Results 31 to 40 of about 68,714 (277)
Fungal biofilm resistance [PDF]
, 2012 Fungal biofilm infections have become increasingly recognised as a significant clinical problem. One of the major reasons behind this is the impact that these have upon treatment, as antifungal therapy often fails and surgical intervention is required ...
Ramage, Gordon +7 more
core +1 more source
HIV & AIDS Review. International Journal of HIV-Related Problems, 2020 Oropharyngeal candidiasis (OPC) is considered the most common fungal infection in human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients. Antifungal drug, azole group, is the preferred treatment.
Satutya Wicaksono +4 more
doaj +1 more source
mBio, 2022 Candida auris exhibits resistance to multiple antifungal drug classes and sterilization agents, posing threats to the immunocompromised worldwide. Among the four major geographical clades, the East Asian clade 2 isolates of C.
Aswathy Narayanan +10 more
doaj +1 more source
Artemisinin Targets Transcription Factor PDR1 and Impairs Candida glabrata Mitochondrial Function
Antioxidants, 2022 A limited number of antifungal drugs, the side-effect of clinical drugs and the emergence of resistance create an urgent need for new antifungal treatment agents. High-throughput drug screening and in-depth drug action mechanism analyzation are needed to
Pan Zhu +3 more
doaj +1 more source
Antifungal drug resistance mechanisms
Expert Review of Anti-infective Therapy, 2009 Antifungal resistance is a prominent feature in the management of invasive mycoses, with important implications for morbidity and mortality. Microbiological resistance, the most common cause of refractory infection, is associated with a fungal pathogen for which an antifungal MIC is higher than average or within the range designated as the resistant ...
Peman, Javier +2 more
openaire +4 more sources
Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi [PDF]
, 2008 Background: In contrast to the increasing numbers of agents for the treatment of invasive fungal infections, discoveries of new antifungal agents with therapeutic value in dermatomycoses are reported only rarely.
Borelli, Claudia +10 more
core +1 more source
Exploring the Molecular Basis of Antifungal Synergies Using Genome-Wide Approaches
Frontiers in Microbiology, 2012 Drug resistance poses a significant challenge in antifungal therapy since resistance has been found for all known classes of antifungal drugs. The discovery of compounds that can act synergistically with antifungal drugs is an important strategy to ...
Ameeta eAgarwal +6 more
doaj +1 more source
Turkish Journal of Hematology, 2018 Invasive fungal infections caused by drug-resistant organisms are an emerging threat to heavily immunosuppressed patients with hematological malignancies.
Maria N. Gamaletsou +2 more
doaj +1 more source
Experimental Evolution of Multidrug Resistance in Neurospora crassa under Antifungal Azole Stress
Journal of Fungi, 2022 Multidrug resistance, defined as the resistance to multiple drugs in different categories, has been an increasing serious problem. Limited antifungal drugs and the rapid emergence of antifungal resistance prompt a thorough understanding of how the ...
Mi Zhou +7 more
doaj +1 more source
Hsp21potentiates antifungal drug tolerance in Candida albicans [PDF]
, 2013 Peer ...
Hube Bernhard +8 more
core +1 more source