Results 51 to 60 of about 181,241 (287)

Exploring Patients’ Profiles Associated With the Resolution of Acute Calcium Pyrophosphate Arthritis Treated With Colchicine and Prednisone: Post Hoc Analysis of a Randomized Controlled Trial

Arthritis Care &Research, EarlyView.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source

Multi-Mechanistic In Vitro Evaluation of Antihyperglycemic, Antioxidant and Antiglycation Activities of Three Phenolic-Rich Indian Red Rice Genotypes and In Silico Evaluation of Their Phenolic Metabolites

Foods, 2021
The study evaluated the antidiabetic potential of three traditional Indian red rice genotypes/RR (Kattuyanam/KA, Chennangi/CH & Karungkuruvai/KU) using a combination of in vitro, metabolomics (Quadrupole-Time of Flight-Liquid chromatography-Mass ...
Ashrita C. Haldipur, Nagarajan Srividya
doaj   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Phytochemicals profiling, in vitro and in vivo antidiabetic activity, and in silico studies on Ajuga iva (L.) Schreb.: A comprehensive approach

Open Chemistry
Ajuga iva (L.) Schreb. is a well-known antidiabetic medicinal plant used for several traditional medicine aspects in different areas of the world, including Libya. This study includes phytochemical analysis, antidiabetic evaluation, and in silico studies
Abomughaid Mosleh M., El-Shibani Fatma A. A., Abdulkarim Abdulnaser Kh., Abouzied Amr S., Sulaiman Ghassan M., Abomughayedh Ali M., Abdulsayid Munira M. F., Albukhaty Salim, Elrmali Naema, Al-Saffar Ali Z., El-khawaga Hend A., Mohammed Hamdoon A.   +11 more
doaj   +1 more source

Phytochemical Composition, Bioactive Compounds, and Antidiabetic Potential of Four Medicinal Plants Native to the UAE: Capparis spinosa, Citrullus colocynthis, Morus alba, and Rhazya stricta

Biology
This review highlights the significant therapeutic properties of four indigenous plants in the United Arab Emirates. These include Capparis spinosa L. (family: Capparaceae), commonly known as caper and locally referred to as Kabir; Citrullus colocynthis (
Seham M. Al Raish, Razan S. Almasri, Alaa S. Bedir, Aya A. Elkahwagy   +3 more
doaj   +1 more source

Green synthesis of ZnONps using Horse gram seed aqueous extract and its in vitro evaluation on antioxidant, antidiabetic, anticancer and DNA binding potential

Materials Research Express, 2023
The goal of this study was to access the green production of zinc oxide nanoparticles (G-ZnO NPs) using aqueous extract of horse gram seeds (Macrotyloma Uniflorum).
S Sudha, A Mary Saral
doaj   +1 more source

Sugarcane Straw Polyphenols as Potential Food and Nutraceutical Ingredient

Foods, 2022
The sugarcane processing industry generates a large amount of straw, which has a negative environmental impact, and high costs are associated with their elimination, wasting their potential bioactive value attributed to their richness in polyphenols.
Ana L. S. Oliveira, Maria João Carvalho, Diana Luazi Oliveira, Eduardo Costa, Manuela Pintado, Ana Raquel Madureira   +5 more
doaj   +1 more source

Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes [PDF]

, 2016
Background The cardiovascular effect of liraglutide, a glucagon-like peptide 1 analogue, when added to standard care in patients with type 2 diabetes, remains unknown. Methods In this double-blind trial, we randomly assigned patients with type 2 diabetes
Bergenstal, RM, Brown-Frandsen, K, Buse, JB, Daniels, GH, Kristensen, P, LEADER Steering Committee on behalf of the LEADER Trial Investigators, Mann, JF, Marso, SP, Nauck, MA, Nissen, SE, Pocock, S, Poulter, NR, Ravn, LS, Steinberg, WM, Stockner, M, Zinman, B   +15 more
core   +1 more source

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

A New Properties of Bajakah Tampala Wood (Spatholobus littoralis Hassk) Ethanol Extract Against α-Amylase Inhibition as Candidate Antidiabetic and Its Fortification in Kapok Honey

Jurnal Teknologi dan Industri Pertanian Indonesia
Bajakah Tampala extracted with ethanol was indicated to contain phenolic and flavonoids. So far, the ethanol extract of Bajakah Tampala wood has only been analyzed for its antioxidant activity.
Rista Anggriani, Noor Harini, Afifa Husna, Sukardi Sukardi, Maureen Danysha NS   +4 more
doaj   +1 more source