Results 101 to 110 of about 75,534 (305)

Seizure outcome after switching antiepileptic drugs: A matched, prospective study. [PDF]

open access: yes, 2016
OBJECTIVE: Outcomes after changing antiepileptic drugs (AEDs) have largely been studied in single cohort series. We recently reported the first study to examine this question in a controlled manner.
Finamore, Jon Marc   +5 more
core   +2 more sources

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Movement Disorders Induced by Antiepileptic Drugs

open access: yesPediatric Neurology Briefs, 2007
The prevalence and risk factors for the development of movement disorders, mainly parkinsonism and postural tremor, were analyzed in 201 adults (>18 years, mean 40 years) treated with valproate and newer antiepileptic drugs (AED) at the Epilepsy Clinic ...
J Gordon Millichap
doaj   +1 more source

Newer drugs for focal epilepsy in adults [PDF]

open access: yes, 2012
A 28 year old woman sees her general practitioner after experiencing what sounds like a convulsion without any apparent provoking factor. Over the past month she has also had “blank spells” during which her husband noticed her to be unresponsive.
Brodie, M., Kwan, P.
core   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

open access: yesEpilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann   +2 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

open access: yes, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Status Epilepticus Induced by Antiepileptic Drugs

open access: yesPediatric Neurology Briefs, 2006
Adolescent and adult patients with idiopathic generalized epilepsy (IGE) who developed paradoxical video-EEG documented status epilepticus (SE) precipitated by inappropriate antiepileptic drugs (AEDs) were studied retrospectively at Hopital Pasteur, Nice;
J Gordon Millichap
doaj   +1 more source

The 4-Aminopyridine Model of Acute Seizures in vitro Elucidates Efficacy of New Antiepileptic Drugs [PDF]

open access: yes, 2019
Up to date, preclinical screening for new antiepileptic substances is performed by a combination of different in vivo models of acute seizures, for which large numbers of animals are necessary.
Dag, Ramazan   +4 more
core   +1 more source

A two‐sample Mendelian randomization study and mediation analysis exploring the link between cathepsins and epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective This study aims to investigate the causal relationship between cathepsins and epilepsy, using Mendelian randomization (MR) and mediation analysis. Methods Publicly accessible summary statistics on epilepsy were obtained from FinnGen and the International League Against Epilepsy Consortium.
Huaiyu Sun   +7 more
wiley   +1 more source

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