabetes mellitus [PDF]

, 2016
The high mortality risk of patients with type 2 diabetes mellitus may well be explained by the several comorbidities and/or complications. Also the intrinsic genetic component predisposing to diabetes might have a role in shaping the risk of diabetes ...
Alberico, Federica, Bacci, Simonetta, Cignarelli, Mauro, Copetti, Massimiliano, De Cosmo, Salvatore, Fontana, Andrea, Lamacchia, Olga, Marucci, Antonella, Mercuri, Luana, Pacilli, Antonio, Palena, Antonio, Prudente, Sabrina, Trischitta, Vincenzo, Viti, Raffaella   +13 more
core   +1 more source

Flaxseed- and chia seed-derived protein hydrolysates exhibiting enhanced in vitro antidiabetic, anti-obesity, and antioxidant properties

Frontiers in Sustainable Food Systems, 2023
This study investigated in vitro antidiabetic, anti-obesity, and antioxidant activities of chia seed protein hydrolysates (CSPHs) and flaxseed protein hydrolysates (FSPHs) generated using three food-grade proteases at the hydrolysis at intervals of 120 ...
Priti Mudgil, Feyisola Fisayo Ajayi, Amani Alkaabi, Maitha Alsubousi, Brij Pal Singh, Sajid Maqsood   +5 more
doaj   +1 more source

C-peptide: a predictor of cardiovascular mortality in subjects with established atherosclerotic disease [PDF]

, 2017
Aim: Insulin resistance and type 2 diabetes are independent risk factors for cardiovascular diseases. Levels of C-peptide are increased in these patients and its role in the atherosclerosis progression was studied in vitro and in vivo over the past ...
Ballanti, Marta, Cardellini, Marina, Cardolini, Iris, Davato, Francesca, Farcomeni, Alessio, Federici, Massimo, Grappasonni, Giulia, Guglielmi, Valeria, Ippoliti, Arnaldo, Menghini, Rossella, Morelli, Monica, Pecchioli, Chiara, Porzio, Ottavia, Rizza, Stefano   +13 more
core   +1 more source

The antioxidant and antidiabetic activity of the Arabian balsam tree “Commiphora gileadensis” in hyperlipidaemic male rats

Journal of Taibah University for Science, 2020
The leaf and twig aqueous extracts of Arabian balsam tree (Commiphora gileadensis) were tested to protect against alloxan-induced hyperglycaemia in hypercholesterolemic male rats.
Haddad A. El Rabey, Abdulbasit I. Al-Sieni, Madeha N. Al-Seeni, Mohammed A. Alsieni, Adel I. Alalawy, Fahad M. Almutairi   +5 more
doaj   +1 more source